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Pharmacodynamic Study of AZD1722 in End-stage Renal Disease Patients on Hemodialysis
NCT01764854 · View on ClinicalTrials.gov ↗
Study Summary
The purpose of this study is to determine if the study drug is safe, tolerable and active in reducing fluid overload/weight gain between dialysis sessions for patients with End Stage Renal Disease on Hemodialysis.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG AZD1722 (in-patient)
- DRUG Placebo (in-patient)
- DRUG AZD1722 (out-patient)
Study Locations (3)
Arizona
- Southwest Clinical Research Institute — Tempe
Colorado
- Denver Nephrology — Denver
Minnesota
- DaVita Clinical Research — Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 88 participants |
| Start Date | 2013-01 |
| Est. Completion | 2013-10 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01764854
The ClinicalTrials.gov registry entry for NCT01764854 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 88 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ardelyx, which has 9 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 3 conditions, with End Stage Renal Disease appearing as the primary indexed condition, and to 4 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT01764854 reports 3 study locations spanning 3 distinct geographic areas — top geographies include Arizona, Colorado, Minnesota. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT01764854 about?
NCT01764854 is a clinical study titled "Pharmacodynamic Study of AZD1722 in End-stage Renal Disease Patients on Hemodialysis". The purpose of this study is to determine if the study drug is safe, tolerable and active in reducing fluid overload/weight gain between dialysis sessions for patients with End Stage Renal Disease on Hemodialysis.
What is the current status of trial NCT01764854?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 88 participants. The study started on 2013-01. Estimated completion is 2013-10.
What conditions does trial NCT01764854 study?
This clinical trial studies the following conditions: End Stage Renal Disease, ESRD, Chronic Kidney Disease Stage 5. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT01764854?
The interventions under investigation include: Placebo (DRUG), AZD1722 (in-patient) (DRUG), Placebo (in-patient) (DRUG), AZD1722 (out-patient) (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT01764854?
This trial is sponsored by Ardelyx, which has 9 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT01764854 being conducted?
This trial has 3 study locations across Arizona, Colorado, Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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