Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT01474135 · ClinicalTrials.gov registry record · Phase 2
AR-12286 Fixed Dose Combination to Lower Elevated Intraocular Pressure
A Phase 2 study, sponsored by Aerie Pharmaceuticals.
- Completed
- Registry status
- Phase 2
- Development phase
- 93
- Enrollment target
NCT01474135: Completed Phase 2 study, sponsored by Aerie Pharmaceuticals.
NCT01474135 is a Phase 2 study that has completed, run by Aerie Pharmaceuticals. The registered enrollment target is 93 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (30% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01474135, a Phase 2 study, has completed, sponsored by Aerie Pharmaceuticals.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 93 participants
- Enrollment target
Study Summary
This is a double-masked, randomized, controlled study assessing the safety and ocular hypotensive efficacy of two AR 12286/travoprost fixed-dose combination products compared to Travatan® Z in patients with elevated intraocular pressure
Primary Outcome
Intraocular pressure
Interventions
- DRUG 0.25% AR-12286 / 0.004% travoprost
- DRUG 0.5% AR-12286, 0.004% travoprost
- DRUG 0.004% Travoprost
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 93 participants |
| Start Date | 2011-12 |
| Est. Completion | 2012-04 |
| Phase | Phase 2 |
What the finished NCT01474135 record still lists
NCT01474135 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 93 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (30% lower).
The record links to 0 conditions, and to 3 interventions - of which 0.25% AR-12286 / 0.004% travoprost is the first listed.
NCT01474135 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT01474135 about?
NCT01474135 is a clinical study titled "AR-12286 Fixed Dose Combination to Lower Elevated Intraocular Pressure". This is a double-masked, randomized, controlled study assessing the safety and ocular hypotensive efficacy of two AR 12286/travoprost fixed-dose combination products compared to Travatan® Z in patients with elevated intraocular pressure
What is the current status of trial NCT01474135?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 93 participants. The study started on 2011-12. Estimated completion is 2012-04.
What interventions are being tested in trial NCT01474135?
The interventions under investigation include: 0.25% AR-12286 / 0.004% travoprost (DRUG), 0.5% AR-12286, 0.004% travoprost (DRUG), 0.004% Travoprost (DRUG).
Who is sponsoring clinical trial NCT01474135?
This trial is sponsored by Aerie Pharmaceuticals, which has 32 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT01474135's enrollment target sits among peer trials
93 766th of 2000 higher than 1,234 of 2,000 other Phase 2 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02203526 · 93 participants · Phase 1
Phase 1 Study of Ibrutinib and Immuno-Chemotherapy Using Temozolomide, Etoposide, Doxil, Dexamethasone, Ibrutinib,Rituximab (TEDDI-R) in Primary CNS Lymphoma
- NCT03089554 · 93 participants · Phase 2
Evaluating Genomic Testing in Human Cancer & Outcomes of Targeted Therapies
- NCT05000021 · 93 participants · NA
Reducing Diabetes Distress Using Cognitive Behavioral Therapy in Young Adults With Type 1 Diabetes
- NCT05489887 · 93 participants · Phase 2
Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma
Similar registry start date
- NCT05988463 · started 2027-01-01 · Phase 1
Dose-Escalation Study of Artesunate Patients With IPF
- NCT07219706 · started 2026-12-10 · NA
Dietary Fiber and Time Restricted Eating
- NCT02831335 · started 2026-12-01
Technical Development of Multi-Parametric Renocerebral MRI
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia