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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Normal Volunteers: early-phase trial registry

2 of 5 indexed Normal Volunteers trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #3,391 of 28,707 conditions by registered trial count.

5 US clinical trials · 2 currently recruiting · #3,391 of 28,707 conditions by registered trial count

Normal Volunteers: 5 US clinical trials tracked, 2 recruiting.

Normal Volunteers is the subject of 5 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Aerie Pharmaceuticals, running 1 of these trials.

Enrollment posture brief

Registry condition normal-volunteers

OPEN 2 | RECR 40% | LATE 0 | EARLY 3 | RANK #3391 | SPON 1

Nearest open-share peer: Achondroplasia (40% recruiting · 10 trials)

Ablation80%ACL Reconstruction80%Abuse, Drug60%Acceptability60%Normal Volunteers (this)40%
Open-enrollment share among volume-matched conditions near Normal Volunteers

Normal Volunteers lists 2 open slots (40% of 5 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Normal Volunteers on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Normal Volunteers is recruiting below its size-band peers.

    2 of 5 indexed trials (40%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Normal Volunteers research.

    Aerie Pharmaceuticals accounts for 1 of 5 trials (20%). 5 distinct sponsors appear on at least one study for this condition label.

  3. Typical Normal Volunteers enrolment sits around 108 participants.

    Median target enrolment is 108 among the 5 trials that report a genuine target (sentinel values excluded). 2 of those (40%) plan for fewer than 100 participants.

  4. Normal Volunteers splits between interventional and observational designs.

    3 interventional and 2 observational studies make up this index (60% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13

Phase Distribution

PhaseTrial count
Phase 1 3

Named interventions

Most-linked intervention names on Normal Volunteers records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

AR-12286 Drug
1 trials
MNTX tablet (Formulation 2) Drug
1 trials
MNTX tablet (Formulation 1) Drug
1 trials
ATTO-1310 Placebo Drug
1 trials
ATTO-1310 Drug
1 trials

US sites by state

Facility locations filed on Normal Volunteers trials. A trial with sites in several states counts in each.

New York 2 trials
Maryland 2 trials
Texas 1 trials
Nevada 1 trials
Missouri 1 trials
Indiana 1 trials
Florida 1 trials
California 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Normal Volunteers page

5 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Normal Volunteers condition card totals 5 registered trials; most-linked intervention AR-12286; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.