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NCT07293871 · ClinicalTrials.gov registry record · Phase 2
Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis
A Phase 2 study of Rheumatoid Arthritis (RA), sponsored by Surf Therapeutics.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 40
- Enrollment target
- 2
- Study locations
NCT07293871: Recruiting Phase 2 study of Rheumatoid Arthritis (RA), sponsored by Surf Therapeutics.
NCT07293871 is a Phase 2 study of Rheumatoid Arthritis (RA) that is actively recruiting participants, run by Surf Therapeutics. The registered enrollment target is 40 participants, below the 266-participant average among 17 other Rheumatoid Arthritis (RA) trials with a reported enrollment target (85% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07293871, a Phase 2 study of Rheumatoid Arthritis (RA), is actively recruiting participants, sponsored by Surf Therapeutics.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 40 participants
- Enrollment target
- 2
- Study locations
Study Summary
This two-stage, multicenter clinical trial is designed to evaluate the feasibility, safety, and preliminary efficacy of at-home ultrasound stimulation to activate immune-neuromodulation in patients with rheumatoid arthritis (RA) and at least moderate disease activity. The study will enroll up to 40 participants at up to 6 sites across 2 stages. The findings from this trial will directly inform the design and power calculations for a future pivotal trial by identifying an appropriate effect size and confirming protocol feasibility and safety for a daily home-use therapy.
Primary Outcome
All adverse events (AEs) regardless of treatment group that occur over the 12 week enrollment period will be coded and summarized by frequency, severity, and relatedness using the latest MedDRA version (v28.1).
Conditions Studied
Interventions
- DEVICE Sham (No Treatment)
- DEVICE Active treatment
Study Locations (2)
Texas
- Precision Comprehensive Clinical Research Solutions - Colleyville
- Precision Comprehensive Clinical Research Solutions - Irving
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2026-01 |
| Est. Completion | 2027-07 |
| Phase | Phase 2 |
What NCT07293871 shows while recruiting
NCT07293871 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 266-participant average among 17 other Rheumatoid Arthritis (RA) trials with a reported enrollment target (85% lower).
The record links to 1 condition, with Rheumatoid Arthritis (RA) appearing as the primary indexed condition, and to 2 interventions - of which Sham (No Treatment) is the first listed.
NCT07293871 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT07293871 about?
NCT07293871 is a clinical study titled "Ultrasound Neuroimmune Modulation in Adults With Rheumatoid Arthritis". This two-stage, multicenter clinical trial is designed to evaluate the feasibility, safety, and preliminary efficacy of at-home ultrasound stimulation to activate immune-neuromodulation in patients with rheumatoid arthritis (RA) and at least moderate disease activity. The study will enroll up to 40 ...
What is the current status of trial NCT07293871?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 40 participants. The study started on 2026-01. Estimated completion is 2027-07.
What conditions does trial NCT07293871 study?
This clinical trial studies the following conditions: Rheumatoid Arthritis (RA).
What interventions are being tested in trial NCT07293871?
The interventions under investigation include: Sham (No Treatment) (DEVICE), Active treatment (DEVICE).
Who is sponsoring clinical trial NCT07293871?
This trial is sponsored by Surf Therapeutics, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07293871 being conducted?
This trial has 2 study locations across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07293871's enrollment target sits among peer trials
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participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Rheumatoid Arthritis (RA) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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