Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT03649217 · ClinicalTrials.gov registry record · NA
Active Limb Orthosis for Home-Use Stroke Hemiparetic Gait Rehabilitation
A NA study of Stroke, sponsored by University of South Florida.
- Completed
- Registry status
- NA
- Development phase
- 23
- Enrollment target
- 4
- Study locations
NCT03649217: Completed NA study of Stroke, sponsored by University of South Florida.
NCT03649217 is a NA study of Stroke that has completed, run by University of South Florida. The registered enrollment target is 23 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 4 study locations across 4 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03649217, a NA study of Stroke, has completed, sponsored by University of South Florida.
- COMPLETED
- Registry status
- NA
- Development phase
- 23 participants
- Enrollment target
- 4
- Study locations
Study Summary
The objective of this research is to test a passive shoe to correct gait in individuals with asymmetric walking patterns. This will be done in a clinic and within their own home. Individuals with central nervous system damage, such as stroke, often have irregular walking patterns and have difficulty walking correctly. Recent research has shown that using a split-belt treadmill can create after-effects that temporarily correct the inefficient walking patterns. However, the corrected walking pattern does not efficiently transfer from the treadmill to walking over ground. The iStride, formerly known as the Gait Enhancing Mobile Shoe (GEMS), may allow a patient to practice walking in many different locations, such as their own home, which we hypothesize will result in a more permanent transfer of learned gait patterns. To enable long-term use, our proposed shoe design is passive and uses the wearer's natural forces exerted while walking to generate the necessary motions.
Primary Outcome
This test is to also help determine gait velocity/speed.
Conditions Studied
Interventions
- DEVICE wearing the iStride device
Study Locations (4)
Florida
- University of South Florida - Tampa
North Carolina
- homes throughout Charlotte, NC - Charlotte
Tennessee
- homes throughout Memphis, TN - Memphis
Vermont
- homes throughout Burlington, VT - Burlington
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 23 participants |
| Start Date | 2018-07-09 |
| Est. Completion | 2019-12-09 |
| Phase | NA |
What the finished NCT03649217 record still lists
NCT03649217 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 23 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which wearing the iStride device is the first listed.
NCT03649217 reports a single indexed study location in Florida, North Carolina, Tennessee.
Frequently Asked Questions
What is clinical trial NCT03649217 about?
NCT03649217 is a clinical study titled "Active Limb Orthosis for Home-Use Stroke Hemiparetic Gait Rehabilitation". The objective of this research is to test a passive shoe to correct gait in individuals with asymmetric walking patterns. This will be done in a clinic and within their own home. Individuals with central nervous system damage, such as stroke, often have irregular walking patterns and have difficulty...
What is the current status of trial NCT03649217?
This trial is currently completed. It is a NA study. The enrollment target is 23 participants. The study started on 2018-07-09. Estimated completion is 2019-12-09.
What conditions does trial NCT03649217 study?
This clinical trial studies the following conditions: Stroke.
What interventions are being tested in trial NCT03649217?
The interventions under investigation include: wearing the iStride device (DEVICE).
Who is sponsoring clinical trial NCT03649217?
This trial is sponsored by University of South Florida, which has 252 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03649217 being conducted?
This trial has 4 study locations across Florida, North Carolina, Tennessee, Vermont. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03649217's enrollment target sits among peer trials
23 347th of 454 higher than 104 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Tracking a Tactile Signal Along the Nervous System
RECRUITING · NA
-
Transcranial Direct Current Stimulation (tDCS) With Verb Network Strengthening Treatment (VNeST) in Chronic Aphasia
RECRUITING · NA
-
Strategy Training for Individuals With Unilateral Neglect
RECRUITING · NA
-
Weight Loss and ExeRcise
RECRUITING · NA
-
Safety and Feasibility of an ExoNET for Supination Assistance for Stroke Survivors
RECRUITING · NA
-
Deep Brain Stimulation Motor Ventral Thalamus (VOP/VIM) for Restoration of Speech and Upper-limb Function in People With Subcortical Stroke
RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03616041 · 23 participants
Capsule Endoscopy for Severe Hematochezia
- NCT04348747 · 23 participants · Phase 2
Dendritic Cell Vaccines Against Her2/Her3 and Pembrolizumab for the Treatment of Brain Metastasis From Triple Negative Breast Cancer or HER2+ Breast Cancer
- NCT04587687 · 23 participants · Phase 2
Brentuximab Vedotin and Bendamustine for the Treatment of Relapsed or Refractory Follicular Lymphoma
- NCT04715022 · 23 participants · Phase 1
Sympathetic-vascular Dysfunction in Obesity and Insulin Resistance (Vitamin C Study)
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI