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NCT04589468 · ClinicalTrials.gov registry record · NA
Researching the Effect of Exercise on Cancer
A NA study of Breast Cancer and Prostate Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
- Active
- Registry status
- NA
- Development phase
- 33
- Enrollment target
- 8
- Study locations
NCT04589468: Active NA study of Breast Cancer and Prostate Cancer, sponsored by Memorial Sloan Kettering Cancer Center.
NCT04589468 is a NA study of Breast Cancer and Prostate Cancer that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 33 participants, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower). The trial reports 8 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04589468, a NA study of Breast Cancer and Prostate Cancer, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 33 participants
- Enrollment target
- 8
- Study locations
Study Summary
Researchers think that exercise may be able to prevent cancer from coming back by lowering ctDNA levels. The purpose of this study is to explore how aerobic exercise (exercise that stimulates and strengthens the heart and lungs and improves the body's use of oxygen) can reduce the level of ctDNA found in the blood. During the study, the highest level of exercise that is practical, is safe, and has positive effects on the body that may prevent the return of cancer (including a decrease in ctDNA levels) will be found. Each level of exercise tested will be a certain number of minutes each week. Once the best level of exercise is found, it will be tested further in a new group of participants. All participants in this study will have been previously treated for breast, prostate, or colorectal cancer.
Primary Outcome
Using an adaptive phase 1 (non-randomized) design, non-exercising (i.e., \<60 mins/wk of moderate or vigorous exercise) post-treatment patients with primary breast, prostate, or colorectal cancer and detectable ctDNA (n=50) will be administered one of five escalating dose levels.
Conditions Studied
Interventions
- OTHER Exercise
Study Locations (8)
New York
- Memorial Sloan Kettering Commack (Limited Protocol Activities) - Commack
- Memorial Sloan Kettering Westchester (Limited Protocol Activities) - Harrison
- Memorial Sloan Kettering Cancer Center - New York
- Memorial Sloan Kettering Nassau (Limited Protocol Activities) - Uniondale
New Jersey
- Memorial Sloan Kettering Basking Ridge (Limited Protocol Activities) - Basking Ridge
- Memorial Sloan Kettering Monmouth (Limited Protocol Activities) - Middletown
- Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale
California
- Natera, Inc. (Data or Specimen Analysis Only) - San Carlos
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 33 participants |
| Start Date | 2020-10-02 |
| Est. Completion | 2026-10-02 |
| Phase | NA |
What the registry record for NCT04589468 still lists
NCT04589468 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 33 participants, a relatively small participant target, below the 2,803-participant average among 1,224 other Breast Cancer trials with a reported enrollment target (99% lower).
The record links to 10 conditions, with Breast Cancer appearing as the primary indexed condition, and to 1 intervention - of which Exercise is the first listed.
NCT04589468 lists 8 locations in 3 states (New York, New Jersey, California).
Frequently Asked Questions
What is clinical trial NCT04589468 about?
NCT04589468 is a clinical study titled "Researching the Effect of Exercise on Cancer". Researchers think that exercise may be able to prevent cancer from coming back by lowering ctDNA levels. The purpose of this study is to explore how aerobic exercise (exercise that stimulates and strengthens the heart and lungs and improves the body's use of oxygen) can reduce the level of ctDNA fou...
What is the current status of trial NCT04589468?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 33 participants. The study started on 2020-10-02. Estimated completion is 2026-10-02.
What conditions does trial NCT04589468 study?
This clinical trial studies the following conditions: Breast Cancer, Prostate Cancer, Colorectal Cancer, Stage II Breast Cancer, Stage III Breast Cancer.
What interventions are being tested in trial NCT04589468?
The interventions under investigation include: Exercise (OTHER).
Who is sponsoring clinical trial NCT04589468?
This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04589468 being conducted?
This trial has 8 study locations across California, New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04589468's enrollment target sits among peer trials
33 935th of 1224 higher than 285 of 1,224 other Breast Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Breast Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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