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NCT01641432 · ClinicalTrials.gov registry record · Phase 1

Computerized Attention Training for Individuals With Acquired Brain Injury

A Phase 1 study of Stroke and Acquired Brain Injury, sponsored by Posit Science Corporation.

Completed
Registry status
Phase 1
Development phase
27
Enrollment target
1
Study location

NCT01641432: Completed Phase 1 study of Stroke and Acquired Brain Injury, sponsored by Posit Science Corporation.

NCT01641432 is a Phase 1 study of Stroke and Acquired Brain Injury that has completed, run by Posit Science Corporation. The registered enrollment target is 27 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT01641432, a Phase 1 study of Stroke and Acquired Brain Injury, has completed, sponsored by Posit Science Corporation.

COMPLETED
Registry status
Phase 1
Development phase
27 participants
Enrollment target
1
Study location

Study Summary

Problems with attention are a common and debilitating consequence of brain injury. Studies show that poor attention is the number one predictor of poor cognitive functioning one year post-injury. This is due to the fact that attention is a necessary component of more complex cognitive functions such as learning \& memory, multi-tasking and problem solving. In many cases, individuals may exhibit problems with spatial attention known as 'hemi-spatial neglect syndrome' or simply 'neglect'. Many studies now show that the processing machinery of the brain is plastic and remodeled throughout life by learning and experience, enabling the strengthening of cognitive skills or abilities. The investigators own research has shown that brief, daily computerized cognitive training that is sufficiently challenging, goal-directed and adaptive enables intact brain structures to restore balance in attention and compensate for disruptions in cognitive functioning.

Primary Outcome

Percent change on standardized measures of attention and executive function (all participants) using the ASCAN, Attentional Blink, Attention Capture Task, Landmark task, Conjunction Search task, SART, Verbal Fluency, CVLT-II, D-KEFS Stroop, and LNS assessments.

Interventions

  • BEHAVIORAL Active Comparator
  • BEHAVIORAL Tonic and Phasic Attention Training

Study Locations (1)

California

  • Brain Plasticity Institute - San Francisco

Trial Details

FieldValue
Enrollment Target 27 participants
Start Date 2011-07
Phase Phase 1
Posit Science Corporation

30 total trials

What the finished NCT01641432 record still lists

NCT01641432 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 27 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).

The record links to 3 conditions, with Stroke appearing as the primary indexed condition, and to 2 interventions - of which Active Comparator is the first listed.

NCT01641432 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT01641432 about?

NCT01641432 is a clinical study titled "Computerized Attention Training for Individuals With Acquired Brain Injury". Problems with attention are a common and debilitating consequence of brain injury. Studies show that poor attention is the number one predictor of poor cognitive functioning one year post-injury. This is due to the fact that attention is a necessary component of more complex cognitive functions such...

What is the current status of trial NCT01641432?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 27 participants. The study started on 2011-07.

What conditions does trial NCT01641432 study?

This clinical trial studies the following conditions: Stroke, Acquired Brain Injury, Hemispatial Neglect.

What interventions are being tested in trial NCT01641432?

The interventions under investigation include: Active Comparator (BEHAVIORAL), Tonic and Phasic Attention Training (BEHAVIORAL).

Who is sponsoring clinical trial NCT01641432?

This trial is sponsored by Posit Science Corporation, which has 30 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01641432 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Stroke

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT01641432's enrollment target sits among peer trials

27 322nd of 454 higher than 131 of 454 other Stroke trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT01641432, the US trial registry maintained by the National Library of Medicine. NCT01641432 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.