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Hyperkalemia clinical trials
3 of 9 indexed Hyperkalemia trials are currently recruiting.
9 US clinical trials · 3 currently recruiting
Hyperkalemia is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Relypsa, running 1 of these trials.
The research picture
Hyperkalemia has 9 registered US clinical trials, 3 of them open to new participants right now, about 33% of the total.
- 3
- recruiting participants now
- 33%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Relypsa
Active & Recent Trials
9 total, page 1 of 1
AK+ Guard™ Pilot Study in Chronic Kidney Disease: Outpatient Diagnostic Accuracy and Remote Monitoring
AccurKardia
NCT07210021
Patiromer for Treatment of Hyperkalaemia in Children Under 12 Years of Age
Vifor Pharma
NCT05766839
Adding Urea to the Final Dialysis Fluid
University of California, San Francisco
NCT06366230
Evaluation of Patiromer in Heart Failure Patients
Relypsa
NCT00868439
A Study Evaluating the Safety and Efficacy of RDX013 for the Treatment of Hyperkalemia
Ardelyx
NCT04780841
Safety & Efficacy of Zirconium Silicate in Chronic Kidney Disease or Moderate Kidney Dysfunction With Mild Hyperkalemia
ZS Pharma
NCT01493024
Patiromer Efficacy to Reduce Episodic Hyperkalemia in End Stage Renal Disease Patients
Duke University
NCT03781089
Relationship Between Potassium Level in Venous Blood Samples Drawn and Heel Sticks In Infants and Newborns
The University of Texas Health Science Center, Houston
NCT01349218
Pharmacokinetic Study of Tacrolimus and Mycophenolate Mofetil in Kidney Transplant Recipients With Hyperkalemia Receiving Patiromer
The Rogosin Institute
NCT03229265
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 4 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Hyperkalemia Trial Landscape
9 indexed Hyperkalemia studies · 3 recruiting (33%).
Phase mix: 2 late (III/IV) vs 5 early (I/II).
Top sponsor: Relypsa (1 trial), 8 others listed. 9 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Hyperkalemia?
PlainTrial tracks 9 US clinical trials for Hyperkalemia, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Hyperkalemia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.