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NCT05696691 · ClinicalTrials.gov registry record · Phase 2
Ketamine & Crisis Response Plan for Suicidal Ideation in the ED
A Phase 2 study of Suicide, sponsored by The University of Texas Health Science Center at San Antonio.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 24
- Enrollment target
- 1
- Study location
NCT05696691: Recruiting Phase 2 study of Suicide, sponsored by The University of Texas Health Science Center at San Antonio.
NCT05696691 is a Phase 2 study of Suicide that is actively recruiting participants, run by The University of Texas Health Science Center at San Antonio. The registered enrollment target is 24 participants, below the 6,990-participant average among 92 other Suicide trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05696691, a Phase 2 study of Suicide, is actively recruiting participants, sponsored by The University of Texas Health Science Center at San Antonio.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 24 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this randomized pilot trial is to assess the feasibility of administering a combination of 100mg intramuscular (IM) ketamine and Crisis Response Plan (a short psychosocial intervention) for patients with acute suicidality in the context of the Emergency Department setting. This study will assess a combination of a pharmacologic intervention and a psychosocial one. The pharmacologic intervention is a one-time dose of 100mg ketamine delivered intramuscularly (IM) while the patient is in the ED. The psychosocial intervention under study is a brief, patient-centered therapy which takes, on average, 30 minutes to administer. Both interventions will be administered only once. The main questions this study aims to answer are: * Determine if 100mg of IM ketamine and Crisis Response Plan in combination results in greater short-term reductions in suicidal ideation in adult patients who report acutely elevated suicide risk during an ED visit. * Examine potential weight-based dose response differences in the reductions in suicidal ideation to determine if future treatment protocols with IM ketamine may benefit from weight-based dosing.
Primary Outcome
Number of enrolled subjects completing treatment within study parameters, with safety and side-effect profiles at or lower than published rates.
Conditions Studied
Interventions
- DRUG Ketamine Hydrochloride
- BEHAVIORAL Crisis Response Plan
Study Locations (1)
Texas
- University Hospital - San Antonio
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2023-01-06 |
| Est. Completion | 2026-12-31 |
| Phase | Phase 2 |
What NCT05696691 shows while recruiting
NCT05696691 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 24 participants, a relatively small participant target, below the 6,990-participant average among 92 other Suicide trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Suicide appearing as the primary indexed condition, and to 2 interventions - of which Ketamine Hydrochloride is the first listed.
NCT05696691 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05696691 about?
NCT05696691 is a clinical study titled "Ketamine & Crisis Response Plan for Suicidal Ideation in the ED". The goal of this randomized pilot trial is to assess the feasibility of administering a combination of 100mg intramuscular (IM) ketamine and Crisis Response Plan (a short psychosocial intervention) for patients with acute suicidality in the context of the Emergency Department setting. This study wil...
What is the current status of trial NCT05696691?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2023-01-06. Estimated completion is 2026-12-31.
What conditions does trial NCT05696691 study?
This clinical trial studies the following conditions: Suicide.
What interventions are being tested in trial NCT05696691?
The interventions under investigation include: Ketamine Hydrochloride (DRUG), Crisis Response Plan (BEHAVIORAL).
Who is sponsoring clinical trial NCT05696691?
This trial is sponsored by The University of Texas Health Science Center at San Antonio, which has 378 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05696691 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Suicide
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05696691's enrollment target sits among peer trials
24 85th of 92 higher than 7 of 92 other Suicide trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Suicide trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Suicide Risk Interventions
RECRUITING · Phase 2
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Safe Treatment for Emergency Presentation for Suicidal Ideation and Behavior in Youth
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Developing an Intervention to Promote Lethal Means Safety in Suicidal Adolescents
COMPLETED · Phase 2
-
Evaluation of a School-Based Training Program for Suicide Prevention
COMPLETED · Phase 2
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