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Rheumatoid Arthritis (RA) clinical trials
12 of 18 indexed Rheumatoid Arthritis (RA) trials are currently recruiting.
18 US clinical trials · 12 currently recruiting
Rheumatoid Arthritis (RA) is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 2 of these trials.
The research picture
Rheumatoid Arthritis (RA) has 18 registered US clinical trials, 12 of them open to new participants right now, about 67% of the total.
- 12
- recruiting participants now
- 67%
- of trials open to enrollment
- 1
- in Phase 3–4 (later-stage)
- 2
- top sponsor: Brigham and Women's Hospital
Active & Recent Trials
18 total, page 1 of 1
Dose Response of Exercise for Arthritis Management
University of South Carolina
NCT06880653
Healthier: Health Coaching for People With Rheumatoid Arthritis to Improve Mental Well-Being
Weill Medical College of Cornell University
NCT07222696
A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis
SynAct Pharma Aps
NCT06671054
A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis
Eli Lilly and Company
NCT07258849
The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study
Brigham and Women's Hospital
NCT07315997
Comparative Effectiveness of Primary Care Providers Trained in Rheumatoid Arthritis Management Versus Rheumatologist Care: A Randomized Controlled Trial
St. Lawrence Health System
NCT07034196
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Artiva Biotherapeutics
NCT06991114
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Kyverna Therapeutics
NCT07403188
At-home Ultrasound Localized Therapy for Rheumatoid Arthritis Study [At-home ULTRA Study]
SecondWave Systems
NCT07163221
Probiotics in Adults With Rheumatoid Arthritis
Ancilia Biosciences
NCT07304505
Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis
Surf Therapeutics
NCT07293871
A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic
Sonoma Biotherapeutics
NCT07123038
The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis
Sequenom
NCT03631225
A Trial of Academic Detailing to Promote Prescribing of Biosimilars
Brigham and Women's Hospital
NCT07221890
Food Trial to Evaluate the Kinetics of the Medical Foods SBD111 and SBD121 Persistence in Healthy Adults
Solarea Bio
NCT06614166
Phase IIIB Subcutaneous Abatacept Monotherapy Study
Bristol-Myers Squibb
NCT00547521
Comparison of Methotrexate (MTX) and the VIBEX™ MTX Device
Antares Pharma
NCT01618968
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ABBV-3373 in Participants With Moderate to Severe Rheumatoid Arthritis (RA)
AbbVie
NCT03823391
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 5 |
| Phase 3 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Rheumatoid Arthritis (RA) Trial Landscape
18 indexed Rheumatoid Arthritis (RA) studies · 12 recruiting (67%).
Phase mix: 1 late (III/IV) vs 6 early (I/II).
Top sponsor: Brigham and Women's Hospital (2 trials), 9 others listed. 18 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Rheumatoid Arthritis (RA)?
PlainTrial tracks 18 US clinical trials for Rheumatoid Arthritis (RA), of which 12 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Rheumatoid Arthritis (RA)?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.