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NCT04661891 · ClinicalTrials.gov registry record · NA

Real-time Neuromuscular Control of Exoskeletons

A NA study of Stroke, sponsored by Shirley Ryan AbilityLab.

Active
Registry status
NA
Development phase
80
Enrollment target
1
Study location

NCT04661891: Active NA study of Stroke, sponsored by Shirley Ryan AbilityLab.

NCT04661891 is a NA study of Stroke that is active but no longer recruiting, run by Shirley Ryan AbilityLab. The registered enrollment target is 80 participants, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04661891, a NA study of Stroke, is active but no longer recruiting, sponsored by Shirley Ryan AbilityLab.

ACTIVE NOT RECRUITING
Registry status
NA
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to develop a real-time controller for exoskeletons using neural information embedded in human musculature. This controller will consist of an online interface that anticipates human movement based on high-density electromyography (HD-EMG) recordings, and then translates it into functional assistance. This study will be carried out in both healthy participants and participants post-stroke. The researchers will develop an online algorithm (decoder) in currently existing exoskeletons that can extract hundreds of motor unit (MU) spiking activity out of HD-EMG recordings. The MU spiking activity is a train of action potentials coded by its timing of occurrence that gives access to a representative part of the neural code of human movement. The researchers will also develop a command encoder that can anticipate human intent (multi-joint position and force commands) from MU spiking activity to translate the neural information to movement. The researchers will integrate the decoder with the command encoder to showcase the real-time control of multiple joint lower-limb exoskeletons.

Conditions Studied

Interventions

  • OTHER Isometric contractions
  • OTHER Isokinetic contractions
  • DEVICE Dynamic contractions
  • DEVICE Isometric contraction with muscle fatigue
  • DEVICE Multi-joint functional activities while wearing exoskeleton

Study Locations (1)

Illinois

  • Shirley Ryan AbilityLab - Chicago

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2021-05-05
Est. Completion 2025-12
Phase NA

Sponsor

Shirley Ryan AbilityLab

138 total trials

What the Registry Record Tells You About NCT04661891

The ClinicalTrials.gov registry entry for NCT04661891 describes a study currently listed as active not recruiting, categorized as NA. The registered enrollment target is 80 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 12,016-participant average among 454 other Stroke trials with a reported enrollment target (99% lower). The listed sponsor is Shirley Ryan AbilityLab, which has 138 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Stroke appearing as the primary indexed condition, and to 5 interventions - of which Isometric contractions is the first listed.

NCT04661891 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT04661891 about?

NCT04661891 is a clinical study titled "Real-time Neuromuscular Control of Exoskeletons". The purpose of this study is to develop a real-time controller for exoskeletons using neural information embedded in human musculature. This controller will consist of an online interface that anticipates human movement based on high-density electromyography (HD-EMG) recordings, and then translates ...

What is the current status of trial NCT04661891?

This trial is currently active not recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2021-05-05. Estimated completion is 2025-12.

What conditions does trial NCT04661891 study?

This clinical trial studies the following conditions: Stroke.

What interventions are being tested in trial NCT04661891?

The interventions under investigation include: Isometric contractions (OTHER), Isokinetic contractions (OTHER), Dynamic contractions (DEVICE), Isometric contraction with muscle fatigue (DEVICE), Multi-joint functional activities while wearing exoskeleton (DEVICE).

Who is sponsoring clinical trial NCT04661891?

This trial is sponsored by Shirley Ryan AbilityLab, which has 138 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04661891 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.