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NCT00500812 · ClinicalTrials.gov registry record · Phase 1
A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries
A Phase 1 study of Spinal Cord Injury, sponsored by Vertex Pharmaceuticals Incorporated.
- Completed
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
- 8
- Study locations
NCT00500812: Completed Phase 1 study of Spinal Cord Injury, sponsored by Vertex Pharmaceuticals Incorporated.
NCT00500812 is a Phase 1 study of Spinal Cord Injury that has completed, run by Vertex Pharmaceuticals Incorporated. The registered enrollment target is 48 participants, below the 86-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target (44% lower). The trial reports 8 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00500812, a Phase 1 study of Spinal Cord Injury, has completed, sponsored by Vertex Pharmaceuticals Incorporated.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
- 8
- Study locations
Study Summary
This trial is a multi-center, open-label, dose-escalation study designed to evaluate the safety, tolerability and pharmacokinetics of Cethrin in two types of spinal cord injury patients: those with a complete cervical injury or a complete thoracic injury. Dose levels from 0.3 mg - 9 mg of Cethrin will be administered.
Conditions Studied
Interventions
- DRUG Cethrin
Study Locations (8)
Ontario
- Sunnybrooke Health Sciences Centre - Toronto
- Toronto Western Hospital - Toronto
Arizona
- St. Joseph's Hospital & Medical Center - Phoenix
Ohio
- University of Cincinnati Mayfield Clinic and Spine Institute - Cincinnati
Pennsylvania
- Thomas Jefferson University Hospital - Philadelphia
Virginia
- Univ.of Virginia Health System - Charlottesville
Washington
- University of Washington Harborview Medical Center - Seattle
Quebec
- Hopital du Sacre-Coeur de Montreal - Montreal
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2005-02 |
| Est. Completion | 2009-02 |
| Phase | Phase 1 |
What the finished NCT00500812 record still lists
NCT00500812 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 86-participant average among 99 other Spinal Cord Injury trials with a reported enrollment target (44% lower).
The record links to 1 condition, with Spinal Cord Injury appearing as the primary indexed condition, and to 1 intervention - of which Cethrin is the first listed.
NCT00500812 lists 8 locations in 7 states (Ontario, Arizona, Ohio).
Frequently Asked Questions
What is clinical trial NCT00500812 about?
NCT00500812 is a clinical study titled "A Safety Study for Cethrin (BA-210) in the Treatment of Acute Thoracic and Cervical Spinal Cord Injuries". This trial is a multi-center, open-label, dose-escalation study designed to evaluate the safety, tolerability and pharmacokinetics of Cethrin in two types of spinal cord injury patients: those with a complete cervical injury or a complete thoracic injury. Dose levels from 0.3 mg - 9 mg of Cethrin wi...
What is the current status of trial NCT00500812?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2005-02. Estimated completion is 2009-02.
What conditions does trial NCT00500812 study?
This clinical trial studies the following conditions: Spinal Cord Injury.
What interventions are being tested in trial NCT00500812?
The interventions under investigation include: Cethrin (DRUG).
Who is sponsoring clinical trial NCT00500812?
This trial is sponsored by Vertex Pharmaceuticals Incorporated, which has 191 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00500812 being conducted?
This trial has 8 study locations across Arizona, Ohio, Pennsylvania, Virginia, Washington. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Spinal Cord Injury
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00500812's enrollment target sits among peer trials
48 36th of 99 higher than 63 of 99 other Spinal Cord Injury trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Spinal Cord Injury trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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