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ClinicalTrials.gov 13 recruiting now official registry

Spinal Fusion clinical trials

13 of 20 indexed Spinal Fusion trials are currently recruiting.

20 US clinical trials · 13 currently recruiting

Spinal Fusion is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Columbia University, running 2 of these trials.

The research picture

Spinal Fusion has 20 registered US clinical trials, 13 of them open to new participants right now, about 65% of the total.

13
recruiting participants now
65%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
2
top sponsor: Columbia University
Phase 12Phase 22Phase 31Phase 41

Active & Recent Trials

20 total, page 1 of 1

RECRUITING 5,000 participants

Prospective SPINE Registry

Xtant Medical

NCT04176562

RECRUITING 1,244 participants

Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions

AO Foundation, AO Spine

NCT06368245

RECRUITING 1,000 participants

Personalized Spine Study Group (PSSG) Registry

University of Colorado, Denver

NCT04601363

RECRUITING Phase 3 278 participants

A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain

University of California, San Francisco

NCT05010148

RECRUITING NA 275 participants

Kids With Iron Deficiency and Scoliosis

Columbia University

NCT06042699

RECRUITING NA 128 participants

Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine

Boston Children's Hospital

NCT06471348

RECRUITING Phase 2 120 participants

IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study

Columbia University

NCT07217873

RECRUITING Phase 2 96 participants

Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion Surgery

Hospital for Special Surgery, New York

NCT03841058

RECRUITING NA 80 participants

Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

University of California, Los Angeles

NCT06282770

RECRUITING Phase 4 60 participants

Safety and Efficacy of Subdermal Betadine During Posterior Spinal Fusion

Akron Children's Hospital

NCT06744907

RECRUITING NA 50 participants

Pulse-Width Modulation

Dartmouth-Hitchcock Medical Center

NCT06120231

RECRUITING NA 50 participants

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

Alexander T. Yahanda

NCT07218133

RECRUITING Early Phase 1 50 participants

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

University of Iowa

NCT05461092

ACTIVE NOT RECRUITING 330 participants

Artoss Prospective Spine Registry Outcomes

Artoss

NCT04439032

ACTIVE NOT RECRUITING 200 participants

Pelvic Fixation and Fusion During Multilevel Spinal Surgery

SI-BONE

NCT05640908

ACTIVE NOT RECRUITING NA 108 participants

Lumbar Fusion With Porous Versus Non-Porous Cages

Francis Farhadi

NCT05583864

COMPLETED 50 participants

Thromboelastography-Guided Fluid Management in Spinal Surgery

Mayo Clinic

NCT03999086

COMPLETED NA 31 participants

Alvimopan and Ileus in PSF

Washington University School of Medicine

NCT02218190

COMPLETED 17 participants

Impact of Body Habitus (Arm Span and Abdominal Girth) on Activities of Daily Living (ADL)

Duke University

NCT04037059

COMPLETED Phase 1 15 participants

PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive Surgery

Pacira Pharmaceuticals

NCT02985762

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2
Phase 3 1
Phase 4 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Spinal Fusion Trial Landscape

20 indexed Spinal Fusion studies · 13 recruiting (65%).

Phase mix: 2 late (III/IV) vs 4 early (I/II).

Top sponsor: Columbia University (2 trials), 9 others listed. 20 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Spinal Fusion?

PlainTrial tracks 20 US clinical trials for Spinal Fusion, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Spinal Fusion?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.