Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Achalasia: later-stage trial registry
4 of 8 indexed Achalasia trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 4 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Achalasia: 8 US clinical trials tracked, 4 recruiting.
Achalasia is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Chinese University of Hong Kong, running 1 of these trials.
Enrollment posture brief
Registry condition achalasia
OPEN 4 | RECR 50% | LATE 2 | EARLY 0 | RANK #2176 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Achalasia lists 4 open slots (50% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Achalasia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Achalasia is recruiting above its size-band peers.
4 of 8 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Achalasia trials is spread across many organizations.
Chinese University of Hong Kong accounts for 1 of 8 trials (12.5%). 8 distinct sponsors appear on at least one study for this condition label.
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Most Achalasia trials plan to enrol fewer than 100 people.
Median target enrolment is 80 among the 8 trials that report a genuine target (sentinel values excluded). 6 of those (75%) plan for fewer than 100 participants.
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Achalasia research is mostly interventional.
6 interventional and 2 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Prospective Evaluation of the Clinical Utility of Peroral Endoscopic Myotomy for Gastrointestinal Motility Disorders
AdventHealth
NCT05905016
POEM-F for Achalasia International Study
Chinese University of Hong Kong
NCT06042127
Comprehensive Esophageal Diagnostics Study
Emory University
NCT04641702
VZV in the Enteric Nervous System: Pathogenesis and Consequences
Vanderbilt University Medical Center
NCT05550194
Per-Oral Endoscopic Myotomy
University of California, San Diego
NCT01402518
Short Vs Standard Length Myotomy in Achalasia
Northwestern University
NCT04798547
Peroral Endoscopic Myotomy (POEM) for the Treatment of Achalasia
Ohio State University
NCT02073578
Peroral Endoscopic Myotomy (POEM) for Esophageal Motility
University of Pennsylvania
NCT02314741
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Achalasia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Achalasia trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Achalasia page
8 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Achalasia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Chinese University of Hong Kong sponsors the most Achalasia trials on record, review their full trial history before evaluating a specific study. See Chinese University of Hong Kong's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Achalasia condition card totals 8 registered trials; most-linked intervention Per-oral enodscopic myotomy; top US site state Tennessee. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.