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NCT03310580 · ClinicalTrials.gov registry record · Phase 2

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

A Phase 2 study of Primary Open Angle Glaucoma or Ocular Hypertension, sponsored by Aerie Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
42
Enrollment target
20
Study locations

NCT03310580 is a Phase 2 study of Primary Open Angle Glaucoma or Ocular Hypertension that has completed, run by Aerie Pharmaceuticals. The registered enrollment target is 42 participants, below the 50-participant average among 3 other Primary Open Angle Glaucoma or Ocular Hypertension trials with a reported enrollment target (16% lower). The trial reports 20 study locations across 5 states.

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The verdict

NCT03310580, a Phase 2 study of Primary Open Angle Glaucoma or Ocular Hypertension, has completed, sponsored by Aerie Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
42 participants
Enrollment target
20
Study locations

Study Summary

To test the safety and effectiveness of AR-13324 0.02% and 0.04% ophthalmic solution relative to placebo in Japanese/Japanese-American subjects with open-angle glaucoma or ocular hypertension in US.

Interventions

  • DRUG AR-13324 Ophthalmic Solution 0.02%
  • DRUG AR-13324 Ophthalmic Solution 0.04%
  • DRUG AR-13324 Ophthalmic Solution Placebo

Study Locations (20)

California

  • Milton M. Hom, OD FAAO FACAAISc - Azusa
  • Havana Research Institute - Burbank
  • Global Research Management - Glendale
  • Southern California Eye Physicians & Surgeons - Los Alamitos
  • East West Eye Institute - Los Angeles
  • USC Roski Eye Institute University of Souther California - Los Angeles
  • Global Research Foundation - Los Angeles
  • The Eye Research Foundation - Newport Beach
  • Southern California Eye Physicians Surgeons - Pasadena
  • North Bay Eye Associates Inc. - Petaluma
  • Martel Eye - Rancho Cordova
  • University of California - San Diego
  • AdvanceMed Clinical Research - San Diego
  • Glaucoma Center of San Francisco - San Francisco
  • Samsum Clinic - Santa Barbara

Arizona

  • Arizona Eye Center - Chandler
  • Arizona Glaucoma Specialists - Phoenix

Colorado

  • MCB Clinical Research Centers LLC - Colorado Springs

Georgia

  • Clayton Eye Clinical Research, LLC - Morrow

Hawaii

  • Jenkins Eye Care - Honolulu

Trial Details

FieldValue
Enrollment Target 42 participants
Start Date 2017-11-15
Est. Completion 2018-10-25
Phase Phase 2

Sponsor

Aerie Pharmaceuticals

32 total trials

What the Registry Record Tells You About NCT03310580

The ClinicalTrials.gov registry entry for NCT03310580 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 50-participant average among 3 other Primary Open Angle Glaucoma or Ocular Hypertension trials with a reported enrollment target (16% lower). The listed sponsor is Aerie Pharmaceuticals, which has 32 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Primary Open Angle Glaucoma or Ocular Hypertension appearing as the primary indexed condition, and to 3 interventions - of which AR-13324 Ophthalmic Solution 0.02% is the first listed.

NCT03310580 reports 20 study locations spanning 5 distinct geographic areas - top geographies include California, Arizona, Colorado.

Frequently Asked Questions

What is clinical trial NCT03310580 about?

NCT03310580 is a clinical study titled "Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension". To test the safety and effectiveness of AR-13324 0.02% and 0.04% ophthalmic solution relative to placebo in Japanese/Japanese-American subjects with open-angle glaucoma or ocular hypertension in US.

What is the current status of trial NCT03310580?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 42 participants. The study started on 2017-11-15. Estimated completion is 2018-10-25.

What conditions does trial NCT03310580 study?

This clinical trial studies the following conditions: Primary Open Angle Glaucoma or Ocular Hypertension.

What interventions are being tested in trial NCT03310580?

The interventions under investigation include: AR-13324 Ophthalmic Solution 0.02% (DRUG), AR-13324 Ophthalmic Solution 0.04% (DRUG), AR-13324 Ophthalmic Solution Placebo (DRUG).

Who is sponsoring clinical trial NCT03310580?

This trial is sponsored by Aerie Pharmaceuticals, which has 32 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03310580 being conducted?

This trial has 20 study locations across Arizona, California, Colorado, Georgia, Hawaii. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.