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ClinicalTrials.gov 12 recruiting now official registry

Rheumatoid Arthritis (RA) clinical trials

12 of 18 indexed Rheumatoid Arthritis (RA) trials are currently recruiting.

18 US clinical trials · 12 currently recruiting

Rheumatoid Arthritis (RA) is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 2 of these trials.

The research picture

Rheumatoid Arthritis (RA) has 18 registered US clinical trials, 12 of them open to new participants right now, about 67% of the total.

12
recruiting participants now
67%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: Brigham and Women's Hospital
Phase 11Phase 25Phase 31

Active & Recent Trials

18 total, page 1 of 1

RECRUITING NA 285 participants

Dose Response of Exercise for Arthritis Management

University of South Carolina

NCT06880653

RECRUITING NA 250 participants

Healthier: Health Coaching for People With Rheumatoid Arthritis to Improve Mental Well-Being

Weill Medical College of Cornell University

NCT07222696

RECRUITING Phase 2 240 participants

A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis

SynAct Pharma Aps

NCT06671054

RECRUITING Phase 1 134 participants

A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis

Eli Lilly and Company

NCT07258849

RECRUITING 120 participants

The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study

Brigham and Women's Hospital

NCT07315997

RECRUITING NA 100 participants

Comparative Effectiveness of Primary Care Providers Trained in Rheumatoid Arthritis Management Versus Rheumatologist Care: A Randomized Controlled Trial

St. Lawrence Health System

NCT07034196

RECRUITING Phase 2 90 participants

AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.

Artiva Biotherapeutics

NCT06991114

RECRUITING 70 participants

A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101

Kyverna Therapeutics

NCT07403188

RECRUITING NA 60 participants

At-home Ultrasound Localized Therapy for Rheumatoid Arthritis Study [At-home ULTRA Study]

SecondWave Systems

NCT07163221

RECRUITING NA 50 participants

Probiotics in Adults With Rheumatoid Arthritis

Ancilia Biosciences

NCT07304505

RECRUITING Phase 2 40 participants

Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis

Surf Therapeutics

NCT07293871

RECRUITING 36 participants

A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic

Sonoma Biotherapeutics

NCT07123038

ACTIVE NOT RECRUITING 1,500 participants

The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis

Sequenom

NCT03631225

ACTIVE NOT RECRUITING NA 1,325 participants

A Trial of Academic Detailing to Promote Prescribing of Biosimilars

Brigham and Women's Hospital

NCT07221890

ACTIVE NOT RECRUITING NA 40 participants

Food Trial to Evaluate the Kinetics of the Medical Foods SBD111 and SBD121 Persistence in Healthy Adults

Solarea Bio

NCT06614166

COMPLETED Phase 3 119 participants

Phase IIIB Subcutaneous Abatacept Monotherapy Study

Bristol-Myers Squibb

NCT00547521

COMPLETED Phase 2 49 participants

Comparison of Methotrexate (MTX) and the VIBEX™ MTX Device

Antares Pharma

NCT01618968

COMPLETED Phase 2 48 participants

A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ABBV-3373 in Participants With Moderate to Severe Rheumatoid Arthritis (RA)

AbbVie

NCT03823391

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 5
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Rheumatoid Arthritis (RA) Trial Landscape

18 indexed Rheumatoid Arthritis (RA) studies · 12 recruiting (67%).

Phase mix: 1 late (III/IV) vs 6 early (I/II).

Top sponsor: Brigham and Women's Hospital (2 trials), 9 others listed. 18 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Rheumatoid Arthritis (RA)?

PlainTrial tracks 18 US clinical trials for Rheumatoid Arthritis (RA), of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Rheumatoid Arthritis (RA)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.