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Rheumatoid Arthritis (RA): early-phase trial registry
12 of 18 indexed Rheumatoid Arthritis (RA) trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #953 of 28,707 conditions by registered trial count.
18 US clinical trials · 12 currently recruiting · #953 of 28,707 conditions by registered trial count
Rheumatoid Arthritis (RA): 18 US clinical trials tracked, 12 recruiting.
Rheumatoid Arthritis (RA) is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 12 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Brigham and Women's Hospital, running 2 of these trials.
Enrollment posture brief
Registry condition rheumatoid-arthritis-ra
OPEN 12 | RECR 67% | LATE 1 | EARLY 6 | RANK #953 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Acute Hypoxemic Respiratory Failure (67% recruiting · 6 trials)
Rheumatoid Arthritis (RA) lists 12 open slots (67% of 18 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Rheumatoid Arthritis (RA) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Rheumatoid Arthritis (RA) is recruiting above its size-band peers.
12 of 18 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Rheumatoid Arthritis (RA) trials is spread across many organizations.
Brigham and Women's Hospital accounts for 2 of 18 trials (11.1%). 17 distinct sponsors appear on at least one study for this condition label.
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Typical Rheumatoid Arthritis (RA) enrolment sits around 100 participants.
Median target enrolment is 100 among the 18 trials that report a genuine target (sentinel values excluded). 9 of those (50%) plan for fewer than 100 participants.
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Rheumatoid Arthritis (RA) research is mostly interventional.
14 interventional and 4 observational studies make up this index (77.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
18 total, page 1 of 1
Dose Response of Exercise for Arthritis Management
University of South Carolina
NCT06880653
Healthier: Health Coaching for People With Rheumatoid Arthritis to Improve Mental Well-Being
Weill Medical College of Cornell University
NCT07222696
A Dose Response Study to Evaluate the Efficacy and Safety of Oral AP1189 Administered in Disease-Modifying Anti-Rheumatic Drug (DMARD) naïve Participants Participants With Early Rheumatoid Arthritis
SynAct Pharma Aps
NCT06671054
A Study of LY4213663 in Healthy Participants and Participants With Rheumatoid Arthritis
Eli Lilly and Company
NCT07258849
The Coronary Artery Calcium and Troponins in Rheumatoid Arthritis (CAT-RA) Study
Brigham and Women's Hospital
NCT07315997
Comparative Effectiveness of Primary Care Providers Trained in Rheumatoid Arthritis Management Versus Rheumatologist Care: A Randomized Controlled Trial
St. Lawrence Health System
NCT07034196
AlloNK®, an Allogeneic Non-genetically Modified, Cord Blood-derived NK Cell Therapy, in Combination With Rituximab, Studied in Relapsing Forms of B-cell Dependent Rheumatologic Diseases.
Artiva Biotherapeutics
NCT06991114
A Long-Term Follow-Up Study for Participants Previously Treated With KYV-101
Kyverna Therapeutics
NCT07403188
At-home Ultrasound Localized Therapy for Rheumatoid Arthritis Study [At-home ULTRA Study]
SecondWave Systems
NCT07163221
Probiotics in Adults With Rheumatoid Arthritis
Ancilia Biosciences
NCT07304505
Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis
Surf Therapeutics
NCT07293871
A Long-Term Follow-Up Observational Study to Evaluate Safety in Subjects Who Have Received a Gene-Modified Regulatory T Cell (Treg) Therapeutic
Sonoma Biotherapeutics
NCT07123038
The Effect of Guided Care With Vectra Compared to Treatment as Usual in Patients With Rheumatoid Arthritis
Sequenom
NCT03631225
A Trial of Academic Detailing to Promote Prescribing of Biosimilars
Brigham and Women's Hospital
NCT07221890
Food Trial to Evaluate the Kinetics of the Medical Foods SBD111 and SBD121 Persistence in Healthy Adults
Solarea Bio
NCT06614166
Phase IIIB Subcutaneous Abatacept Monotherapy Study
Bristol-Myers Squibb
NCT00547521
Comparison of Methotrexate (MTX) and the VIBEX™ MTX Device
Antares Pharma
NCT01618968
A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Efficacy of ABBV-3373 in Participants With Moderate to Severe Rheumatoid Arthritis (RA)
AbbVie
NCT03823391
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 5 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Rheumatoid Arthritis (RA) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Rheumatoid Arthritis (RA) trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Rheumatoid Arthritis (RA) page
18 registered trials, 12 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 12 Rheumatoid Arthritis (RA) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Brigham and Women's Hospital sponsors the most Rheumatoid Arthritis (RA) trials on record, review their full trial history before evaluating a specific study. See Brigham and Women's Hospital's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Rheumatoid Arthritis (RA) condition card totals 18 registered trials; most-linked intervention Placebo for adalimumab; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.