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NCT02207491 · ClinicalTrials.gov registry record · Phase 3

Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

A Phase 3 study, sponsored by Aerie Pharmaceuticals.

Completed
Registry status
Phase 3
Development phase
411
Enrollment target

NCT02207491: Completed Phase 3 study, sponsored by Aerie Pharmaceuticals.

NCT02207491 is a Phase 3 study that has completed, run by Aerie Pharmaceuticals. The registered enrollment target is 411 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (47% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02207491, a Phase 3 study, has completed, sponsored by Aerie Pharmaceuticals.

COMPLETED
Registry status
Phase 3
Development phase
411 participants
Enrollment target

Study Summary

To evaluate the ocular hypotensive efficacy and ocular and systemic safety of AR-13324 Ophthalmic Solution, 0.02% compared to the active comparator Timolol maleate Ophthalmic Solution, 0.5%

Primary Outcome

The primary efficacy outcome is mean IOP

Interventions

  • OTHER Placebo
  • DRUG AR-13324 Ophthalmic Solution 0.02%
  • DRUG Timolol maleate Ophthalmic Solution 0.5% BID

Trial Details

FieldValue
Enrollment Target 411 participants
Start Date 2014-07
Est. Completion 2015-03
Phase Phase 3
Aerie Pharmaceuticals

32 total trials

What the finished NCT02207491 record still lists

NCT02207491 is an interventional study that assigns participants to a tested intervention. The registered 411 participants enrollment target is mid-sized for trials with a published cap, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (47% lower).

The record links to 0 conditions, and to 3 interventions - of which Placebo is the first listed.

NCT02207491 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02207491 about?

NCT02207491 is a clinical study titled "Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension". To evaluate the ocular hypotensive efficacy and ocular and systemic safety of AR-13324 Ophthalmic Solution, 0.02% compared to the active comparator Timolol maleate Ophthalmic Solution, 0.5%

What is the current status of trial NCT02207491?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 411 participants. The study started on 2014-07. Estimated completion is 2015-03.

What interventions are being tested in trial NCT02207491?

The interventions under investigation include: Placebo (OTHER), AR-13324 Ophthalmic Solution 0.02% (DRUG), Timolol maleate Ophthalmic Solution 0.5% BID (DRUG).

Who is sponsoring clinical trial NCT02207491?

This trial is sponsored by Aerie Pharmaceuticals, which has 32 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02207491's enrollment target sits among peer trials

411 909th of 2000 higher than 1,092 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02207491, the US trial registry maintained by the National Library of Medicine. NCT02207491 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.