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NCT07293871 · ClinicalTrials.gov registry record · Phase 2

Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis

A Phase 2 study of Rheumatoid Arthritis (RA), sponsored by Surf Therapeutics.

Recruiting
Registry status
Phase 2
Development phase
40
Enrollment target
2
Study locations

NCT07293871 is a Phase 2 study of Rheumatoid Arthritis (RA) that is actively recruiting participants, run by Surf Therapeutics. The registered enrollment target is 40 participants, below the 266-participant average among 17 other Rheumatoid Arthritis (RA) trials with a reported enrollment target (85% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT07293871, a Phase 2 study of Rheumatoid Arthritis (RA), is actively recruiting participants, sponsored by Surf Therapeutics.

RECRUITING
Registry status
Phase 2
Development phase
40 participants
Enrollment target
2
Study locations

Study Summary

This two-stage, multicenter clinical trial is designed to evaluate the feasibility, safety, and preliminary efficacy of at-home ultrasound stimulation to activate immune-neuromodulation in patients with rheumatoid arthritis (RA) and at least moderate disease activity. The study will enroll up to 40 participants at up to 6 sites across 2 stages. The findings from this trial will directly inform the design and power calculations for a future pivotal trial by identifying an appropriate effect size and confirming protocol feasibility and safety for a daily home-use therapy.

Conditions Studied

Interventions

  • DEVICE Sham (No Treatment)
  • DEVICE Active treatment

Study Locations (2)

Texas

  • Precision Comprehensive Clinical Research Solutions - Colleyville
  • Precision Comprehensive Clinical Research Solutions - Irving

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2026-01
Est. Completion 2027-07
Phase Phase 2

Sponsor

Surf Therapeutics

2 total trials

What the Registry Record Tells You About NCT07293871

The ClinicalTrials.gov registry entry for NCT07293871 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 266-participant average among 17 other Rheumatoid Arthritis (RA) trials with a reported enrollment target (85% lower). The listed sponsor is Surf Therapeutics, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Rheumatoid Arthritis (RA) appearing as the primary indexed condition, and to 2 interventions - of which Sham (No Treatment) is the first listed.

NCT07293871 reports 2 study locations spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT07293871 about?

NCT07293871 is a clinical study titled "Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis". This two-stage, multicenter clinical trial is designed to evaluate the feasibility, safety, and preliminary efficacy of at-home ultrasound stimulation to activate immune-neuromodulation in patients with rheumatoid arthritis (RA) and at least moderate disease activity. The study will enroll up to 40 ...

What is the current status of trial NCT07293871?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2026-01. Estimated completion is 2027-07.

What conditions does trial NCT07293871 study?

This clinical trial studies the following conditions: Rheumatoid Arthritis (RA).

What interventions are being tested in trial NCT07293871?

The interventions under investigation include: Sham (No Treatment) (DEVICE), Active treatment (DEVICE).

Who is sponsoring clinical trial NCT07293871?

This trial is sponsored by Surf Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07293871 being conducted?

This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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