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NCT00243776 · ClinicalTrials.gov registry record
Molecular and Cellular Characterization of Cardiac Tissue in Postnatal Development
A clinical trial of Congenital Heart Disease and Tetralogy of Fallot, sponsored by Emory University.
- Recruiting
- Registry status
- 600
- Enrollment target
- 1
- Study location
NCT00243776 is a study of Congenital Heart Disease and Tetralogy of Fallot that is actively recruiting participants, run by Emory University. The registered enrollment target is 600 participants, above the 464-participant average among 63 other Congenital Heart Disease trials with a reported enrollment target (29% higher). The trial reports 1 study location across 1 state.
The verdict
NCT00243776, a study of Congenital Heart Disease and Tetralogy of Fallot, is actively recruiting participants, sponsored by Emory University.
- RECRUITING
- Registry status
- 600 participants
- Enrollment target
- 1
- Study location
Study Summary
The study team will use small pieces of human hearts which are removed as part of a required surgical procedure to study different objectives. One of the objective is how calcium ions pass through the membrane of heart cells in order to tell the heart cell how much force to contract with when the heart beats. Investigators will also study the proteins and RNA of these pieces to determine how the newborn heart cells control their force of contraction differently from adult heart cells. Investigators hypothesize that infant hearts have different regulation of calcium entry than adult hearts. The study team also wants to study combinations of 3D cardiac spheres with multiple environmental cues that can improve functional and metabolic maturation of Human pluripotent stem cell-derived cardiomyocytes (hPSC-CMs) and generate a more clinically relevant cell model.
Conditions Studied
Study Locations (1)
Georgia
- Emory University School of Medicine - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2005-04 |
| Est. Completion | 2025-12-31 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00243776
The ClinicalTrials.gov registry entry for NCT00243776 describes a study currently listed as recruiting, categorized as an unspecified phase. The registered enrollment target is 600 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 464-participant average among 63 other Congenital Heart Disease trials with a reported enrollment target (29% higher). The listed sponsor is Emory University, which has 1,208 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Congenital Heart Disease appearing as the primary indexed condition, and to 0 interventions.
NCT00243776 reports 1 study location spanning 1 distinct geographic area - top geographies include Georgia.
Frequently Asked Questions
What is clinical trial NCT00243776 about?
NCT00243776 is a clinical study titled "Molecular and Cellular Characterization of Cardiac Tissue in Postnatal Development". The study team will use small pieces of human hearts which are removed as part of a required surgical procedure to study different objectives. One of the objective is how calcium ions pass through the membrane of heart cells in order to tell the heart cell how much force to contract with when the he...
What is the current status of trial NCT00243776?
This trial is currently recruiting. The enrollment target is 600 participants. The study started on 2005-04. Estimated completion is 2025-12-31.
What conditions does trial NCT00243776 study?
This clinical trial studies the following conditions: Congenital Heart Disease, Tetralogy of Fallot.
Who is sponsoring clinical trial NCT00243776?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00243776 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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