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NCT00002760 · ClinicalTrials.gov registry record · Phase 3

Antiandrogen Withdrawal in Treating Patients With Hormone-Refractory Prostate Cancer

A Phase 3 study, sponsored by Alliance for Clinical Trials in Oncology.

Completed
Registry status
Phase 3
Development phase
260
Enrollment target

NCT00002760: Completed Phase 3 study, sponsored by Alliance for Clinical Trials in Oncology.

NCT00002760 is a Phase 3 study that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 260 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (66% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT00002760, a Phase 3 study, has completed, sponsored by Alliance for Clinical Trials in Oncology.

COMPLETED
Registry status
Phase 3
Development phase
260 participants
Enrollment target

Study Summary

RATIONALE: Antiandrogen withdrawal may be an effective treatment for prostate cancer. PURPOSE: Randomized phase III trial to study the effectiveness of ketoconazole and hydrocortisone for antiandrogen withdrawal in treating men with prostate cancer that is refractory to hormone therapy.

Interventions

  • DRUG ketoconazole
  • DRUG therapeutic hydrocortisone
  • OTHER Withdrawal of antiandrogen therapy

Trial Details

FieldValue
Enrollment Target 260 participants
Start Date 1996-08
Est. Completion 2009-04
Phase Phase 3

What the finished NCT00002760 record still lists

NCT00002760 is an interventional study that assigns participants to a tested intervention. The registered 260 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (66% lower).

The record links to 0 conditions, and to 3 interventions - of which ketoconazole is the first listed.

NCT00002760 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT00002760 about?

NCT00002760 is a clinical study titled "Antiandrogen Withdrawal in Treating Patients With Hormone-Refractory Prostate Cancer". RATIONALE: Antiandrogen withdrawal may be an effective treatment for prostate cancer. PURPOSE: Randomized phase III trial to study the effectiveness of ketoconazole and hydrocortisone for antiandrogen withdrawal in treating men with prostate cancer that is refractory to hormone therapy.

What is the current status of trial NCT00002760?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 260 participants. The study started on 1996-08. Estimated completion is 2009-04.

What interventions are being tested in trial NCT00002760?

The interventions under investigation include: ketoconazole (DRUG), therapeutic hydrocortisone (DRUG), Withdrawal of antiandrogen therapy (OTHER).

Who is sponsoring clinical trial NCT00002760?

This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT00002760's enrollment target sits among peer trials

260 1230th of 2000 higher than 767 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT00002760, the US trial registry maintained by the National Library of Medicine. NCT00002760 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.