Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Tobacco Use Cessation
Open-data reference.
37 US clinical trials · 12 currently recruiting
Active & Recent Trials
CONNECT Cancer Survivors With Tobacco Treatment
Washington University School of Medicine
NCT07020273
Mi QUIT CARE (Mile Square QUIT Community-Access-Referral-Expansion)
University of Illinois at Chicago
NCT04827420
Reach Through Equitable Implementation in Utah
University of Utah
NCT06881069
Comparative Effectiveness of Mobile Health Smoking Cessation Approaches Among Underserved Patients in Primary Care
University of Florida
NCT05415761
Smoking Cessation Program in the Construction Sector
University of Miami
NCT06098144
Cannabis-Tobacco Co-Use Treatment Study
Medical University of South Carolina
NCT06883162
Extended Intervention for Tobacco Use (EXIT) for People Experiencing Homelessness
University of California, San Francis
NCT07148232
Development of a Smoking Cessation Video Series
Wayne State University
NCT06443294
Integrating CHWs Into Prenatal Care for Maternal Smoking Cessation
Loma Linda University
NCT06438549
Comprehensive Tobacco Cessation for Cancer Patients and Survivors
Virginia Commonwealth University
NCT05805722
Oral Cannabidiol for Tobacco Cessation
Johns Hopkins University
NCT05445804
Trauma-Informed Care for Smoking Cessation for Pregnancy
University of California, San Francis
NCT07129590
Ask Advise Connect (AAC) Harris Heath CPRIT
M.D. Anderson Cancer Center
NCT01788787
Cessation Clinical Trial
Truth Initiative
NCT06806098
A Pragmatic Trial of Chronic Disease Approaches to Ameliorate Tobacco Related Cardiovascular Disease Health Disparities
University of Minnesota
NCT05671380
Development of UP2UTobacco for High School Youth
University of Virginia
NCT05396911
Reward Sensitivity and Pharmacotherapy for Smoking Cessation
M.D. Anderson Cancer Center
NCT02162849
Feasibility of Delivering VergeRx at FQHCs
University of Virginia
NCT06161675
Tobacco Quitlines:Adjunct to Dental Office Tobacco Intervention
Oregon Research Institute
NCT00384254
Interventions to Help More Low-income Smokers Quit
Washington University School of Medicine
NCT04311983
Helping Poor Smokers Quit
Washington University School of Medicine
NCT03194958
Quit and Win Contests to Improve Smoking Cessation Among College Students
University of Minnesota
NCT01096108
Disseminating an Evidence-based Tobacco Control Intervention for School Teachers in India
Glorian Sorensen
NCT05346991
Telephone Counseling for Snuff Users
HealthPartners Institute
NCT00265681
A Smart Approach to Treating Tobacco Use Disorder in Persons Living With HIV
Yale University
NCT04490057
Quit and Fit: Teen Smoking Cessation
West Virginia University
NCT01242657
Tobacco Tactics Website for Operating Engineers
University of Michigan
NCT01124110
Tobacco Cessation Via Doctors of Chiropractic
Oregon Research Institute
NCT00386945
Effectiveness of Bupropion for Treating Nicotine Dependence in Young People
National Institute on Drug Abuse (NIDA)
NCT00129272
A Facebook Intervention for Young Sexual and Gender Minority Smokers
University of California, San Francis
NCT03259360
Improving Adherence to Smoking Cessation Medication Among PLWHA
NYU Langone Health
NCT01898195
Evaluating a Web-Based Cardiovascular Disease Risk Factor Reduction Program Among American Indians
Black Hills Center for American Indian Health
NCT00608387
Connecting Alaska Native People to Quit Smoking
Mayo Clinic
NCT03645941
Preloading With Nicotine Replacement Therapy in HIV-positive Smokers to Improve Self-Efficacy and Quit Attempts
Brown University
NCT04994444
Engagement With an Adaptive Mobile Health Smoking Cessation Intervention
Massachusetts General Hospital
NCT04020718
Feasibility of a Culturally-Specific Video Text Cessation Intervention With AA Quitline Callers
Case Comprehensive Cancer Center
NCT03927976
Pilot Trial of Using SmokeBeat to Monitor and Increase Smoking Abstinence in Pregnant Women
University of Pennsylvania
NCT03209557
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 3 | 2 |
| Phase 4 | 5 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Tobacco Use Cessation Trial Landscape
ClinicalTrials.gov lists 37 US studies indexed under Tobacco Use Cessation, and 12 of those are currently open to recruitment — roughly 32% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Tobacco Use Cessation shows 7 late-stage studies (Phase 3 and Phase 4 combined) alongside 4 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Tobacco Use Cessation is led by Washington University School of Medicine with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 37 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Tobacco Use Cessation?
PlainTrial tracks 37 US clinical trials for Tobacco Use Cessation, of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Tobacco Use Cessation?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.