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ClinicalTrials.gov 13 recruiting now official registry

Relapsed Non-Hodgkin Lymphoma clinical trials

13 of 17 indexed Relapsed Non-Hodgkin Lymphoma trials are currently recruiting.

17 US clinical trials · 13 currently recruiting

Relapsed Non-Hodgkin Lymphoma is the subject of 17 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 16 in Phase 1-2 (earlier-stage). The most active sponsor is Lyell Immunopharma, running 2 of these trials.

The research picture

Relapsed Non-Hodgkin Lymphoma has 17 registered US clinical trials, 13 of them open to new participants right now, about 76% of the total.

13
recruiting participants now
76%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
2
top sponsor: Lyell Immunopharma
Phase 112Phase 24Phase 31

Active & Recent Trials

17 total, page 1 of 1

RECRUITING Phase 3 400 participants

A Study to Investigate Ronde-cel Versus Investigator's Choice CD19 CAR T-Cell Therapy

Lyell Immunopharma

NCT07188558

RECRUITING Phase 1 270 participants

Study of LYL314 in Aggressive Large B-Cell Lymphoma

Lyell Immunopharma

NCT05826535

RECRUITING Phase 1 128 participants

IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

Indapta Therapeutics

NCT06119685

RECRUITING Phase 1 100 participants

Phase 1/2: CD45RA Depleted Stem Cell Addback to Prevent Viral or Fungal Infections Post TCRab/CD19 Depleted HSCT

Children's Hospital of Philadelphia

NCT06839456

RECRUITING Phase 1 72 participants

CRISPR-Edited Allogeneic Anti-CD19 CAR-T Cell Therapy for Relapsed/Refractory B Cell Non-Hodgkin Lymphoma (ANTLER)

Caribou Biosciences

NCT04637763

RECRUITING Phase 2 28 participants

Emapalumab Prevention of CAR-T Cell Associated Toxicities

Marcela V. Maus, M.D.,Ph.D.

NCT06550141

RECRUITING Phase 2 27 participants

Single-Arm Comprehensive Ablative Bridging Irradiation I Prior to CD19 CAR-T In High-Risk R/R LBCL

H. Lee Moffitt Cancer Center and Research Institute

NCT06104592

RECRUITING Phase 1 24 participants

Study of SIRPant-M in Participants With Relapsed or Refractory Non-Hodgkin's Lymphoma

SIRPant Immunotherapeutics

NCT05967416

RECRUITING Phase 2 24 participants

A Phase II Study of the Combination of Pembrolizumab and ATRA Combination Treatment of Relapsed HL and B-NHL

Rita Assi

NCT06484920

RECRUITING Phase 1 24 participants

CD79b-19 CAR T Cells in Non-Hodgkin Lymphoma

Marcela V. Maus, M.D.,Ph.D.

NCT06026319

RECRUITING Phase 2 22 participants

CAR-T Cell Therapy, Mosunetuzumab and Polatuzumab for Treatment of Refractory/Relapsed Aggressive Non-Hodgkin's Lymphoma (NHL).

Lazaros Lekakis

NCT05260957

RECRUITING Phase 1 21 participants

T-Cell Therapy (EB103) in Adults With Relapsed/Refractory B-Cell Non-Hodgkin's Lymphoma (NHL)

Estrella Biopharma

NCT06343311

RECRUITING Phase 1 18 participants

SynKIR-310 for Relapsed/Refractory B-NHL

Verismo Therapeutics

NCT06544265

ACTIVE NOT RECRUITING Phase 1 112 participants

A Study of BGB-21447, a Bcl-2 Inhibitor, in Mature B-Cell Malignancies

BeOne Medicines

NCT05828589

ACTIVE NOT RECRUITING Phase 1 33 participants

Low Dose Radiation as Bridging Therapy in Relapsed B-Cell Non-Hodgkin Lymphoma

University of Nebraska

NCT05621096

ACTIVE NOT RECRUITING Phase 1 23 participants

Loncastuximab Tesirine and Venetoclax for Relapsed/ Refractory Non-Hodgkin Lymphoma

Paolo Caimi, MD

NCT05053659

ACTIVE NOT RECRUITING Phase 1 13 participants

CD19.CAR Allogeneic NKT for Patients With Relapsed or Refractory B-Cell Malignancies (ANCHOR)

Baylor College of Medicine

NCT03774654

Phase Distribution

PhaseTrial count
Phase 1 12
Phase 2 4
Phase 3 1

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Relapsed Non-Hodgkin Lymphoma Trial Landscape

17 indexed Relapsed Non-Hodgkin Lymphoma studies · 13 recruiting (76%).

Phase mix: 1 late (III/IV) vs 16 early (I/II).

Top sponsor: Lyell Immunopharma (2 trials), 9 others listed. 17 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Relapsed Non-Hodgkin Lymphoma?

PlainTrial tracks 17 US clinical trials for Relapsed Non-Hodgkin Lymphoma, of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Relapsed Non-Hodgkin Lymphoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.