Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Traumatic Brain Injury: early-phase trial registry
75 of 172 indexed Traumatic Brain Injury trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #63 of 28,707 conditions by registered trial count.
172 US clinical trials · 75 currently recruiting · #63 of 28,707 conditions by registered trial count
Traumatic Brain Injury: 172 US clinical trials tracked, 75 recruiting.
Traumatic Brain Injury is the subject of 172 registered US clinical trials on ClinicalTrials.gov, 75 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 23 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 11 of these trials.
Enrollment posture brief
Registry condition traumatic-brain-injury
OPEN 75 | RECR 44% | LATE 5 | EARLY 23 | RANK #63 | SPON 11
Volume-matched condition peers
Nearest open-share peer: Binge-Eating Disorder (44% recruiting · 39 trials)
Traumatic Brain Injury lists 75 open slots (44% of 172 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Traumatic Brain Injury on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Traumatic Brain Injury is recruiting above its size-band peers.
75 of 172 indexed trials (43.6%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Traumatic Brain Injury trials is spread across many organizations.
VA Office of Research and Development accounts for 11 of 172 trials (6.4%). 95 distinct sponsors appear on at least one study for this condition label.
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Typical Traumatic Brain Injury enrolment sits around 80 participants.
Median target enrolment is 80 among the 172 trials that report a genuine target (sentinel values excluded). 99 of those (57.6%) plan for fewer than 100 participants.
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Traumatic Brain Injury research is mostly interventional.
122 interventional and 50 observational studies make up this index (70.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
172 total, page 4 of 4
Safety Study of RP-1127 (Glyburide for Injection) in Healthy Volunteers
Biogen
NCT01132703
rTMS to Improve Cognitive Function in TBI
VA Office of Research and Development
NCT02152540
Blended Reality Immersion for Geriatric Head Trauma: The BRIGHT Study
University of Maryland, Baltimore
NCT06074328
Eye Movement Recordings in the Diagnosis of Traumatic Brain Injury
VA Office of Research and Development
NCT00875589
Pilot Study of NeuroTriage Device in Patients with Potential Brain Injury And/or Impairment
University of Texas Southwestern Medical Center
NCT03761641
The Environment's Impact on Thinking When Added to Leg Cycling in People With TBI: VITAL
Kessler Foundation
NCT04901286
Optimizing Cognitive, Environmental, and Neuromotor Stimulation in Traumatic Brain Injury
Johns Hopkins University
NCT04073225
Optimizing Drug Doses in Critically Ill
University of North Carolina, Chapel Hill
NCT02437838
Clinical Trial to Improve the Magnetic Levator Prosthesis
Massachusetts Eye and Ear Infirmary
NCT03818204
Imaging Dopamine Function and Its Impact on Outcome After Traumatic Brain Injury (TBI)
Baylor Research Institute
NCT01850290
Effects of TT301 on Cytokine Levels Post Endotoxin Challenge
OPKO Health
NCT01357421
Myoelectric Upper Limb Orthosis Use by Persons With TBI and Stroke
Northwestern University
NCT03215771
A Pilot Randomized Controlled Trial: CoINTEGRATE
University of Michigan
NCT05732285
Sleep Quality, Heart Rate Variability and Anxiety Following Brain Injury
Shirley Ryan AbilityLab
NCT04652895
Vagus Nerve Stimulation to Treat Moderate Traumatic Brain Injury
CentraCare
NCT02974959
Telemedicine Brain Injury Coping Skills (BICS-T) Support Group for Brain Injury Survivors and Their Caregivers
Rehabilitation Hospital of Indiana
NCT04371211
Assessing Eye Tracking Features Following Sports-Related Concussion
Mayo Clinic
NCT02103803
Team Based Initiative Support
US Department of Veterans Affairs
NCT00771277
Restoration of Life Role Participation Through Cognitive and Motor Training for TBI
Malcom Randall VA Medical Center
NCT01158781
Treating Civilian Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation (ciTBI-HDtDCS)
The University of Texas at Dallas
NCT05408975
Traumatic Brain Injury Peripheral Nerve Study
Abbott Medical Devices
NCT01588691
Using the Xbox Kinect for Chronic TBI
Washington D.C. Veterans Affairs Medical Center
NCT02889289
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 11 |
| Phase 2 | 12 |
| Phase 3 | 3 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Traumatic Brain Injury records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Traumatic Brain Injury trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Traumatic Brain Injury page
172 registered trials, 75 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 75 Traumatic Brain Injury trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Traumatic Brain Injury trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Traumatic Brain Injury condition card totals 172 registered trials; most-linked intervention Placebo; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.