Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Primary Open Angle Glaucoma or Ocular Hypertension: early-phase trial registry
2 of 4 indexed Primary Open Angle Glaucoma or Ocular Hypertension trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #4,115 of 28,707 conditions by registered trial count.
4 US clinical trials · 2 currently recruiting · #4,115 of 28,707 conditions by registered trial count
Primary Open Angle Glaucoma or Ocular Hypertension: 4 US clinical trials tracked, 2 recruiting.
Primary Open Angle Glaucoma or Ocular Hypertension is the subject of 4 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Aerie Pharmaceuticals, running 2 of these trials.
Enrollment posture brief
Registry condition primary-open-angle-glaucoma-or-ocular-hypertension
OPEN 2 | RECR 50% | LATE 1 | EARLY 2 | RANK #4115 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Primary Open Angle Glaucoma or Ocular Hypertension lists 2 open slots (50% of 4 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Primary Open Angle Glaucoma or Ocular Hypertension on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Primary Open Angle Glaucoma or Ocular Hypertension is recruiting above its size-band peers.
2 of 4 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
4 total, page 1 of 1
Effect of Rhopressa on Intraocular Pressure (IOP) in Patients With Primary Open-Angle Glaucoma or Ocular Hypertension Post-SLT
East Coast Institute for Research
NCT06865144
A Prospective Study on the Efficacy of Direct Selective Laser Trabeculoplasty (DSLT) in Achieving >20% Intraocular Pressure (IOP) Reduction Without Medications at 6 Months in Naive, Untreated Glaucoma Patients
Brian Shafer
NCT07076303
Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension
Aerie Pharmaceuticals
NCT03310580
Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
Aerie Pharmaceuticals
NCT03233308
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 2 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Primary Open Angle Glaucoma or Ocular Hypertension records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Primary Open Angle Glaucoma or Ocular Hypertension trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Primary Open Angle Glaucoma or Ocular Hypertension page
4 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Primary Open Angle Glaucoma or Ocular Hypertension trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Aerie Pharmaceuticals sponsors the most Primary Open Angle Glaucoma or Ocular Hypertension trials on record, review their full trial history before evaluating a specific study. See Aerie Pharmaceuticals's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Primary Open Angle Glaucoma or Ocular Hypertension condition card totals 4 registered trials; most-linked intervention Netarsudil Ophthalmic Solution 0.02%; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.