Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Tetralogy of Fallot: early-phase trial registry
3 of 8 indexed Tetralogy of Fallot trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 3 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Tetralogy of Fallot: 8 US clinical trials tracked, 3 recruiting.
Tetralogy of Fallot is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is Edwards Lifesciences, running 2 of these trials.
Enrollment posture brief
Registry condition tetralogy-of-fallot
OPEN 3 | RECR 38% | LATE 0 | EARLY 2 | RANK #2176 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Acute-graft-versus-host Disease (38% recruiting · 8 trials)
Tetralogy of Fallot lists 3 open slots (38% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Tetralogy of Fallot on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Tetralogy of Fallot is recruiting below its size-band peers.
3 of 8 indexed trials (37.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Tetralogy of Fallot research.
Edwards Lifesciences accounts for 2 of 8 trials (25%). 7 distinct sponsors appear on at least one study for this condition label.
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Typical Tetralogy of Fallot enrolment sits around 109 participants.
Median target enrolment is 109 among the 8 trials that report a genuine target (sentinel values excluded). 4 of those (50%) plan for fewer than 100 participants.
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Tetralogy of Fallot splits between interventional and observational designs.
4 interventional and 4 observational studies make up this index (50% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Molecular and Cellular Characterization of Cardiac Tissue in Postnatal Development
Emory University
NCT00243776
Pathophysiologic Mechanism for Arrhythmias and Impaired Aerobic Capacity in Tetralogy of Fallot and Other Congenital Heart Diseases
Mayo Clinic
NCT05122962
Beta-blocker Administration for Cardiomyocyte Division
Weill Medical College of Cornell University
NCT04713657
ALTERRA Post-Approval Study
Edwards Lifesciences
NCT05378386
ALTERRA: SAPIEN 3 THV With the Alterra Adaptive Prestent
Edwards Lifesciences
NCT03130777
Evaluation of the GORE PV1 Device in Patients With Pulmonary Valve Dysfunction
W.L.Gore & Associates
NCT03441971
Assessment of Right Ventricular Volume in Tetralogy of Fallott (TOF) Patients
VentriPoint Diagnostics
NCT01419756
Contrast Enhanced 3D Echocardiographic Quantification of Right Ventricular Volumes in Repaired CHD
Nemours Children's Clinic
NCT05186415
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Tetralogy of Fallot records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Tetralogy of Fallot trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Tetralogy of Fallot page
8 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Tetralogy of Fallot trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Edwards Lifesciences sponsors the most Tetralogy of Fallot trials on record, review their full trial history before evaluating a specific study. See Edwards Lifesciences's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Tetralogy of Fallot condition card totals 8 registered trials; most-linked intervention VentriPoint Medical System; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.