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RECRUITING Phase 1

IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers

NCT06119685 · View on ClinicalTrials.gov ↗

Study Summary

This is an open label, Phase 1/2, first-in-human, multiple ascending dose, and dose-expansion study of IDP-023 administered as a single agent and in combination with or without interleukin-2 (IL-2), and with or without isatuximab, daratumumab or rituximab to evaluate the safety, tolerability and preliminary antitumor activity in patients with advanced hematologic cancers.

Interventions

  • DRUG Cyclophosphamide
  • DRUG Rituximab
  • DRUG Daratumumab
  • DRUG Interleukin-2
  • DRUG IDP-023

Study Locations (12)

California

  • Valkyrie Clinical Trials — Los Angeles

Florida

  • Florida Cancer Specialists and Research Institute - Lake Mary Cancer Center — Lake Mary

Georgia

  • Emory University Hospital — Atlanta

Minnesota

  • University of Minnesota — Minneapolis

New York

  • NYP/Weill Cornell Medical Center — New York

North Carolina

  • Atrium Health Wake Forest Baptist — Winston-Salem

Ohio

  • University Hospitals Cleveland — Cleveland

Oregon

  • Providence Cancer Institute Franz Clinic — Portland

Trial Details

FieldValue
Enrollment Target 128 participants
Start Date 2023-10-25
Est. Completion 2029-12-31
Phase Phase 1

Sponsor

Indapta Therapeutics

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06119685

The ClinicalTrials.gov registry entry for NCT06119685 describes a study currently listed as recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 128 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Indapta Therapeutics, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 7 conditions, with Multiple Myeloma appearing as the primary indexed condition, and to 5 interventions — of which Cyclophosphamide is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06119685 reports 12 study locations spanning 12 distinct geographic areas — top geographies include California, Florida, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06119685 about?

NCT06119685 is a clinical study titled "IDP-023 as a Single Agent and in Combination With Antibody Therapies in Patients With Advanced Hematologic Cancers". This is an open label, Phase 1/2, first-in-human, multiple ascending dose, and dose-expansion study of IDP-023 administered as a single agent and in combination with or without interleukin-2 (IL-2), and with or without isatuximab, daratumumab or rituximab to evaluate the safety, tolerability and pre...

What is the current status of trial NCT06119685?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 128 participants. The study started on 2023-10-25. Estimated completion is 2029-12-31.

What conditions does trial NCT06119685 study?

This clinical trial studies the following conditions: Multiple Myeloma, Refractory Multiple Myeloma, Refractory Non-Hodgkin Lymphoma, Relapsed Non-Hodgkin Lymphoma, Blood Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06119685?

The interventions under investigation include: Cyclophosphamide (DRUG), Rituximab (DRUG), Daratumumab (DRUG), Interleukin-2 (DRUG), IDP-023 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06119685?

This trial is sponsored by Indapta Therapeutics, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06119685 being conducted?

This trial has 12 study locations across California, Florida, Georgia, Minnesota, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial