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ClinicalTrials.gov 13 recruiting now early-phase tilt

Spinal Fusion: early-phase trial registry

13 of 20 indexed Spinal Fusion trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #848 of 28,707 conditions by registered trial count.

20 US clinical trials · 13 currently recruiting · #848 of 28,707 conditions by registered trial count

Spinal Fusion: 20 US clinical trials tracked, 13 recruiting.

Spinal Fusion is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Columbia University, running 2 of these trials.

Enrollment posture brief

Registry condition spinal-fusion

OPEN 13 | RECR 65% | LATE 2 | EARLY 4 | RANK #848 | SPON 2

Nearest open-share peer: Focal Segmental Glomerulosclerosis (65% recruiting · 20 trials)

Spinal Fusion (this)65%Advanced or Metastatic Solid55%ALS50%Abdominal Pain25%Acute Myocardial Infarction25%
Open-enrollment share among volume-matched conditions near Spinal Fusion

Spinal Fusion lists 13 open slots (65% of 20 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Spinal Fusion on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Spinal Fusion is recruiting above its size-band peers.

    13 of 20 indexed trials (65%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Spinal Fusion trials is spread across many organizations.

    Columbia University accounts for 2 of 20 trials (10%). 19 distinct sponsors appear on at least one study for this condition label.

  3. Typical Spinal Fusion enrolment sits around 108 participants.

    Median target enrolment is 108 among the 20 trials that report a genuine target (sentinel values excluded). 10 of those (50%) plan for fewer than 100 participants.

  4. Spinal Fusion splits between interventional and observational designs.

    13 interventional and 7 observational studies make up this index (65% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 22Phase 31Phase 41

Open and recent trials

20 total, page 1 of 1

RECRUITING 5,000 participants

Prospective SPINE Registry

Xtant Medical

NCT04176562

RECRUITING 1,244 participants

Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions

AO Foundation, AO Spine

NCT06368245

RECRUITING 1,000 participants

Personalized Spine Study Group (PSSG) Registry

University of Colorado, Denver

NCT04601363

RECRUITING Phase 3 278 participants

A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain

University of California, San Francisco

NCT05010148

RECRUITING NA 275 participants

Kids With Iron Deficiency and Scoliosis

Columbia University

NCT06042699

RECRUITING NA 128 participants

Postoperative Pain Control in AIS Using Liposomal Bupivacaine vs. 0.25% Bupivacaine With Epinephrine

Boston Children's Hospital

NCT06471348

RECRUITING Phase 2 120 participants

IntraVenous Iron in Kids With Iron Deficiency and Scoliosis Study

Columbia University

NCT07217873

RECRUITING Phase 2 96 participants

Abaloparatide vs. Placebo in Post-Menopausal Women and Abaloparatide in Men Receiving Initial Spinal Fusion Surgery

Hospital for Special Surgery, New York

NCT03841058

RECRUITING NA 80 participants

Photobiomodulation for Lower Back Pain Post Spinal Fusion and Decompression Surgery

University of California, Los Angeles

NCT06282770

RECRUITING Phase 4 60 participants

Safety and Efficacy of Subdermal Betadine During Posterior Spinal Fusion

Akron Children's Hospital

NCT06744907

RECRUITING NA 50 participants

Pulse-Width Modulation

Dartmouth-Hitchcock Medical Center

NCT06120231

RECRUITING NA 50 participants

Trans-Auricular Stimulation for Postoperative Inflammation in Spine Surgery

Alexander T. Yahanda

NCT07218133

RECRUITING Early Phase 1 50 participants

Regional Nerve Blocks to Improve Analgesia and Recovery in Older Adults Undergoing Spinal Fusion

University of Iowa

NCT05461092

ACTIVE NOT RECRUITING 330 participants

Artoss Prospective Spine Registry Outcomes

Artoss

NCT04439032

ACTIVE NOT RECRUITING 200 participants

Pelvic Fixation and Fusion During Multilevel Spinal Surgery

SI-BONE

NCT05640908

ACTIVE NOT RECRUITING NA 108 participants

Lumbar Fusion With Porous Versus Non-Porous Cages

Francis Farhadi

NCT05583864

COMPLETED 50 participants

Thromboelastography-Guided Fluid Management in Spinal Surgery

Mayo Clinic

NCT03999086

COMPLETED NA 31 participants

Alvimopan and Ileus in PSF

Washington University School of Medicine

NCT02218190

COMPLETED 17 participants

Impact of Body Habitus (Arm Span and Abdominal Girth) on Activities of Daily Living (ADL)

Duke University

NCT04037059

COMPLETED Phase 1 15 participants

PK Study of EXPAREL in Subjects Undergoing Open Spinal Fusion or Reconstructive Surgery

Pacira Pharmaceuticals

NCT02985762

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 2
Phase 3 1
Phase 4 1

Named interventions

Most-linked intervention names on Spinal Fusion records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
3 trials
Intervention Procedure
1 trials
NanoBone Bone Graft Substitute Other
1 trials
iFuse Bedrock Granite Implant System Device
1 trials
PROTI 360 Titanium-Coated PEEK Spinal Cage Device
1 trials
CONDUIT Porous Titanium Spinal Cage Device
1 trials
Ferric carboxymaltose IV Drug
1 trials
Numerical Rating Score (NRS) Other
1 trials

US sites by state

Facility locations filed on Spinal Fusion trials. A trial with sites in several states counts in each.

New York 5 trials
California 4 trials
Ohio 3 trials
Missouri 3 trials
North Carolina 2 trials
Minnesota 2 trials
Maryland 2 trials
Florida 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Spinal Fusion page

20 registered trials, 13 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Spinal Fusion condition card totals 20 registered trials; most-linked intervention Placebo; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.