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NCT06484920 · ClinicalTrials.gov registry record · Phase 2

A Phase II Study of the Combination of Pembrolizumab and ATRA Combination Treatment of Relapsed HL and B-NHL

A Phase 2 study of B-cell Lymphoma and Refractory Non-Hodgkin Lymphoma, sponsored by Rita Assi.

Recruiting
Registry status
Phase 2
Development phase
24
Enrollment target
2
Study locations

NCT06484920 is a Phase 2 study of B-cell Lymphoma and Refractory Non-Hodgkin Lymphoma that is actively recruiting participants, run by Rita Assi. The registered enrollment target is 24 participants, below the 90-participant average among 38 other B-cell Lymphoma trials with a reported enrollment target (73% lower). The trial reports 2 study locations across 1 state.

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The verdict

NCT06484920, a Phase 2 study of B-cell Lymphoma and Refractory Non-Hodgkin Lymphoma, is actively recruiting participants, sponsored by Rita Assi.

RECRUITING
Registry status
Phase 2
Development phase
24 participants
Enrollment target
2
Study locations

Study Summary

This is a Phase II single-center open label trial of the combination of ATRA and pembrolizumab treatment in patients with histologically proven, relapsed or refractory Hodgkin Lymphoma or B-Non-Hodgkin-lymphoma.

Interventions

  • DRUG Pembrolizumab
  • DRUG ATRA

Study Locations (2)

Indiana

  • Indiana University Health Melvin and Bren Simon Comprehensive Cancer Center - Indianapolis
  • Sidney and Lois Eskenazi Hospital - Indianapolis

Trial Details

FieldValue
Enrollment Target 24 participants
Start Date 2024-11-18
Est. Completion 2029-09
Phase Phase 2

Sponsor

Rita Assi

1 total trials

What the Registry Record Tells You About NCT06484920

The ClinicalTrials.gov registry entry for NCT06484920 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 90-participant average among 38 other B-cell Lymphoma trials with a reported enrollment target (73% lower). The listed sponsor is Rita Assi, which has 1 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with B-cell Lymphoma appearing as the primary indexed condition, and to 2 interventions - of which Pembrolizumab is the first listed.

NCT06484920 reports 2 study locations spanning 1 distinct geographic area - top geographies include Indiana.

Frequently Asked Questions

What is clinical trial NCT06484920 about?

NCT06484920 is a clinical study titled "A Phase II Study of the Combination of Pembrolizumab and ATRA Combination Treatment of Relapsed HL and B-NHL". This is a Phase II single-center open label trial of the combination of ATRA and pembrolizumab treatment in patients with histologically proven, relapsed or refractory Hodgkin Lymphoma or B-Non-Hodgkin-lymphoma.

What is the current status of trial NCT06484920?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 24 participants. The study started on 2024-11-18. Estimated completion is 2029-09.

What conditions does trial NCT06484920 study?

This clinical trial studies the following conditions: B-cell Lymphoma, Refractory Non-Hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma, Refractory Hodgkin Lymphoma, Relapsed Hodgkin Lymphoma.

What interventions are being tested in trial NCT06484920?

The interventions under investigation include: Pembrolizumab (DRUG), ATRA (DRUG).

Who is sponsoring clinical trial NCT06484920?

This trial is sponsored by Rita Assi, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06484920 being conducted?

This trial has 2 study locations across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.