Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
ESRD clinical trials
Every US clinical trial registered for ESRD — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
12 US clinical trials · 3 currently recruiting
The research picture
ESRD has 12 registered US clinical trials, 3 of them open to new participants right now — about 25% of the total.
- 3
- recruiting participants now
- 25%
- of trials open to enrollment
- 3
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Fresenius Medical Care North America
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
SAVE-FistulaS: the SelfWrap-Assisted ArterioVEnous Fistulas Study
VenoStent
NCT06001827
SAfety of Regional Citrate Anticoagulation (SARCA Study)
Fresenius Medical Care North America
NCT05339139
Adding Urea to the Final Dialysis Fluid
University of California, San Francis
NCT06366230
Trial to Evaluate the Sirolimus-Eluting Collagen Implant on AV Fistula Outcomes
Vascular Therapies
NCT02513303
StatStrip A Glucose/Creatinine Meter System Lay User Study Evaluation
Nova Biomedical
NCT05144971
Reducing Chronic Kidney Disease Burden in an Underserved Population
Baylor Research Institute
NCT03832166
Timing of Antihypertensive Medications on Key Outcomes in Hemodialysis
Stanford University
NCT03327909
Pharmacodynamic Study of AZD1722 in End-stage Renal Disease Patients on Hemodialysis
Ardelyx
NCT01764854
Phosphate Kinetic Modeling 2
Fresenius Medical Care North America
NCT01252771
Sodium-restricted Diets and Symptoms in End Stage Renal Disease: An RCT
University of Pennsylvania
NCT02778516
Comparison of Different Glucose Concentrations in Dialysate of Hemodialysis Patients
Renal Research Institute
NCT00618033
Live Kidney Donors With Positive Anti-HCV Antibody, But Negative HCV PCR
University of Florida
NCT02669966
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 1 |
| Phase 3 | 2 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the ESRD Trial Landscape
ClinicalTrials.gov lists 12 US studies indexed under ESRD, and 3 of those are currently open to recruitment — roughly 25% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for ESRD shows 3 late-stage studies (Phase 3 and Phase 4 combined) alongside 2 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for ESRD is led by Fresenius Medical Care North America with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 12 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for ESRD?
PlainTrial tracks 12 US clinical trials for ESRD, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for ESRD?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.