Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stroke: early-phase trial registry
218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #9 of 28,707 conditions by registered trial count.
456 US clinical trials · 218 currently recruiting · #9 of 28,707 conditions by registered trial count
Stroke: 456 US clinical trials tracked, 218 recruiting.
Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.
Enrollment posture brief
Registry condition stroke
OPEN 218 | RECR 48% | LATE 16 | EARLY 69 | RANK #9 | SPON 27
Volume-matched condition peers
Nearest open-share peer: Breast Cancer Stage II (48% recruiting · 23 trials)
Stroke lists 218 open slots (48% of 456 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Stroke is recruiting above its size-band peers.
218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stroke trials is spread across many organizations.
VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.
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Most Stroke trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.
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Stroke research is mostly interventional.
385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
456 total, page 9 of 10
Methylphenidate for Ptsd and Stroke Veterans
VA Office of Research and Development
NCT04885257
Body Weight Supported Treadmill Training vs. Overground Walking Training in Persons With Chronic Stroke
Stephanie Miller
NCT01180738
Safety of Intravenous Thrombolytics in Stroke on Awakening
Johns Hopkins University
NCT01643902
NewGait: A Low-Cost Rehabilitation System to Improve Post-Stroke Gait (Biomechanical Adaptations)
University of Michigan
NCT06269367
Intranasal Insulin and Post-stroke Cognition: A Pilot Study
Wake Forest University Health Sciences
NCT02810392
Non-invasive Brain Stimulation and Occupational Therapy To Enhance Stroke Recovery
Beth Israel Deaconess Medical Center
NCT00792428
Adapting Acceptance and Commitment Therapy for Stroke Survivors With Aphasia
University of Pittsburgh
NCT04984239
Clinical Trial to Improve the Magnetic Levator Prosthesis
Massachusetts Eye and Ear Infirmary
NCT03818204
Smartphone and 3D Printing Based Home Rehabilitation System for Chronic Stroke
State University of New York at Buffalo
NCT04363944
Combining Armodafinil With Neuro-rehabilitation to Improve Neurological Recovery and Reduce Disability Post-Stroke
Burke Rehabilitation Hospital
NCT01896128
Dietary Nitrate Supplements and Ischemic Stroke Recovery
Wake Forest University Health Sciences
NCT02838901
Brain Machine Interface Control of an Robotic Exoskeleton in Training Upper Extremity Functions in Stroke
The University of Texas Health Science Center, Houston
NCT01948739
In Vivo Imaging of Therapeutic Electric Current Flow
University of Florida
NCT02453763
Foot Posture in People With Paralysis on One Side After Stroke
University of Kansas
NCT00308035
Myoelectric Upper Limb Orthosis Use by Persons With TBI and Stroke
Northwestern University
NCT03215771
Exercise Intensity and Video Games: Persons Post-stroke
Rutgers, The State University of New Jersey
NCT04538326
Veteran-Centered Outcomes Using Qualitative and Quantitative Methods
US Department of Veterans Affairs
NCT00333580
Effects of Biofeedback on Walking Speed Post-stroke
University of Nebraska
NCT05420857
t-RNS After Hand Recovery in Chronic Stroke
Amit Sethi
NCT05489146
Transcranial Direct Current Stimulation (tDCS) in Chronic Stroke Recovery
University of Texas Southwestern Medical Center
NCT01014897
Post-stroke Fatigue, Inflammation, tDCS
Medical University of South Carolina
NCT05330988
Walk Assist Device to Improve Community Ambulation
Shirley Ryan AbilityLab
NCT03222505
Extension of the MIME Robotic System for Stroke Rehabilitation
US Department of Veterans Affairs
NCT00995774
Noninvasive VNS to Facilitate Excitability in Motor Cortex
Medical University of South Carolina
NCT04130646
DDN in Stroke--COBRE
Medical University of South Carolina
NCT05196737
Robot-Assisted Therapy and Motor Learning: An Active Learning Program for Stroke
Spaulding Rehabilitation Hospital
NCT02747433
Behavioral Activation for Post-Stroke Sedentary Behavior Using Telehealth
University of Minnesota
NCT05029284
Biofeedback to Increase Propulsion During Walking After Stroke
VA Office of Research and Development
NCT02667392
Primed vs. Unprimed rTMS in Chronic Stroke
University of Minnesota
NCT01757821
Effect of FES Interventions on Gait Dynamics in Stroke Population
Kessler Foundation
NCT01952613
Assistive Hip Exoskeleton Study for Stroke
Georgia Institute of Technology
NCT03924765
Mechanisms of Arm Recovery in Stroke Patients With Hand Paralysis
George Mason University
NCT03067818
Exercise-primed Upper Extremity Motor Practice in Chronic Stroke
Medical University of South Carolina
NCT04259424
Effect of Robot Rehabilitation Exercise Training on Motor Control After Stroke
Columbia University
NCT02331407
Assessment of Cortical Stimulation Combined With Rehabilitation to Enhance Recovery in Broca's Aphasia.
Northstar Neuroscience
NCT00170703
Constraint-induced Movement Therapy to Improve Gait and Mobility of People With Chronic Stroke
University of Alabama at Birmingham
NCT03114046
Conivaptan for the Reduction of Cerebral Edema in Intracerebral Hemorrhage- A Safety and Tolerability Study
Jesse Corry
NCT03000283
An Engineering-Based Balance Assessment and Training Platform
VA Office of Research and Development
NCT03994770
Facial and Body Motion Technology and Stroke
The University of Texas Health Science Center, Houston
NCT04592627
A Comparison of Conventional Physical Therapy, Powered Exoskeleton, and Hybrid Physical Therapy With Exoskeleton
Loma Linda University
NCT04648878
Transcranial Direct Current Stimulation for Improving Gait Training in Stroke
University of Arkansas
NCT01807637
iStride(TM) Device Used for Stroke Rehabilitation
University of South Florida
NCT02185404
Safety & Tolerability of Hypertonic Saline Administration Via Intraosseous Access
Ohio State University
NCT03276494
Virtual Reality Device for Rehabilitation of Stroke Patients
University of Alabama at Birmingham
NCT04139980
Impact of Custom Assistive and Adaptive Technology in Rehabilitation
Madonna Rehabilitation Hospital
NCT03567239
Hyperbaric Oxygen and Manipulative Therapies to Regain Function Post Stroke
Abington Memorial Hospital
NCT03352232
Advanced Cardiac Imaging To Predict Embolic Stroke On Brain MRI: A Pilot Study
Tulane University
NCT04769310
Novel Brain Signal Feedback Paradigm to Enhance Motor Learning After Stroke
VA Office of Research and Development
NCT02856035
Neurostimulation Exosuit Augmented Training (NEAT) in the Clinic
Boston University Charles River Campus
NCT07218107
A Brain Centered Neuroengineering Approach for Motor Recovery After Stroke: Combined rTMS and BCI Training
University of Minnesota
NCT02132520
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 35 |
| Phase 2 | 34 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Named interventions
Most-linked intervention names on Stroke records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Stroke trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Stroke page
456 registered trials, 218 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 218 Stroke trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VA Office of Research and Development sponsors the most Stroke trials on record, review their full trial history before evaluating a specific study. See VA Office of Research and Development's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stroke condition card totals 456 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.