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NCT00002716 · ClinicalTrials.gov registry record · Phase 3
Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer
A Phase 3 study of Colorectal Cancer and Metastatic Cancer, sponsored by Alliance for Clinical Trials in Oncology.
- Completed
- Registry status
- Phase 3
- Development phase
- 135
- Enrollment target
- 14
- Study locations
NCT00002716: Completed Phase 3 study of Colorectal Cancer and Metastatic Cancer, sponsored by Alliance for Clinical Trials in Oncology.
NCT00002716 is a Phase 3 study of Colorectal Cancer and Metastatic Cancer that has completed, run by Alliance for Clinical Trials in Oncology. The registered enrollment target is 135 participants, below the 1,544-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (91% lower). The trial reports 14 study locations across 8 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00002716, a Phase 3 study of Colorectal Cancer and Metastatic Cancer, has completed, sponsored by Alliance for Clinical Trials in Oncology.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 135 participants
- Enrollment target
- 14
- Study locations
Study Summary
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which chemotherapy regimen is more effective for metastatic colorectal cancer. PURPOSE: Randomized phase III trial to compare the effectiveness of intrahepatic floxuridine, leucovorin, and dexamethasone with that of systemic fluorouracil and leucovorin in treating patients who have unresectable liver metastases from colorectal cancer.
Conditions Studied
Interventions
- DRUG dexamethasone
- DRUG fluorouracil
- DRUG leucovorin calcium
- DRUG floxuridine
- PROCEDURE laparotomy
Study Locations (14)
Iowa
- CCOP - Cedar Rapids Oncology Project - Cedar Rapids
- CCOP - Iowa Oncology Research Association - Des Moines
- John Stoddard Cancer Center at Iowa Methodist Medical Center - Des Moines
- Mercy Cancer Center at Mercy Medical Center-Des Moines - Des Moines
- Iowa Lutheran Hospital - Des Moines
Pennsylvania
- Penn State Cancer Institute at Milton S. Hershey Medical Center - Hershey
- Fox Chase Cancer Center - Philadelphia
Other
- Instituto de Enfermedades Neoplasicas - Lima
- San Juan City Hospital - San Juan
Nebraska
- Midlands Cancer Center at Midlands Community Hospital - Papillion
New Mexico
- MBCCOP - University of New Mexico HSC - Albuquerque
Ohio
- MetroHealth Medical Center - Cleveland
Wisconsin
- CCOP - St. Vincent Hospital Cancer Center, Green Bay - Green Bay
New South Wales
- Westmead Hospital - Westmead
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 135 participants |
| Start Date | 1996-01 |
| Est. Completion | 2006-08 |
| Phase | Phase 3 |
What the finished NCT00002716 record still lists
NCT00002716 is an interventional study that assigns participants to a tested intervention. The registered 135 participants enrollment target is mid-sized for trials with a published cap, below the 1,544-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (91% lower).
The record links to 2 conditions, with Colorectal Cancer appearing as the primary indexed condition, and to 5 interventions - of which dexamethasone is the first listed.
NCT00002716 lists 14 locations in 8 states (Iowa, Pennsylvania, Other).
Frequently Asked Questions
What is clinical trial NCT00002716 about?
NCT00002716 is a clinical study titled "Combination Chemotherapy in Treating Patients With Liver Metastases From Colorectal Cancer". RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells. It is not yet known which chemotherapy regimen is more effective for metastatic colorectal cancer. PURPOSE: Randomized pha...
What is the current status of trial NCT00002716?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 135 participants. The study started on 1996-01. Estimated completion is 2006-08.
What conditions does trial NCT00002716 study?
This clinical trial studies the following conditions: Colorectal Cancer, Metastatic Cancer.
What interventions are being tested in trial NCT00002716?
The interventions under investigation include: dexamethasone (DRUG), fluorouracil (DRUG), leucovorin calcium (DRUG), floxuridine (DRUG), laparotomy (PROCEDURE).
Who is sponsoring clinical trial NCT00002716?
This trial is sponsored by Alliance for Clinical Trials in Oncology, which has 446 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00002716 being conducted?
This trial has 14 study locations across Iowa, Nebraska, New Mexico, Ohio, Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colorectal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00002716's enrollment target sits among peer trials
135 185th of 381 higher than 194 of 381 other Colorectal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colorectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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