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NCT04661891 · ClinicalTrials.gov registry record · NA
Real-time Neuromuscular Control of Exoskeletons
A NA study of Stroke, sponsored by Shirley Ryan AbilityLab.
- Active
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT04661891: Active NA study of Stroke, sponsored by Shirley Ryan AbilityLab.
NCT04661891 is a NA study of Stroke that is active but no longer recruiting, run by Shirley Ryan AbilityLab. The registered enrollment target is 80 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04661891, a NA study of Stroke, is active but no longer recruiting, sponsored by Shirley Ryan AbilityLab.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of this study is to develop a real-time controller for exoskeletons using neural information embedded in human musculature. This controller will consist of an online interface that anticipates human movement based on high-density electromyography (HD-EMG) recordings, and then translates it into functional assistance. This study will be carried out in both healthy participants and participants post-stroke. The researchers will develop an online algorithm (decoder) in currently existing exoskeletons that can extract hundreds of motor unit (MU) spiking activity out of HD-EMG recordings. The MU spiking activity is a train of action potentials coded by its timing of occurrence that gives access to a representative part of the neural code of human movement. The researchers will also develop a command encoder that can anticipate human intent (multi-joint position and force commands) from MU spiking activity to translate the neural information to movement. The researchers will integrate the decoder with the command encoder to showcase the real-time control of multiple joint lower-limb exoskeletons.
Conditions Studied
Interventions
- OTHER Isometric contractions
- OTHER Isokinetic contractions
- DEVICE Dynamic contractions
- DEVICE Isometric contraction with muscle fatigue
- DEVICE Multi-joint functional activities while wearing exoskeleton
Study Locations (1)
Illinois
- Shirley Ryan AbilityLab - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2021-05-05 |
| Est. Completion | 2025-12 |
| Phase | NA |
What the registry record for NCT04661891 still lists
NCT04661891 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 5 interventions - of which Isometric contractions is the first listed.
NCT04661891 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT04661891 about?
NCT04661891 is a clinical study titled "Real-time Neuromuscular Control of Exoskeletons". The purpose of this study is to develop a real-time controller for exoskeletons using neural information embedded in human musculature. This controller will consist of an online interface that anticipates human movement based on high-density electromyography (HD-EMG) recordings, and then translates ...
What is the current status of trial NCT04661891?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2021-05-05. Estimated completion is 2025-12.
What conditions does trial NCT04661891 study?
This clinical trial studies the following conditions: Stroke.
What interventions are being tested in trial NCT04661891?
The interventions under investigation include: Isometric contractions (OTHER), Isokinetic contractions (OTHER), Dynamic contractions (DEVICE), Isometric contraction with muscle fatigue (DEVICE), Multi-joint functional activities while wearing exoskeleton (DEVICE).
Who is sponsoring clinical trial NCT04661891?
This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04661891 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04661891's enrollment target sits among peer trials
80 167th of 454 higher than 282 of 454 other Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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