Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

COMPLETED Phase 2

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

NCT03310580 · View on ClinicalTrials.gov ↗

Study Summary

To test the safety and effectiveness of AR-13324 0.02% and 0.04% ophthalmic solution relative to placebo in Japanese/Japanese-American subjects with open-angle glaucoma or ocular hypertension in US.

Interventions

  • DRUG AR-13324 Ophthalmic Solution 0.02%
  • DRUG AR-13324 Ophthalmic Solution 0.04%
  • DRUG AR-13324 Ophthalmic Solution Placebo

Study Locations (20)

California

  • Milton M. Hom, OD FAAO FACAAISc — Azusa
  • Havana Research Institute — Burbank
  • Global Research Management — Glendale
  • Southern California Eye Physicians & Surgeons — Los Alamitos
  • East West Eye Institute — Los Angeles
  • USC Roski Eye Institute University of Souther California — Los Angeles
  • Global Research Foundation — Los Angeles
  • The Eye Research Foundation — Newport Beach
  • Southern California Eye Physicians Surgeons — Pasadena
  • North Bay Eye Associates Inc. — Petaluma
  • Martel Eye — Rancho Cordova
  • University of California — San Diego
  • AdvanceMed Clinical Research — San Diego
  • Glaucoma Center of San Francisco — San Francisco
  • Samsum Clinic — Santa Barbara

Arizona

  • Arizona Eye Center — Chandler
  • Arizona Glaucoma Specialists — Phoenix

Colorado

  • MCB Clinical Research Centers LLC — Colorado Springs

Georgia

  • Clayton Eye Clinical Research, LLC — Morrow

Hawaii

  • Jenkins Eye Care — Honolulu

Trial Details

FieldValue
Enrollment Target 42 participants
Start Date 2017-11-15
Est. Completion 2018-10-25
Phase Phase 2

Sponsor

Aerie Pharmaceuticals

9 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03310580

The ClinicalTrials.gov registry entry for NCT03310580 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Aerie Pharmaceuticals, which has 9 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Primary Open Angle Glaucoma or Ocular Hypertension appearing as the primary indexed condition, and to 3 interventions — of which AR-13324 Ophthalmic Solution 0.02% is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03310580 reports 20 study locations spanning 5 distinct geographic areas — top geographies include California, Arizona, Colorado. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03310580 about?

NCT03310580 is a clinical study titled "Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension". To test the safety and effectiveness of AR-13324 0.02% and 0.04% ophthalmic solution relative to placebo in Japanese/Japanese-American subjects with open-angle glaucoma or ocular hypertension in US.

What is the current status of trial NCT03310580?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 2017-11-15. Estimated completion is 2018-10-25.

What conditions does trial NCT03310580 study?

This clinical trial studies the following conditions: Primary Open Angle Glaucoma or Ocular Hypertension. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03310580?

The interventions under investigation include: AR-13324 Ophthalmic Solution 0.02% (DRUG), AR-13324 Ophthalmic Solution 0.04% (DRUG), AR-13324 Ophthalmic Solution Placebo (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03310580?

This trial is sponsored by Aerie Pharmaceuticals, which has 9 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03310580 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Georgia, Hawaii. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial