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NCT04073225 · ClinicalTrials.gov registry record · NA
Optimizing Cognitive, Environmental, and Neuromotor Stimulation in Traumatic Brain Injury
A NA study of Traumatic Brain Injury and Dementia Alzheimers, sponsored by Johns Hopkins University.
- Completed
- Registry status
- NA
- Development phase
- 23
- Enrollment target
- 1
- Study location
NCT04073225: Completed NA study of Traumatic Brain Injury and Dementia Alzheimers, sponsored by Johns Hopkins University.
NCT04073225 is a NA study of Traumatic Brain Injury and Dementia Alzheimers that has completed, run by Johns Hopkins University. The registered enrollment target is 23 participants, below the 277-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04073225, a NA study of Traumatic Brain Injury and Dementia Alzheimers, has completed, sponsored by Johns Hopkins University.
- COMPLETED
- Registry status
- NA
- Development phase
- 23 participants
- Enrollment target
- 1
- Study location
Study Summary
Patients with a history of traumatic brain injury (TBI) are at elevated risk for Alzheimer's disease and related dementias (ADRD). Improvements in TBI treatment may mitigate this risk. Complex motor activities, which combine physical and cognitive demands, have been shown to have well established neurocognitive benefits. This study seeks to address the need for novel TBI interventions optimized for adults with history of TBI by determining the effectiveness of an immersive computer game designed to integrating complex cognitive-motor interventions.
Primary Outcome
The Trail Making Test is a neuropsychological test of visual attention and task switching. It consists of two timed parts (Part A and B) in which the subject is instructed to connect a set of 25 dots as quickly as possible while still maintaining accuracy. Our primary measure was the difference in time (seconds) taking to complete Part B subtracted by Part A, which is an indicator of task-switching.
Conditions Studied
Interventions
- DEVICE MindPod Dolphin
- BEHAVIORAL 10 Keys to Healthy Aging
Study Locations (1)
Maryland
- Johns Hopkins Bayview - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2020-01-25 |
| Est. Completion | 2024-09-03 |
| Phase | NA |
What the finished NCT04073225 record still lists
NCT04073225 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 277-participant average among 171 other Traumatic Brain Injury trials with a reported enrollment target (92% lower).
The record links to 3 conditions, with Traumatic Brain Injury appearing as the primary indexed condition, and to 2 interventions - of which MindPod Dolphin is the first listed.
NCT04073225 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT04073225 about?
NCT04073225 is a clinical study titled "Optimizing Cognitive, Environmental, and Neuromotor Stimulation in Traumatic Brain Injury". Patients with a history of traumatic brain injury (TBI) are at elevated risk for Alzheimer's disease and related dementias (ADRD). Improvements in TBI treatment may mitigate this risk. Complex motor activities, which combine physical and cognitive demands, have been shown to have well established ne...
What is the current status of trial NCT04073225?
This trial is currently completed. It is a NA study. The enrollment target is 23 participants. The study started on 2020-01-25. Estimated completion is 2024-09-03.
What conditions does trial NCT04073225 study?
This clinical trial studies the following conditions: Traumatic Brain Injury, Dementia Alzheimers, Military Activity.
What interventions are being tested in trial NCT04073225?
The interventions under investigation include: MindPod Dolphin (DEVICE), 10 Keys to Healthy Aging (BEHAVIORAL).
Who is sponsoring clinical trial NCT04073225?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04073225 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Traumatic Brain Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04073225's enrollment target sits among peer trials
23 148th of 171 higher than 24 of 171 other Traumatic Brain Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Traumatic Brain Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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Long-term Brain Stimulation of the Motor Ventral Thalamus (VOP/VIM) to Improve Motor Function
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