Alliance for Clinical Trials in Oncology
Alliance for Clinical Trials in Oncology sponsors 446 registered US clinical trials on ClinicalTrials.gov, 29 of them currently recruiting, and 346 completed. 142 of these trials are in Phase 3-4 (later-stage) and 235 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Breast Cancer, with 19 trials.
Trial Pipeline
446 total, page 9 of 9
Irinotecan in Treating Patients With Refractory Metastatic Breast Cancer
NCT00003351
Carboplatin, Paclitaxel, and Radiation Therapy in Treating Patients With Stage III Non-small Cell Lung Cancer That Cannot Be Removed During Surgery
NCT00003387
Genetic Study of Patients and Families With a History of Colorectal Cancer
NCT00003648
Quality of Life Assessment of Patients Receiving Treatment for Esophageal Cancer [Companion to CALGB-9781]
NCT00003381
Combination Chemotherapy With or Without Radiation Therapy in Treating Patients With Stage IIIA Non-small Cell Lung Cancer
NCT00003317
Hormone Therapy in Treating Patients With Prostate Cancer
NCT00003323
Cisplatin Plus Etoposide With or Without Paclitaxel in Treating Patients With Extensive-Stage Small Cell Lung Cancer
NCT00003299
Topotecan and Paclitaxel in Treating Patients With Recurrent or Refractory Small Cell Lung Cancer
NCT00003281
Fludarabine and Monoclonal Antibody Therapy in Treating Patients With Untreated B-cell Chronic Lymphocytic Leukemia
NCT00003248
Radiation Therapy and High-Dose Corticosteroids in Treating Older Patients With Primary CNS Non-Hodgkin's Lymphoma
NCT00003278
Irinotecan in Treating Patients With Advanced Gallbladder or Bile Duct Cancer
NCT00003276
Fludarabine Plus Octreotide in Treating Patients With Relapsed Low-Grade Non-Hodgkin's Lymphoma
NCT00002779
Radiation Therapy and Chemotherapy in Treating Patients With Cancer of the Pancreas or Stomach
NCT00003157
Glutamine in Preventing Acute Diarrhea in Patients With Pelvic Cancer
NCT00003170
Irinotecan in Treating Patients With Recurrent Glioma
NCT00003134
Irinotecan in Treating Patients With Advanced Cancer of the Stomach
NCT00003137
Paclitaxel in Treating Women With Recurrent Solid Tumors
NCT00003130
Paclitaxel With or Without Carboplatin in Treating Patients With Advanced Non-small Cell Lung Cancer
NCT00003117
Surgery With or Without Chemotherapy and Radiation Therapy in Treating Patients With Cancer of the Esophagus
NCT00003118
Genetic Markers in Patients With Colorectal Cancer
NCT00014079
Combination Chemotherapy in Treating Patients With Breast Cancer
NCT00003088
Paclitaxel in Treating Older Patients With Solid Tumors
NCT00003092
Gemcitabine and Cisplatin in Treating Patients With Metastatic Breast Cancer
NCT00002998
Interleukin-2 Plus Monoclonal Antibody Therapy in Treating Patients With Solid Tumors
NCT00002994
Surgery in Treating Patients With Prostate Cancer
NCT00002938
Detection of Early Metastases in Patients With Stage I Non-small Cell Lung Cancer
NCT00003006
Radiation Therapy With Androgen Suppression in Treating Patients With Prostate Cancer
NCT00002889
Study of Bone Marrow and Blood Samples in Patients With Untreated Acute Myeloid Leukemia or Acute Lymphoblastic Leukemia Enrolled on Clinical Trial CALGB-9621 or CALGB-9720
NCT01004965
Gene Mutations in Patients With Advanced Prostate Cancer That Is Not Responsive to Hormone Therapy
NCT00002924
Cladribine in Patients With Mantle Cell Lymphoma
NCT00002879
Etoposide in Treating Patients With Relapsed Non-Hodgkin's Lymphoma
NCT00002880
Antiandrogen Withdrawal in Treating Patients With Hormone-Refractory Prostate Cancer
NCT00002760
Chemotherapy Followed by Radiation Therapy in Treating Adults With Supratentorial Glioma
NCT00002806
Correlation of Menstrual Cycle Phase at Time of Primary Surgery With 5-Year Disease-Free Survival in Women With Stage I or Stage II Breast Cancer
NCT00002762
Chemotherapy Plus Peripheral Stem Cell Transplantation in Treating Patients With Acute Myeloid Leukemia in Second Remission
NCT00002768
Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer
NCT00002716
Study of Tissue and Blood Samples From Patients With Low-Grade Glioma
NCT01004523
Study of Tissue and Blood Samples From Patients With High-Grade Glioma
NCT01004887
Omega-3 Fatty Acids in Treating Patients With Advanced Cancer Who Have Significant Weight Loss
NCT00003077
Chemotherapy and Whole-Brain Radiation Therapy in Treating Patients With Primary Central Nervous System Non- Hodgkin's Lymphoma
NCT00002676
Talc in Treating Patients With Malignant Pleural Effusion
NCT00002622
Video-Assisted Surgery Followed by Radiation Therapy in Treating Patients With Stage I Non-small Cell Lung Cancer and Poor Heart and Lung Function
NCT00002624
Laparoscopic-Assisted Surgery Compared With Open Surgery in Treating Patients With Colon Cancer
NCT00002575
Aspirin in Treating Patients With Colorectal Cancer That Has Been Surgically Removed
NCT00002527
Cyclophosphamide and Filgrastim in Treating Patients With Stage IV, Relapsed, or Refractory Low-Grade Follicular Non-Hodgkin's Lymphoma
NCT00002501
Combination Chemotherapy in Treating Patients With Non-Hodgkin's Lymphoma or Acute Lymphocytic Leukemia
NCT00002494
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 26 |
| Phase 2 | 209 |
| Phase 3 | 142 |
What the Pipeline for Alliance for Clinical Trials in Oncology Shows
According to the ClinicalTrials.gov registry, Alliance for Clinical Trials in Oncology is linked to 446 US clinical trials across every stage of research activity. Of those, 29 studies are currently recruiting, about 7% of the sponsor's indexed portfolio, and 346 are already marked complete, representing roughly 78% of the total.
The phase mix for Alliance for Clinical Trials in Oncology reports 142 late-stage studies (Phase 3 and Phase 4 combined) and 235 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Alliance for Clinical Trials in Oncology is Breast Cancer with 19 linked trials, and 9 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.