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ClinicalTrials.gov 6 recruiting now official registry

Renal Cell Carcinoma (RCC) clinical trials

6 of 12 indexed Renal Cell Carcinoma (RCC) trials are currently recruiting.

12 US clinical trials · 6 currently recruiting

Renal Cell Carcinoma (RCC) is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 3 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Ciprian Catana, MD, PhD, running 1 of these trials.

The research picture

Renal Cell Carcinoma (RCC) has 12 registered US clinical trials, 6 of them open to new participants right now, about 50% of the total.

6
recruiting participants now
50%
of trials open to enrollment
3
in Phase 3–4 (later-stage)
1
top sponsor: Ciprian Catana, MD, PhD
Phase 13Phase 21Phase 33

Active & Recent Trials

12 total, page 1 of 1

RECRUITING Phase 1 1,314 participants

Study of Zanzalintinib in Combination With Immuno-Oncology Agents in Participants With Solid Tumors

Exelixis

NCT05176483

RECRUITING Phase 3 1,040 participants

Testing the Addition of the Anti-Cancer Drug Tivozanib to Immunotherapy (Pembrolizumab) After Surgery to Remove All Known Sites of Kidney Cancer

Alliance for Clinical Trials in Oncology

NCT06661720

RECRUITING Phase 1 358 participants

A Study to Evaluate the Safety and Therapeutic Activity of GI-102 As a Single Agent and in Combination with Conventional Anti-cancer Drugs, Pembrolizumab or Trastuzumab Deruxtecan(T-DXd) in Patients with Advanced Solid Tumors (KEYNOTE-G08)

GI Innovation

NCT05824975

RECRUITING NA 59 participants

ClAmpless, Sutureless PartIAl Nephrectomy for Renal Masses

University of Florida

NCT06722807

RECRUITING NA 25 participants

"Embolization Before Ablation of Renal Cell Carcinoma (EMBARC)"

University of Alabama at Birmingham

NCT05410509

RECRUITING NA 10 participants

Investigation of Lymph Node Biology in Kidney Cancer

Yale University

NCT07038733

ACTIVE NOT RECRUITING 135 participants

Multimodal Machine Learning Characterization of Solid Tumors

Ciprian Catana, MD, PhD

NCT04687969

ACTIVE NOT RECRUITING Phase 2 118 participants

A Trial of Belzutifan (PT2977, MK-6482) in Combination With Cabozantinib in Patients With Clear Cell Renal Cell Carcinoma (ccRCC) (MK-6482-003)

Peloton Therapeutics, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA)

NCT03634540

ACTIVE NOT RECRUITING 100 participants

A Pilot Study of Blood-based Biomarkers for Response to Immune Checkpoint Inhibitors

Ohio State University Comprehensive Cancer Center

NCT06630429

ACTIVE NOT RECRUITING Phase 1 33 participants

Ph I/II Trial of Systemic VSV-IFNβ-NIS in Combination With Checkpoint Inhibitor Therapy in Patients With Select Solid Tumors

Vyriad

NCT03647163

COMPLETED Phase 3 1,538 participants

A Study to Evaluate Pazopanib as an Adjuvant Treatment for Localized Renal Cell Carcinoma (RCC)

Novartis Pharmaceuticals

NCT01235962

COMPLETED Phase 3 129 participants

Pembrolizumab (MK-3475) Plus Epacadostat vs Standard of Care in mRCC (KEYNOTE-679/ECHO-302)

Incyte Corporation

NCT03260894

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 1
Phase 3 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Renal Cell Carcinoma (RCC) Trial Landscape

12 indexed Renal Cell Carcinoma (RCC) studies · 6 recruiting (50%).

Phase mix: 3 late (III/IV) vs 4 early (I/II).

Top sponsor: Ciprian Catana, MD, PhD (1 trial), 9 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Renal Cell Carcinoma (RCC)?

PlainTrial tracks 12 US clinical trials for Renal Cell Carcinoma (RCC), of which 6 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Renal Cell Carcinoma (RCC)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.