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NCT03579316 · ClinicalTrials.gov registry record · Phase 2

Adavosertib With or Without Olaparib in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

A Phase 2 study of Recurrent Ovarian Carcinoma and Recurrent Fallopian Tube Carcinoma, sponsored by M.D. Anderson Cancer Center.

Active
Registry status
Phase 2
Development phase
96
Enrollment target
2
Study locations

NCT03579316 is a Phase 2 study of Recurrent Ovarian Carcinoma and Recurrent Fallopian Tube Carcinoma that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 96 participants, below the 122-participant average among 39 other Recurrent Ovarian Carcinoma trials with a reported enrollment target (21% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT03579316, a Phase 2 study of Recurrent Ovarian Carcinoma and Recurrent Fallopian Tube Carcinoma, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
96 participants
Enrollment target
2
Study locations

Study Summary

This phase II trial studies how well adavosertib with or without olaparib work in treating patients with ovarian, primary peritoneal, or fallopian tube cancer that has come back (recurrent). Adavosertib and olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell growth.

Interventions

  • DRUG Olaparib
  • DRUG Ceralasertib
  • DRUG Adavosertib

Study Locations (2)

Massachusetts

  • Dana-Farber Cancer Institute - Boston

Texas

  • M D Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 96 participants
Start Date 2018-12-07
Est. Completion 2026-12-31
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT03579316

The ClinicalTrials.gov registry entry for NCT03579316 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 96 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 122-participant average among 39 other Recurrent Ovarian Carcinoma trials with a reported enrollment target (21% lower). The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Recurrent Ovarian Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Olaparib is the first listed.

NCT03579316 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Massachusetts, Texas.

Frequently Asked Questions

What is clinical trial NCT03579316 about?

NCT03579316 is a clinical study titled "Adavosertib With or Without Olaparib in Treating Patients With Recurrent Ovarian, Primary Peritoneal, or Fallopian Tube Cancer". This phase II trial studies how well adavosertib with or without olaparib work in treating patients with ovarian, primary peritoneal, or fallopian tube cancer that has come back (recurrent). Adavosertib and olaparib may stop the growth of tumor cells by blocking some of the enzymes needed for cell g...

What is the current status of trial NCT03579316?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 96 participants. The study started on 2018-12-07. Estimated completion is 2026-12-31.

What conditions does trial NCT03579316 study?

This clinical trial studies the following conditions: Recurrent Ovarian Carcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Primary Peritoneal Carcinoma.

What interventions are being tested in trial NCT03579316?

The interventions under investigation include: Olaparib (DRUG), Ceralasertib (DRUG), Adavosertib (DRUG).

Who is sponsoring clinical trial NCT03579316?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03579316 being conducted?

This trial has 2 study locations across Massachusetts, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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