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NCT00178646 · ClinicalTrials.gov registry record · Phase 4
Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity
A Phase 4 study of Stroke and Brain Injuries, sponsored by The University of Texas Health Science Center, Houston.
- Completed
- Registry status
- Phase 4
- Development phase
- 33
- Enrollment target
- 2
- Study locations
NCT00178646: Completed Phase 4 study of Stroke and Brain Injuries, sponsored by The University of Texas Health Science Center, Houston.
NCT00178646 is a Phase 4 study of Stroke and Brain Injuries that has completed, run by The University of Texas Health Science Center, Houston. The registered enrollment target is 33 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00178646, a Phase 4 study of Stroke and Brain Injuries, has completed, sponsored by The University of Texas Health Science Center, Houston.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 33 participants
- Enrollment target
- 2
- Study locations
Study Summary
The study seeks to compare the effectiveness of three preparations of BOTOX-A® in treating muscle tightness and spasms in the feet and ankles of people with stroke.
Primary Outcome
The Ashworth Scale measures resistance during passive soft-tissue stretching and is used as a simple measure of spasticity. Score on the Ashworth scores ranges from 0-4, with 4 being the worst: 0 - No increase in muscle tone 1. \- Slight increase in muscle tone, manifested by a catch and release or by minimal resistance at the end of the range of motion when the affected part(s) is moved in flexion or extension 2. \- More marked increase in muscle tone through most of the range of motion, but
Conditions Studied
Interventions
- DRUG Botox
Study Locations (2)
New Jersey
- Kessler Institute for Rehabiliation - West Orange
Texas
- Memorial Hermann Hospital - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2002-01 |
| Est. Completion | 2010-03 |
| Phase | Phase 4 |
What the finished NCT00178646 record still lists
NCT00178646 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (100% lower).
The record links to 3 conditions, with Stroke appearing as the primary indexed condition, and to 1 intervention - of which Botox is the first listed.
NCT00178646 reports a single indexed study location in New Jersey, Texas.
Frequently Asked Questions
What is clinical trial NCT00178646 about?
NCT00178646 is a clinical study titled "Comparative Efficacy of Three Preparations of Botox-A in Treating Spasticity". The study seeks to compare the effectiveness of three preparations of BOTOX-A® in treating muscle tightness and spasms in the feet and ankles of people with stroke.
What is the current status of trial NCT00178646?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 33 participants. The study started on 2002-01. Estimated completion is 2010-03.
What conditions does trial NCT00178646 study?
This clinical trial studies the following conditions: Stroke, Brain Injuries, Spasticity.
What interventions are being tested in trial NCT00178646?
The interventions under investigation include: Botox (DRUG).
Who is sponsoring clinical trial NCT00178646?
This trial is sponsored by The University of Texas Health Science Center, Houston, which has 732 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00178646 being conducted?
This trial has 2 study locations across New Jersey, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00178646's enrollment target sits among peer trials
33 292nd of 454 higher than 163 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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