Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Stroke: early-phase trial registry
218 of 456 indexed Stroke trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #9 of 28,963 conditions by registered trial count.
456 US clinical trials · 218 currently recruiting · #9 of 28,963 conditions by registered trial count
Stroke: 456 US clinical trials tracked, 218 recruiting.
Stroke is the subject of 456 registered US clinical trials on ClinicalTrials.gov, 218 of them currently open to new participants. 16 are in Phase 3-4 (later-stage) and 69 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 27 of these trials.
Open enrollment, early-phase tilt
Stroke has 456 registered US clinical trials, 218 of them open to new participants right now, about 48% of the total.
- 218
- recruiting participants now
- 48%
- of trials open to enrollment
- 16
- in Phase 3-4 (later-stage)
- 27
- top sponsor: VA Office of Research and Development
Corpus placement: #9 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.
Key findings
What ClinicalTrials.gov does not surface for Stroke on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.
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Stroke is recruiting above its size-band peers.
218 of 456 indexed trials (47.8%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Stroke trials is spread across many organizations.
VA Office of Research and Development accounts for 27 of 456 trials (5.9%). 181 distinct sponsors appear on at least one study for this condition label.
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Most Stroke trials plan to enrol fewer than 100 people.
Median target enrolment is 54 among the 455 trials that report a genuine target (sentinel values excluded). 309 of those (67.9%) plan for fewer than 100 participants.
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Stroke research is mostly interventional.
385 interventional and 71 observational studies make up this index (84.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
456 total, page 7 of 10
Hypovitaminosis D in Neurocritical Patients
University of Utah
NCT02881957
SEdation Versus General Anesthesia for Endovascular Therapy in Acute Ischemic Stroke
The University of Texas Health Science Center, Houston
NCT03263117
Stroke Self-Management: Effect on Function and Stroke Specific Quality of Life
VA Office of Research and Development
NCT01507688
Sleep Apnea in TIA/Stroke: Reducing Cardiovascular Risk With Positive Airway Pressure
Yale University
NCT01446913
Stroke Team Remote Evaluation Using a Digital Observation Camera
University of California, San Diego
NCT00283868
A Culturally-Based Palliative Care Tele-consult Program for Rural Southern Elders
University of Alabama at Birmingham
NCT03767517
Does Detailed Informed Consent for Cardiopulmonary Resuscitation and Mechanical Ventilation Impact Patients' Decisions and Outcomes?
Jewish Hospital, Cincinnati, Ohio
NCT01878968
Reducing Stroke Risk in African-American Men
Case Western Reserve University
NCT04402125
Brain Electrical Stimulation to Enhance Recovery After Stroke
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00085657
Intravenous Thrombolysis Plus Hypothermia for Acute Treatment of Ischemic Stroke
University of California, San Diego
NCT00283088
Mechanical Retrieval and Recanalization of Stroke Clots Using Embolectomy
University of California, Los Angeles
NCT00389467
Spinal COrd NeuromodulaTor by SpIneX and ScoNE to Treat NeurogeniC BladdEr - SCONE "CONTINENCE" Clinical Study
SpineX
NCT05301335
Efficacy of the WalkAide and AFOs for CVA
Innovative Neurotronics
NCT00216320
Personalized Patient and Caregiver Education After Stroke
University of Pennsylvania
NCT05118503
Comparison of Safety and Efficacy of Tizanidine Hydrochloride Capsules Versus Zanaflex® (Tizanidine Hydrochloride Tablets) Taken While in the Fed State (Just After a Meal) and in the Fasted State (Before a Meal) in Patients With Moderate to Severe Spasticity.
Elan Pharmaceuticals
NCT00047580
Movement-2-Music: Lakeshore Examination of Activity, Disability, and Exercise Response Study
University of Alabama at Birmingham
NCT03797378
Modulation of Cerebral Blood Flow Using Quercetin, a Nutritional Supplement
Brigham and Women's Hospital
NCT01376011
REACH OUT: to Reduce High Blood Pressure in the Emergency Department
University of Michigan
NCT02301455
Frequency vs Error Augmentation Training in Acute Physical Therapy Post Stroke
Christine Holmstedt
NCT06042179
HEALS (Healthy Eating And Lifestyle After Stroke)
Los Amigos Research and Education Institute
NCT01550822
Innovative Measures of Speech and Swallowing Dysfunction in Neurological Disorders
Beth Israel Deaconess Medical Center
NCT02118805
Amphetamine-Enhanced Stroke Recovery
Duke University
NCT01905371
Very Intensive Variable Repetitive AmbulatioN Training
Shirley Ryan AbilityLab
NCT02507466
Post-stroke Perturbation Training
Medical University of South Carolina
NCT04855032
Does More Practice Improve Arm Movement After Stroke?
Washington University School of Medicine
NCT01146379
Peri-device Leakage Closure After LAAO
Cardiovascular Center Frankfurt
NCT04590898
Cortical Priming to Optimize Gait Rehabilitation Post Stroke
University of Illinois at Chicago
NCT03492229
Interventional Management of Stroke (IMS) II Study
University of Cincinnati
NCT00243906
Electrical Stimulation for Recovery of Hand Function in Chronic Stroke Survivors
MetroHealth Medical Center
NCT00891319
Perceptual-motor Interaction to Improve Bimanual Coordination After Stroke
Albert Einstein Healthcare Network
NCT03755076
MEditation for Post Stroke Depression
The University of Texas Health Science Center, Houston
NCT03239132
Gait Training For Acute Stroke: Functional Neuromuscular Stimulation (FNS) and Weight Supported Treadmill Training
US Department of Veterans Affairs
NCT00101543
Coordination of Hemiparetic Movement After Post-Stroke Rehabilitation
US Department of Veterans Affairs
NCT00013481
Testing a Positive Psychology-based Intervention for Couples Coping With Stroke
University of Utah
NCT03335358
Stroke Therapy, Education, Prevention: Telemedicine Outpatient Initiative Trial
Oregon Health and Science University
NCT01875328
Translating Intensive Arm Rehabilitation in Stroke to a Telerehabilitation Format
VA Office of Research and Development
NCT02665052
Dose Optimization for Stroke Evaluation
University of Southern California
NCT01749358
Antihypertensive Treatment in Acute Cerebral Hemorrhage
University of Minnesota
NCT00415610
The Intensive Comprehensive Aphasia Program (ICAP)
Shirley Ryan AbilityLab
NCT03514186
Apixaban Versus Warfarin for the Management of Post-operative Atrial Fibrillation
Sanford Health
NCT02889562
Nutrition and Aerobic Exercise in Chronic Stroke
VA Office of Research and Development
NCT02043574
Motor Performance in Chronic Stroke Patients
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00110175
One vs. Two Hand Use After Stroke: Role of Task Requirements
Cleveland State University
NCT03025776
Cognitive Oriented Strategy Training Augmented Rehabilitation (COSTAR) Treatment Approach for Stroke
Washington University School of Medicine
NCT01910454
Deficit Fields for Stroke Recovery
Shirley Ryan AbilityLab
NCT02570256
Transcranial Direct Current Stimulation for Post-stroke Gait Rehab
VA Office of Research and Development
NCT03666533
Quantifying the Role of Sensory Systems Processing in Post-Stroke Walking Recovery
University of Cincinnati
NCT04553198
Sensory Augmentation Methods in Stroke
VA Office of Research and Development
NCT03988400
Use of Transcranial Direct Current Stimulation (tDCS) Coupled With Constraint Induced Movement Therapy in Stroke Patient
Spaulding Rehabilitation Hospital
NCT01143649
TMS as a Biological Marker of Neuroplasticity
University of Pennsylvania
NCT02867670
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 35 |
| Phase 2 | 34 |
| Phase 3 | 7 |
| Phase 4 | 9 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
What is open for Stroke right now
218 recruiting of 456 indexed (48% open).
Phase mix: 16 late (III/IV) vs 69 early (I/II) (early-phase heavy).
Top sponsor: VA Office of Research and Development (27 trials), 9 others listed. 50 shown below, recruiting first. #9 of 28,963 conditions by registered trial count.
How open-enrollment share is computed
Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.
Frequently Asked Questions
How many clinical trials are there for Stroke?
PlainTrial tracks 456 US clinical trials for Stroke, of which 218 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Stroke?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.