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ClinicalTrials.gov 6 recruiting now early-phase tilt small index

Stage III Breast Cancer: early-phase trial registry

6 of 18 indexed Stage III Breast Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #953 of 28,707 conditions by registered trial count.

18 US clinical trials · 6 currently recruiting · #953 of 28,707 conditions by registered trial count

Stage III Breast Cancer: 18 US clinical trials tracked, 6 recruiting.

Stage III Breast Cancer is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Dana-Farber Cancer Institute, running 4 of these trials.

Enrollment posture brief

Registry condition stage-iii-breast-cancer

OPEN 6 | RECR 33% | LATE 2 | EARLY 9 | RANK #953 | SPON 4

Nearest open-share peer: Adherence, Treatment (33% recruiting · 6 trials)

Stage III Breast Cancer (thi…33%Arrhythmias, Cardiac27.8%Androgenetic Alopecia16.7%Anemia, Sickle Cell16.7%Acquired Immunodeficiency Sy5.6%
Open-enrollment share among volume-matched conditions near Stage III Breast Cancer

Stage III Breast Cancer lists 6 open slots (33% of 18 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Stage III Breast Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Stage III Breast Cancer is recruiting below its size-band peers.

    6 of 18 indexed trials (33.3%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Stage III Breast Cancer research.

    Dana-Farber Cancer Institute accounts for 4 of 18 trials (22.2%). 12 distinct sponsors appear on at least one study for this condition label.

  3. Most Stage III Breast Cancer trials plan to enrol fewer than 100 people.

    Median target enrolment is 62 among the 18 trials that report a genuine target (sentinel values excluded). 12 of those (66.7%) plan for fewer than 100 participants.

  4. Stage III Breast Cancer research is mostly interventional.

    18 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 26Phase 31Phase 41

Open and recent trials

18 total, page 1 of 1

RECRUITING NA 270 participants

TeleHealth Resistance Exercise Intervention to Preserve Dose Intensity and Vitality in Elder Breast Cancer Patients

Dana-Farber Cancer Institute

NCT05535192

RECRUITING Phase 2 150 participants

Avelumab With Binimetinib, Sacituzumab Govitecan, or Liposomal Doxorubicin in Treating Stage IV or Unresectable, Recurrent Triple Negative Breast Cancer

Laura Huppert, MD, BA

NCT03971409

RECRUITING NA 110 participants

Improving Exercise Capacity With a Tailored Physical Activity Intervention

Wake Forest University Health Sciences

NCT05595577

RECRUITING Phase 2 88 participants

Trastuzumab Deruxtecan Alone or in Combination With Anastrozole for the Treatment of Early Stage HER2 Low, Hormone Receptor Positive Breast Cancer

Jonsson Comprehensive Cancer Center

NCT04553770

RECRUITING Phase 4 60 participants

A Study of Revaree Plus in People With Breast Cancer

Memorial Sloan Kettering Cancer Center

NCT07042581

RECRUITING NA 30 participants

A Study of Disappearing Markers for Daily Radiation Treatment Delivery for Breast Cancer Patients.

Barbara Ann Karmanos Cancer Institute

NCT07095114

ACTIVE NOT RECRUITING Phase 3 415 participants

Platinum in Treating Patients With Residual Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy

ECOG-ACRIN Cancer Research Group

NCT02445391

ACTIVE NOT RECRUITING Phase 2 174 participants

MARGetuximab Or Trastuzumab (MARGOT)

Dana-Farber Cancer Institute

NCT04425018

ACTIVE NOT RECRUITING Phase 2 164 participants

T-DM1+Pertuzumab in Pre-OP Early-Stage HER2+ BRCA

Dana-Farber Cancer Institute

NCT02326974

ACTIVE NOT RECRUITING Phase 2 62 participants

Niraparib + Dostarlimab In BRCA Mutated Breast Cancer

Dana-Farber Cancer Institute

NCT04584255

ACTIVE NOT RECRUITING Phase 2 48 participants

Acupuncture Pilot Study for Cancer-related Cognitive Function

Memorial Sloan Kettering Cancer Center

NCT04007770

ACTIVE NOT RECRUITING Phase 1 42 participants

Vaccine Therapy in Treating Patients With HER2-Negative Stage III-IV Breast Cancer

University of Washington

NCT02157051

ACTIVE NOT RECRUITING NA 33 participants

Researching the Effect of Exercise on Cancer

Memorial Sloan Kettering Cancer Center

NCT04589468

ACTIVE NOT RECRUITING Early Phase 1 31 participants

HER2 Directed Dendritic Cell Vaccine During Neoadjuvant Therapy of HER2+Breast Cancer

H. Lee Moffitt Cancer Center and Research Institute

NCT03387553

COMPLETED NA 81 participants

Ask Questions (ASQ):Implementation of a Communication Intervention

Barbara Ann Karmanos Cancer Institute

NCT05025748

COMPLETED Phase 1 18 participants

4-1BB Agonist Monoclonal Antibody PF-05082566 With Trastuzumab Emtansine or Trastuzumab in Treating Patients With Advanced HER2-Positive Breast Cancer

George W. Sledge Jr.

NCT03364348

COMPLETED NA 17 participants

Living Well After Breast Surgery

University of Texas at Austin

NCT03834532

COMPLETED NA 4 participants

Aerobic and Strength Training Exercise in Improving Fitness and Arm Health During and After Radiation Therapy in Patients With Stage II-III Breast Cancer

Ohio State University Comprehensive Cancer Center

NCT03102866

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 6
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Stage III Breast Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Pertuzumab Drug
2 trials
Trastuzumab Drug
2 trials
Educational website Other
1 trials
Breast reconstruction decision aid Other
1 trials
Ado-Trastuzumab Emtansine Drug
1 trials
Curative Surgery Procedure
1 trials
Dendritic Cell Vaccine (DC1) Biological
1 trials
Utomilumab Drug
1 trials

US sites by state

Facility locations filed on Stage III Breast Cancer trials. A trial with sites in several states counts in each.

Massachusetts 6 trials
California 5 trials
New York 4 trials
Washington 3 trials
Texas 3 trials
Tennessee 3 trials
Pennsylvania 3 trials
New Jersey 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Stage III Breast Cancer page

18 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Stage III Breast Cancer condition card totals 18 registered trials; most-linked intervention Pertuzumab; top US site state Massachusetts. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.