Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 218 recruiting now early-phase tilt #9 of 28,963 conditions

Stroke: early-phase trial registry

218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #9 of 28,963 conditions by registered trial count.

456 US clinical trials · 218 currently recruiting · #9 of 28,963 conditions by registered trial count

Stroke: 456 US clinical trials tracked, 218 recruiting.

Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.

Open enrollment, early-phase tilt

Stroke has 456 registered US clinical trials, 218 of them open to new participants right now, about 48% of the total.

218
recruiting participants now
48%
of trials open to enrollment
16
in Phase 3-4 (later-stage)
27
top sponsor: VA Office of Research and Development

Corpus placement: #9 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Stroke is recruiting above its size-band peers.

    218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Stroke trials is spread across many organizations.

    VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.

  3. Most Stroke trials plan to enrol fewer than 100 people.

    Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.

  4. Stroke research is mostly interventional.

    385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 135Phase 234Phase 37Phase 49

Open and recent trials

456 total, page 8 of 10

COMPLETED NA 40 participants

Long-term Cardiac Monitoring After Cryptogenic Stroke (CMACS)

University of California, San Francisco

NCT00932425

COMPLETED NA 40 participants

Evaluating Error Augmentation for Neurorehabilitation

Shirley Ryan AbilityLab

NCT01574495

COMPLETED Phase 1 38 participants

The Effect of Aerobic Exercise on Learning After Stroke

University of Kansas

NCT00228306

COMPLETED NA 38 participants

Multifocal Brain Magnetic Stimulation in Chronic Ischemic Stroke

David Chiu, MD

NCT02817087

COMPLETED NA 38 participants

Improving Quality of Life for Veterans With Stroke and Psychological Distress

VA Office of Research and Development

NCT03645759

COMPLETED NA 37 participants

Evaluation of Bioness Integrated Therapy System (BITS) Touch Screen Technology to Improve Field Awareness

Gaylord Hospital

NCT04930822

COMPLETED NA 37 participants

Effects of Rehabilitation Robots-Morning Walk in Individuals With Hemiparesis

The University of Texas Medical Branch, Galveston

NCT06374706

COMPLETED Phase 2 36 participants

Augmenting Language Therapy for Aphasia: Levodopa

Shirley Ryan AbilityLab

NCT01429077

COMPLETED Phase 1 34 participants

Safety Study of RP-1127 (Glyburide for Injection) in Healthy Volunteers

Biogen

NCT01132703

COMPLETED NA 34 participants

Long Term Split Belt Treadmill Training for Stroke Recovery

Hugo W. Moser Research Institute at Kennedy Krieger

NCT01646216

COMPLETED NA 34 participants

Behavioral Economics and Mobility After Stroke (BE Mobile)

University of Pennsylvania

NCT04607811

COMPLETED 34 participants

Non-Heme Iron Load Quantification in the Brain - MRI of Patients With Stroke

University of Michigan

NCT01829386

COMPLETED 34 participants

Assessment of the Stroke Rehabilitation Assessment of Movement as a Clinical Tool

State University of New York - Upstate Medical University

NCT00635661

COMPLETED Phase 4 33 participants

Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity

The University of Texas Health Science Center, Houston

NCT00178646

COMPLETED NA 32 participants

Intention Treatment for Anomia

VA Office of Research and Development

NCT04267198

COMPLETED NA 32 participants

iADAPT to Support Strategy Training After Stroke

University of Pittsburgh

NCT03253601

COMPLETED NA 31 participants

BCI-controlled NMES in Subacute Stroke

University Hospital, Geneva

NCT03379532

COMPLETED Phase 2 30 participants

Virtual Environment Rehabilitation for Chronic Stroke

University of South Carolina

NCT01414686

COMPLETED Phase 2 30 participants

Robotic Upper-Limb Neurorehabilitation in Chronic Stroke Patient

US Department of Veterans Affairs

NCT00037934

COMPLETED Phase 2 30 participants

Cerebril™ in Patients With Lobar Hemorrhage Related to Cerebral Amyloid Angiopathy

Bellus Health Inc. - a GSK company

NCT00056238

COMPLETED NA 30 participants

Effects of Oropharyngeal Strengthening on Dysphagia in Patients Post-stroke

University of Wisconsin, Madison

NCT02322411

COMPLETED NA 29 participants

Effectiveness of Mindfulness After a Stroke

University of Southern California

NCT05029193

COMPLETED NA 28 participants

Piloting GETCare: A Remote Goal-based Education and Skills Training Program for Caregivers Poststroke

University of Utah

NCT05403021

COMPLETED Early Phase 1 27 participants

Mechanisms of Neuromuscular Fatigue Post Stroke

Medical College of Wisconsin

NCT01688570

COMPLETED Phase 1 27 participants

Computerized Attention Training for Individuals With Acquired Brain Injury

Posit Science Corporation

NCT01641432

COMPLETED 27 participants

Functional and Physiological Responses to Lokomat Therapy (Pilot Study)

US Department of Veterans Affairs

NCT00883142

COMPLETED NA 26 participants

TheraBracelet Phase I

TheraBracelet

NCT03318341

COMPLETED NA 25 participants

Motor Control Physical Therapist Support Stroke

University of Cincinnati

NCT04856527

COMPLETED Phase 2 25 participants

NeuroCognition After Carotid Recanalization

Duke University

NCT04219774

COMPLETED NA 25 participants

Robotically Augmented Mental Practice

Georgia Institute of Technology

NCT04962698

COMPLETED Phase 1 25 participants

Dopaminergic Enhancement of Rehabilitation Therapy Early After Stroke

University of California, Los Angeles

NCT05369533

COMPLETED NA 24 participants

A Pilot Study Investigating the Feasibility of the Saebo Arm Training Program on an Inpatient Population

Kessler Foundation

NCT00489580

COMPLETED NA 24 participants

Ipsihand Device Use in Stroke Patients to Assess Functional Motor Outcomes

Neurolutions

NCT04338971

COMPLETED NA 24 participants

Increasing Stroke Treatment Through Interventional Change Tactics Study

University of Michigan

NCT00349479

COMPLETED NA 24 participants

Comparing Mirror Therapy Rehabilitation Device to Conventional Mirror Therapy

Yale University

NCT06842888

COMPLETED NA 24 participants

Robot-Aided Assessment and Rehabilitation of Upper Extremity Function After Stroke

University of Maryland, Baltimore

NCT05854485

COMPLETED NA 24 participants

Aerobic Exercise in Patients With Stroke

Columbia University

NCT05429255

COMPLETED NA 23 participants

Active Limb Orthosis for Home-Use Stroke Hemiparetic Gait Rehabilitation

University of South Florida

NCT03649217

COMPLETED NA 23 participants

REEV SENSE for Gait Analysis in Post-stroke Gait Impairment (SENS-AG)

REEV

NCT06234878

COMPLETED Phase 1 23 participants

Safety Study of External Counterpulsation as a Treatment for Acute Ischemic Stroke

University of California, San Diego

NCT00983749

COMPLETED NA 23 participants

Exercise and Brain Stimulation for Post-stroke Depression

Medical University of South Carolina

NCT03056287

COMPLETED NA 23 participants

Treatment of Chronic Stroke With IpsiHand

Washington University School of Medicine

NCT02552368

COMPLETED NA 22 participants

Powered Orthotic Exoskeleton Training in Stroke

VA Office of Research and Development

NCT04241848

COMPLETED NA 22 participants

Self-management EdUcation and SuPport to Promote PsychOsocial Health Among StRoke Survivors and Informal Caregivers in a VirTual Stroke Community (SUPPORT)

The University of Texas Health Science Center, Houston

NCT05487144

COMPLETED NA 22 participants

Virtual Occupational Therapy Application

Barron Associates

NCT02706912

COMPLETED NA 22 participants

Combined Neural and Behavioral Therapies to Enhance Stroke Recovery

VA Office of Research and Development

NCT00929656

COMPLETED Early Phase 1 21 participants

New Tool to Enhance Post-stroke Upper Extremity Disability

Arizona State University

NCT05277389

COMPLETED NA 21 participants

Non-invasive Measurement of Cerebral Dynamic Autoregulation

University of Pennsylvania

NCT02442856

COMPLETED NA 21 participants

Heart-Brain Retraining for Stroke Rehabilitation

The Cleveland Clinic

NCT02076776

COMPLETED NA 21 participants

Activating Behavior for Lasting Engagement After Stroke

University of Pittsburgh

NCT03305731

← Previous Page 8 of 10 Next →

Phase Distribution

PhaseTrial count
Phase 1 35
Phase 2 34
Phase 3 7
Phase 4 9

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Stroke right now

218 recruiting of 456 indexed (48% open).

Phase mix: 16 late (III/IV) vs 69 early (I/II) (early-phase heavy).

Top sponsor: VA Office of Research and Development (27 trials), 9 others listed. 50 shown below, recruiting first. #9 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Stroke?

PlainTrial tracks 456 US clinical trials for Stroke, of which 218 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Stroke?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.