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NCT03968900 · ClinicalTrials.gov registry record · NA
Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal
A NA study of Smoking and Nicotine Dependence, sponsored by University of Alabama at Birmingham.
- Active
- Registry status
- NA
- Development phase
- 50
- Enrollment target
- 1
- Study location
NCT03968900: Active NA study of Smoking and Nicotine Dependence, sponsored by University of Alabama at Birmingham.
NCT03968900 is a NA study of Smoking and Nicotine Dependence that is active but no longer recruiting, run by University of Alabama at Birmingham. The registered enrollment target is 50 participants, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (89% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03968900, a NA study of Smoking and Nicotine Dependence, is active but no longer recruiting, sponsored by University of Alabama at Birmingham.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 50 participants
- Enrollment target
- 1
- Study location
Study Summary
The number one preventable cause of death in the world is tobacco use. Cigarette smoking in particular, costs an estimated $300 billion due to expenses related to medical care and lost productivity. Despite similar smoking prevalence rates, blacks suffer disproportionately from smoking-related harms compared to whites.Sleep disparities such as shortened sleep duration, shorter circadian periodicity, earlier chronotype, and increased variability of sleep timing have been reported more frequently in blacks compared to whites. Given that poor sleep quality predicts relapse from smoking cessation programs, particularly among socioeconomically disadvantaged adults, sleep deficiencies and irregular timing of sleep may impact smoking craving and withdrawal symptoms over the course of the 24-hour day. Surprisingly, few studies have examined these temporal patterns of smoking and craving, and none with regard to sleep disruption, chronotype or racial disparities. A better understanding of these factors may explain heterogeneity within the smoking population, especially in minorities. Thus, the purpose of this proposal is to test the central hypothesis that the impact of chronotype and impaired sleep on cigarette usage as well as smoking dependence, urge/craving, and withdrawal depends on race.
Primary Outcome
A 13-item scale that assesses behaviors, such as variability in wake-time, timing of physical activity, and substance use, that comprise sleep hygiene. Higher values indicate worse sleep hygiene. The minimum value is 0, and the maximum value is 52.
Conditions Studied
Interventions
- BEHAVIORAL Sleep restriction condition
- BEHAVIORAL Sleep extension condition
Study Locations (1)
Alabama
- University of Alabama, Birmingham - Birmingham
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 50 participants |
| Start Date | 2021-01-01 |
| Est. Completion | 2026-08-01 |
| Phase | NA |
What the registry record for NCT03968900 still lists
NCT03968900 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 50 participants, a relatively small participant target, below the 455-participant average among 123 other Smoking trials with a reported enrollment target (89% lower).
The record links to 3 conditions, with Smoking appearing as the primary indexed condition, and to 2 interventions - of which Sleep restriction condition is the first listed.
NCT03968900 reports a single indexed study location in Alabama.
Frequently Asked Questions
What is clinical trial NCT03968900 about?
NCT03968900 is a clinical study titled "Racial Differences in Circadian and Sleep Mechanisms for Nicotine Dependence, Craving, and Withdrawal". The number one preventable cause of death in the world is tobacco use. Cigarette smoking in particular, costs an estimated $300 billion due to expenses related to medical care and lost productivity. Despite similar smoking prevalence rates, blacks suffer disproportionately from smoking-related harms...
What is the current status of trial NCT03968900?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 50 participants. The study started on 2021-01-01. Estimated completion is 2026-08-01.
What conditions does trial NCT03968900 study?
This clinical trial studies the following conditions: Smoking, Nicotine Dependence, Sleep Disturbance.
What interventions are being tested in trial NCT03968900?
The interventions under investigation include: Sleep restriction condition (BEHAVIORAL), Sleep extension condition (BEHAVIORAL).
Who is sponsoring clinical trial NCT03968900?
This trial is sponsored by University of Alabama at Birmingham, which has 1,160 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03968900 being conducted?
This trial has 1 study location across Alabama. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Smoking
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03968900's enrollment target sits among peer trials
50 95th of 123 higher than 28 of 123 other Smoking trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Smoking trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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