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ClinicalTrials.gov 9 recruiting now early-phase tilt small index

Vaping: early-phase trial registry

9 of 19 indexed Vaping trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #902 of 28,707 conditions by registered trial count.

19 US clinical trials · 9 currently recruiting · #902 of 28,707 conditions by registered trial count

Vaping: 19 US clinical trials tracked, 9 recruiting.

Vaping is the subject of 19 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of California, San Francisco, running 3 of these trials.

Enrollment posture brief

Registry condition vaping

OPEN 9 | RECR 47% | LATE 0 | EARLY 2 | RANK #902 | SPON 3

Nearest open-share peer: Breast Cancer Stage I (47% recruiting · 19 trials)

Amyotrophic Lateral Sclerosi52.6%Vaping (this)47%Anesthesia, Local42.1%Alcohol Consumption36.8%Attention Deficit Hyperactiv26.3%
Open-enrollment share among volume-matched conditions near Vaping

Vaping lists 9 open slots (47% of 19 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Vaping on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Vaping recruits in line with its size-band peers.

    9 of 19 indexed trials (47.4%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Vaping research.

    University of California, San Francisco accounts for 3 of 19 trials (15.8%). 15 distinct sponsors appear on at least one study for this condition label.

  3. Typical Vaping enrolment sits around 300 participants.

    Median target enrolment is 300 among the 19 trials that report a genuine target (sentinel values excluded). 7 of those (36.8%) plan for fewer than 100 participants.

  4. Vaping research is mostly interventional.

    16 interventional and 3 observational studies make up this index (84.2% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 22

Open and recent trials

19 total, page 1 of 1

RECRUITING NA 3,500 participants

Perceived Effectiveness of Vaping Prevention Ads Among Adolescents and Young Adults

UNC Lineberger Comprehensive Cancer Center

NCT07116837

RECRUITING NA 500 participants

Implementing an Adolescent and Young Adult (AYA) mHealth Vaping Cessation Program Into Oncology Clinics

St. Jude Children's Research Hospital

NCT05967585

RECRUITING NA 400 participants

Behavioral Intervention for Youth to Promote Vaping Cessation

Massachusetts General Hospital

NCT06765291

RECRUITING Phase 2 326 participants

A Trial of Varenicline for E-cigarette Cessation

Yale University

NCT07040566

RECRUITING NA 100 participants

Non-invasive Vagus Nerve Stimulation (nVNS) and Cognition in Young Adult Vapers - A Pilot Study

Temple University

NCT06804109

RECRUITING 100 participants

Vape Use Among Younger & Older Smokers

Abramson Cancer Center at Penn Medicine

NCT07214168

RECRUITING 90 participants

Early Detection of Vaping-related Vascular Diseases

University of Miami

NCT05454267

RECRUITING Phase 2 48 participants

Understanding the Clinical Pharmacology of Marijuana-Tobacco Co-administration

University of California, San Francisco

NCT05999383

RECRUITING NA 12 participants

Secondhand Effects of Hookah (i.e., Waterpipe) Smoke and Aerosol

University of California, Los Angeles

NCT04661683

ACTIVE NOT RECRUITING NA 3,840 participants

Network Intervention to Prevent Vaping

University of Rochester

NCT04678245

ACTIVE NOT RECRUITING 300 participants

Perioperative Vaping Complications

Navy Medical Center San Diego

NCT05912023

COMPLETED NA 1,681 participants

Text Message Quit Vaping Intervention for Adolescents

Truth Initiative

NCT04919590

COMPLETED NA 1,565 participants

Impact of Vaping Prevention Advertisements

UNC Lineberger Comprehensive Cancer Center

NCT04836455

COMPLETED NA 569 participants

PACE Vape Messaging Study

University of Vermont

NCT04450537

COMPLETED NA 500 participants

Social Media Intervention to Stop Nicotine and Cannabis Vaping Among Adolescents

University of California, San Francisco

NCT04707911

COMPLETED NA 71 participants

Vaper to Vaper: A Multimodal Mobile Peer Driven Intervention to Support Adolescents in Quitting Vaping

University of Massachusetts, Worcester

NCT05140915

COMPLETED NA 37 participants

Acute Effects of TCIG vs ECIG in PLWH

University of California, Los Angeles

NCT04568395

COMPLETED NA 36 participants

Nicotine Pharmacokinetics Following Use of the P4M3 Gen 2.0 E-Cigarette Compared to Smoking Cigarettes

Philip Morris Products S.A.

NCT05383508

COMPLETED NA 17 participants

Evaluating the Comparative Pharmacokinetics of Nicotine After Administration Via JUUL or Tobacco Cigarettes

University of California, San Francisco

NCT04053868

Phase Distribution

PhaseTrial count
Phase 2 2

Named interventions

Most-linked intervention names on Vaping records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Tobacco Other
1 trials
JUUL Other
1 trials
Cig Other
1 trials
CM35 Other
1 trials
CA35 Other
1 trials
Social Media Intervention Behavioral
1 trials
sham control Other
1 trials
ECIG Other
1 trials

US sites by state

Facility locations filed on Vaping trials. A trial with sites in several states counts in each.

California 6 trials
North Carolina 3 trials
Pennsylvania 2 trials
Massachusetts 2 trials
Vermont 1 trials
Tennessee 1 trials
South Carolina 1 trials
New York 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Vaping page

19 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Vaping condition card totals 19 registered trials; most-linked intervention Tobacco; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.