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NCT07382167 · ClinicalTrials.gov registry record · Phase 3

A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults

A Phase 3 study of Chronic Idiopathic Constipation (CIC), sponsored by Ardelyx.

Recruiting
Registry status
Phase 3
Development phase
692
Enrollment target
20
Study locations

NCT07382167 is a Phase 3 study of Chronic Idiopathic Constipation (CIC) that is actively recruiting participants, run by Ardelyx. The registered enrollment target is 692 participants. The trial reports 20 study locations across 6 states.

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The verdict

NCT07382167, a Phase 3 study of Chronic Idiopathic Constipation (CIC), is actively recruiting participants, sponsored by Ardelyx.

RECRUITING
Registry status
Phase 3
Development phase
692 participants
Enrollment target
20
Study locations

Study Summary

This is a 26-week, multi-center, randomized, double-blind, placebo-controlled study with a 4-week treatment-free Safety Follow-up period to assess the safety and efficacy of tenapanor (5 mg, 25mg, and 50 mg) in adult patients with Chronic Idiopathic Constipation (CIC) when administered twice daily for 26 consecutive weeks.

Interventions

  • DRUG Placebo
  • DRUG Tenapanor 5 mg BID
  • DRUG Tenapanor 25 mg BID
  • DRUG Tenapanor 50 mg BID

Study Locations (20)

Florida

  • Proactive Clinical Research - Fort Lauderdale
  • Valencia Medical and Research Center - Miami
  • IMIC, Inc - Miami
  • Suncoast Clinical Research, Inc. - New Port Richey - New Port Richey
  • Sensible Healthcare, LLC - Ocoee
  • Harmony Clinical Research - Orlando - Orange City
  • Suncoast Clinical Research, Inc. - Palm Harbor - Palm Harbor
  • Clinical Research Center of Florida - Pompano Beach

California

  • Hope Clinical Research - Canoga Park - Canoga Park
  • GW Research Inc. - Chula Vista
  • Erick H. Alayo Medical Corporation - Chula Vista
  • 310 Clinical Research - Inglewood
  • Om Research LLC - Lancaster
  • Clinical Trials Research - Lincoln
  • Paragon Rx Clinical, Inc. - Santa Ana - Santa Ana

Arizona

  • Arizona Liver Health - Chandler - Chandler
  • Elite Clinical Studies - Phoenix

Arkansas

  • Arkansas Gastroenterology - North Little Rock - North Little Rock

Colorado

  • Rocky Mountain Gastroenterology (RMG) - Littleton - Lakewood

Georgia

  • Agile Clinical Research Trials, LLC - Atlanta

Trial Details

FieldValue
Enrollment Target 692 participants
Start Date 2026-01-13
Est. Completion 2027-06-04
Phase Phase 3

Sponsor

Ardelyx

25 total trials

What the Registry Record Tells You About NCT07382167

The ClinicalTrials.gov registry entry for NCT07382167 describes a study currently listed as recruiting, categorized as Phase 3. The registered enrollment target is 692 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ardelyx, which has 25 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Chronic Idiopathic Constipation (CIC) appearing as the primary indexed condition, and to 4 interventions - of which Placebo is the first listed.

NCT07382167 reports 20 study locations spanning 6 distinct geographic areas - top geographies include Florida, California, Arizona.

Frequently Asked Questions

What is clinical trial NCT07382167 about?

NCT07382167 is a clinical study titled "A 26-Wk Study to Assess Safety & Efficacy of Tenapanor for T/t of Chronic Idiopathic Constipation in Adults". This is a 26-week, multi-center, randomized, double-blind, placebo-controlled study with a 4-week treatment-free Safety Follow-up period to assess the safety and efficacy of tenapanor (5 mg, 25mg, and 50 mg) in adult patients with Chronic Idiopathic Constipation (CIC) when administered twice daily f...

What is the current status of trial NCT07382167?

This trial is currently recruiting. It is a Phase 3 study. The enrollment target is 692 participants. The study started on 2026-01-13. Estimated completion is 2027-06-04.

What conditions does trial NCT07382167 study?

This clinical trial studies the following conditions: Chronic Idiopathic Constipation (CIC).

What interventions are being tested in trial NCT07382167?

The interventions under investigation include: Placebo (DRUG), Tenapanor 5 mg BID (DRUG), Tenapanor 25 mg BID (DRUG), Tenapanor 50 mg BID (DRUG).

Who is sponsoring clinical trial NCT07382167?

This trial is sponsored by Ardelyx, which has 25 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07382167 being conducted?

This trial has 20 study locations across Arizona, Arkansas, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Chronic Idiopathic Constipation (CIC)

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.