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NCT03233308 · ClinicalTrials.gov registry record · Phase 2

Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

A Phase 2 study of Primary Open Angle Glaucoma or Ocular Hypertension, sponsored by Aerie Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
20
Enrollment target
2
Study locations

NCT03233308: Completed Phase 2 study of Primary Open Angle Glaucoma or Ocular Hypertension, sponsored by Aerie Pharmaceuticals.

NCT03233308 is a Phase 2 study of Primary Open Angle Glaucoma or Ocular Hypertension that has completed, run by Aerie Pharmaceuticals. The registered enrollment target is 20 participants, below the 57-participant average among 3 other Primary Open Angle Glaucoma or Ocular Hypertension trials with a reported enrollment target (65% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT03233308, a Phase 2 study of Primary Open Angle Glaucoma or Ocular Hypertension, has completed, sponsored by Aerie Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
20 participants
Enrollment target
2
Study locations

Study Summary

To evaluate the effect on trabecular outflow facility of Netarsudil ophthalmic solution 0.02% compared to placebo

Primary Outcome

Mean diurnal change from baseline in trabecular (tonographic) outflow facility.

Interventions

  • OTHER Placebo Comparator
  • DRUG Netarsudil Ophthalmic Solution 0.02%

Study Locations (2)

Minnesota

  • Mayo Clinic - Rochester

North Carolina

  • Duke Eye Center - Durham

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2017-10-20
Est. Completion 2018-04-19
Phase Phase 2
Aerie Pharmaceuticals

32 total trials

What the finished NCT03233308 record still lists

NCT03233308 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 57-participant average among 3 other Primary Open Angle Glaucoma or Ocular Hypertension trials with a reported enrollment target (65% lower).

The record links to 1 condition, with Primary Open Angle Glaucoma or Ocular Hypertension appearing as the primary indexed condition, and to 2 interventions - of which Placebo Comparator is the first listed.

NCT03233308 reports a single indexed study location in Minnesota, North Carolina.

Frequently Asked Questions

What is clinical trial NCT03233308 about?

NCT03233308 is a clinical study titled "Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)". To evaluate the effect on trabecular outflow facility of Netarsudil ophthalmic solution 0.02% compared to placebo

What is the current status of trial NCT03233308?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2017-10-20. Estimated completion is 2018-04-19.

What conditions does trial NCT03233308 study?

This clinical trial studies the following conditions: Primary Open Angle Glaucoma or Ocular Hypertension.

What interventions are being tested in trial NCT03233308?

The interventions under investigation include: Placebo Comparator (OTHER), Netarsudil Ophthalmic Solution 0.02% (DRUG).

Who is sponsoring clinical trial NCT03233308?

This trial is sponsored by Aerie Pharmaceuticals, which has 32 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03233308 being conducted?

This trial has 2 study locations across Minnesota, North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Source: ClinicalTrials.gov NCT03233308, the US trial registry maintained by the National Library of Medicine. NCT03233308 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.