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NCT01898195 · ClinicalTrials.gov registry record · NA
Improving Adherence to Smoking Cessation Medication Among PLWHA
A NA study of Tobacco Use Cessation, sponsored by NYU Langone Health.
- Completed
- Registry status
- NA
- Development phase
- 158
- Enrollment target
- 1
- Study location
NCT01898195: Completed NA study of Tobacco Use Cessation, sponsored by NYU Langone Health.
NCT01898195 is a NA study of Tobacco Use Cessation that has completed, run by NYU Langone Health. The registered enrollment target is 158 participants, below the 880-participant average among 36 other Tobacco Use Cessation trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01898195, a NA study of Tobacco Use Cessation, has completed, sponsored by NYU Langone Health.
- COMPLETED
- Registry status
- NA
- Development phase
- 158 participants
- Enrollment target
- 1
- Study location
Study Summary
Smoking rates among individuals living with HIV/AIDS range between 47% and 65%, a prevalence that is roughly three times the rate of the general population. This elevated prevalence is alarming given the increased likelihood of numerous adverse health outcomes experienced by HIV-positive smokers. Cigarette smoking is associated with greater levels of HIV-related symptom burden and appears to decrease the effectiveness of HAART as assessed by both viral load and CD4 counts (Vidrine 2009, Marshall 2009, Vidrine 2007, Miguez-Burbane 2005). PLWHA who smoke are also at increased risk of infections and noninfectious pulmonary complications and both AIDS-associated and non-AIDS-associated malignancies compared to nonsmokers. This study will refine and pilot test a theory-driven smoking cessation intervention that enhances existing behavioral approaches by testing the impact of text message reminders to take varenicline and the feasibility and additional impact of including adherence-focused behavioral cessation counseling. The investigators propose to randomize 190 participants, recruited from three HIV/AIDS clinic, to a three arm pilot study that compares: 1) Standard Care (SC), 2) SC + text message reminders, and 3) SC + text message reminders + cell phone-delivered adherence-focused behavioral therapy (ABT). Participants in all three arms will receive varenicline for 12 weeks. The primary outcomes are adherence to varenicline and biochemically validated smoking abstinence at 12 weeks and 3-month follow-up from the time of study enrollment.
Primary Outcome
number of participants who took at least 80% prescribed dose since last interview, based on pill count
Conditions Studied
Interventions
- DRUG Varenicline
- BEHAVIORAL Text Message
- BEHAVIORAL Adherence Behavioral Therapy
Study Locations (1)
New York
- Spencer Cox Center for Health - New York
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 158 participants |
| Start Date | 2013-03 |
| Est. Completion | 2014-12 |
| Phase | NA |
What the finished NCT01898195 record still lists
NCT01898195 is an interventional study that assigns participants to a tested intervention. The registered 158 participants enrollment target is mid-sized for trials with a published cap, below the 880-participant average among 36 other Tobacco Use Cessation trials with a reported enrollment target (82% lower).
The record links to 1 condition, with Tobacco Use Cessation appearing as the primary indexed condition, and to 3 interventions - of which Varenicline is the first listed.
NCT01898195 reports a single indexed study location in New York.
Frequently Asked Questions
What is clinical trial NCT01898195 about?
NCT01898195 is a clinical study titled "Improving Adherence to Smoking Cessation Medication Among PLWHA". Smoking rates among individuals living with HIV/AIDS range between 47% and 65%, a prevalence that is roughly three times the rate of the general population. This elevated prevalence is alarming given the increased likelihood of numerous adverse health outcomes experienced by HIV-positive smokers. Ci...
What is the current status of trial NCT01898195?
This trial is currently completed. It is a NA study. The enrollment target is 158 participants. The study started on 2013-03. Estimated completion is 2014-12.
What conditions does trial NCT01898195 study?
This clinical trial studies the following conditions: Tobacco Use Cessation.
What interventions are being tested in trial NCT01898195?
The interventions under investigation include: Varenicline (DRUG), Text Message (BEHAVIORAL), Adherence Behavioral Therapy (BEHAVIORAL).
Who is sponsoring clinical trial NCT01898195?
This trial is sponsored by NYU Langone Health, which has 1,164 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01898195 being conducted?
This trial has 1 study location across New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Tobacco Use Cessation
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01898195's enrollment target sits among peer trials
158 24th of 36 higher than 13 of 36 other Tobacco Use Cessation trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Tobacco Use Cessation trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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