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NCT04498169 · ClinicalTrials.gov registry record · Phase 2

A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy

A Phase 2 study of Corneal Edema, sponsored by Aerie Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
40
Enrollment target
12
Study locations

NCT04498169 is a Phase 2 study of Corneal Edema that has completed, run by Aerie Pharmaceuticals. The registered enrollment target is 40 participants, below the 74-participant average among 4 other Corneal Edema trials with a reported enrollment target (46% lower). The trial reports 12 study locations across 10 states.

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The verdict

NCT04498169, a Phase 2 study of Corneal Edema, has completed, sponsored by Aerie Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
40 participants
Enrollment target
12
Study locations

Study Summary

Two different dosing regimens (QD and BID) of netarsudil will be studied to evaluate their efficacy in reducing or resolving corneal edema in subjects with FCD.

Conditions Studied

Corneal Edema

Interventions

  • DRUG Netarsudil Ophthalmic

Study Locations (12)

California

  • Orange County Ophthalmology - Garden Grove
  • Harvard Eye Associates - Laguna Hills

Minnesota

  • Chu Vision Institute - Bloomington
  • Minnesota Eye Care - Minnetonka

Kentucky

  • Cincinnati Eye Institute - Edgewood

Massachusetts

  • Advance Eye Associates - South Dartmouth

Missouri

  • Ophthalmology Associates - St Louis

North Dakota

  • Vance Thompson Vision - West Fargo

Ohio

  • Comprehensive Eye Care - Westerville

South Dakota

  • Vance Thompson Vision - Sioux Falls

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2020-09-17
Est. Completion 2021-08-11
Phase Phase 2

Sponsor

Aerie Pharmaceuticals

32 total trials

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What the Registry Record Tells You About NCT04498169

The ClinicalTrials.gov registry entry for NCT04498169 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 74-participant average among 4 other Corneal Edema trials with a reported enrollment target (46% lower). The listed sponsor is Aerie Pharmaceuticals, which has 32 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Corneal Edema appearing as the primary indexed condition, and to 1 intervention - of which Netarsudil Ophthalmic is the first listed.

NCT04498169 reports 12 study locations spanning 10 distinct geographic areas - top geographies include California, Minnesota, Kentucky.

Frequently Asked Questions

What is clinical trial NCT04498169 about?

NCT04498169 is a clinical study titled "A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy". Two different dosing regimens (QD and BID) of netarsudil will be studied to evaluate their efficacy in reducing or resolving corneal edema in subjects with FCD.

What is the current status of trial NCT04498169?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2020-09-17. Estimated completion is 2021-08-11.

What conditions does trial NCT04498169 study?

This clinical trial studies the following conditions: Corneal Edema.

What interventions are being tested in trial NCT04498169?

The interventions under investigation include: Netarsudil Ophthalmic (DRUG).

Who is sponsoring clinical trial NCT04498169?

This trial is sponsored by Aerie Pharmaceuticals, which has 32 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04498169 being conducted?

This trial has 12 study locations across California, Kentucky, Massachusetts, Minnesota, Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.