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NCT01305213 · ClinicalTrials.gov registry record · Phase 2
Bevacizumab With or Without Fosbretabulin Tromethamine in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer
A Phase 2 study of Recurrent Ovarian Carcinoma and Recurrent Fallopian Tube Carcinoma, sponsored by National Cancer Institute (NCI).
- Completed
- Registry status
- Phase 2
- Development phase
- 107
- Enrollment target
- 20
- Study locations
NCT01305213 is a Phase 2 study of Recurrent Ovarian Carcinoma and Recurrent Fallopian Tube Carcinoma that has completed, run by National Cancer Institute (NCI). The registered enrollment target is 107 participants, below the 121-participant average among 39 other Recurrent Ovarian Carcinoma trials with a reported enrollment target (12% lower). The trial reports 20 study locations across 10 states.
The verdict
NCT01305213, a Phase 2 study of Recurrent Ovarian Carcinoma and Recurrent Fallopian Tube Carcinoma, has completed, sponsored by National Cancer Institute (NCI).
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 107 participants
- Enrollment target
- 20
- Study locations
Study Summary
This randomized phase II trial studies how well bevacizumab with or without fosbretabulin tromethamine works in treating patients with ovarian epithelial, fallopian tube, or peritoneal cavity cancer that has come back or is persistent. Monoclonal antibodies, such as bevacizumab, find tumor cells and help kill them. Bevacizumab and fosbretabulin tromethamine may stop the growth of ovarian cancer by blocking blood flow to the tumor. It is not yet known whether bevacizumab is more effective with or without fosbretabulin tromethamine in treating ovarian epithelial, fallopian tube, and peritoneal cavity cancer.
Conditions Studied
Interventions
- OTHER Laboratory Biomarker Analysis
- BIOLOGICAL Bevacizumab
- DRUG Fosbretabulin Tromethamine
Study Locations (20)
California
- Providence Saint Joseph Medical Center/Disney Family Cancer Center - Burbank
- John Muir Medical Center-Concord Campus - Concord
- UC San Diego Moores Cancer Center - La Jolla
- Cedars Sinai Medical Center - Los Angeles
- Sutter Medical Center Sacramento - Sacramento
Colorado
- Penrose-Saint Francis Healthcare - Colorado Springs
- Presbyterian - Saint Lukes Medical Center - Health One - Denver
- SCL Health Lutheran Medical Center - Wheat Ridge
Delaware
- Beebe Medical Center - Lewes
- Christiana Care Health System-Christiana Hospital - Newark
Georgia
- Northeast Georgia Medical Center-Gainesville - Gainesville
- Memorial Health University Medical Center - Savannah
Illinois
- University of Chicago Comprehensive Cancer Center - Chicago
- Sudarshan K Sharma MD Limited-Gynecologic Oncology - Hinsdale
Indiana
- Indiana University/Melvin and Bren Simon Cancer Center - Indianapolis
- Saint Vincent Hospital and Health Care Center - Indianapolis
Arizona
- Saint Joseph's Hospital and Medical Center - Phoenix
Connecticut
- Hartford Hospital - Hartford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 107 participants |
| Start Date | 2011-03-21 |
| Est. Completion | 2016-11-03 |
| Phase | Phase 2 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01305213
The ClinicalTrials.gov registry entry for NCT01305213 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 107 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 121-participant average among 39 other Recurrent Ovarian Carcinoma trials with a reported enrollment target (12% lower). The listed sponsor is National Cancer Institute (NCI), which has 3,257 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Recurrent Ovarian Carcinoma appearing as the primary indexed condition, and to 3 interventions - of which Laboratory Biomarker Analysis is the first listed.
NCT01305213 reports 20 study locations spanning 10 distinct geographic areas - top geographies include California, Colorado, Delaware.
Frequently Asked Questions
What is clinical trial NCT01305213 about?
NCT01305213 is a clinical study titled "Bevacizumab With or Without Fosbretabulin Tromethamine in Treating Patients With Recurrent or Persistent Ovarian Epithelial, Fallopian Tube, or Peritoneal Cavity Cancer". This randomized phase II trial studies how well bevacizumab with or without fosbretabulin tromethamine works in treating patients with ovarian epithelial, fallopian tube, or peritoneal cavity cancer that has come back or is persistent. Monoclonal antibodies, such as bevacizumab, find tumor cells and...
What is the current status of trial NCT01305213?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 107 participants. The study started on 2011-03-21. Estimated completion is 2016-11-03.
What conditions does trial NCT01305213 study?
This clinical trial studies the following conditions: Recurrent Ovarian Carcinoma, Recurrent Fallopian Tube Carcinoma, Recurrent Primary Peritoneal Carcinoma.
What interventions are being tested in trial NCT01305213?
The interventions under investigation include: Laboratory Biomarker Analysis (OTHER), Bevacizumab (BIOLOGICAL), Fosbretabulin Tromethamine (DRUG).
Who is sponsoring clinical trial NCT01305213?
This trial is sponsored by National Cancer Institute (NCI), which has 3,257 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01305213 being conducted?
This trial has 20 study locations across Arizona, California, Colorado, Connecticut, Delaware. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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