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NCT01060579 · ClinicalTrials.gov registry record · Phase 2

Study of AR-12286 Versus Latanoprost in Patients With Elevated Intraocular Pressure

A Phase 2 study, sponsored by Aerie Pharmaceuticals.

Completed
Registry status
Phase 2
Development phase
217
Enrollment target

NCT01060579: Completed Phase 2 study, sponsored by Aerie Pharmaceuticals.

NCT01060579 is a Phase 2 study that has completed, run by Aerie Pharmaceuticals. The registered enrollment target is 217 participants, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (63% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01060579, a Phase 2 study, has completed, sponsored by Aerie Pharmaceuticals.

COMPLETED
Registry status
Phase 2
Development phase
217 participants
Enrollment target

Study Summary

A 28 day study of the safety and efficacy of two concentrations of topical AR-12286 in treating ocular hypertension and open-angle glaucoma compared to latanoprost. Hypothesis: The ocular hypotensive efficacy of each dose of AR-12286 ophthalmic solution will not be different from that of an active control.

Interventions

  • DRUG Latanoprost ophthalmic solution
  • DRUG AR-12286 0.5% ophthalmic solution
  • DRUG AR-12286 0.25% Ophthalmic solution

Trial Details

FieldValue
Enrollment Target 217 participants
Start Date 2010-02
Est. Completion 2010-08
Phase Phase 2
Aerie Pharmaceuticals

32 total trials

What the finished NCT01060579 record still lists

NCT01060579 is an interventional study that assigns participants to a tested intervention. The registered 217 participants enrollment target is mid-sized for trials with a published cap, above the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (63% higher).

The record links to 0 conditions, and to 3 interventions - of which Latanoprost ophthalmic solution is the first listed.

NCT01060579 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT01060579 about?

NCT01060579 is a clinical study titled "Study of AR-12286 Versus Latanoprost in Patients With Elevated Intraocular Pressure". A 28 day study of the safety and efficacy of two concentrations of topical AR-12286 in treating ocular hypertension and open-angle glaucoma compared to latanoprost. Hypothesis: The ocular hypotensive efficacy of each dose of AR-12286 ophthalmic solution will not be different from that of an active c...

What is the current status of trial NCT01060579?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 217 participants. The study started on 2010-02. Estimated completion is 2010-08.

What interventions are being tested in trial NCT01060579?

The interventions under investigation include: Latanoprost ophthalmic solution (DRUG), AR-12286 0.5% ophthalmic solution (DRUG), AR-12286 0.25% Ophthalmic solution (DRUG).

Who is sponsoring clinical trial NCT01060579?

This trial is sponsored by Aerie Pharmaceuticals, which has 32 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT01060579's enrollment target sits among peer trials

217 286th of 2000 higher than 1,715 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01060579, the US trial registry maintained by the National Library of Medicine. NCT01060579 (mid enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.