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ACTIVE NOT RECRUITING Phase 3

Cancer Stem Cell Assay Directed Chemotherapy in Recurrent Platinum Resistant Ovarian Cancer

NCT03949283 · View on ClinicalTrials.gov ↗

Study Summary

The purpose of this clinical study is to confirm the utility of chemosensitivity (ChemoID) tumor testing on cancer stem cells as a predictor of clinical response in recurrent platinum resistant epithelial ovarian cancer (EOC), fallopian tube, or primary peritoneal cancer. Population studied will be female participants experiencing a recurrent platinum-resistant ovarian cancer (no mucinous, low grade serous, or pure sarcoma types), with ≤ 5 prior treatments, and a performance status 0-1.

Interventions

  • DRUG Standard Chemotherapy
  • DIAGNOSTIC_TEST ChemoID Assay

Study Locations (8)

West Virginia

  • Charleston Area Medical Center (CAMC) — Charleston
  • Edwards Comprehensive Cancer Center - Cabell Huntington Hospital — Huntington

California

  • Kaiser Permanente — Los Angeles

Florida

  • Miami Cancer Institute/Baptist Health South Florida — Miami

Louisiana

  • LSU Health Sciences Center — New Orleans

Ohio

  • University of Cincinnati Cancer Institute — Cincinnati

Oklahoma

  • University of Oklahoma Health Sciences Center — Oklahoma City

Pennsylvania

  • West Penn Hospital, Allegheny Health Network — Pittsburgh

Trial Details

FieldValue
Enrollment Target 150 participants
Start Date 2019-07-26
Est. Completion 2024-12-30
Phase Phase 3

Sponsor

Cordgenics

1 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT03949283

The ClinicalTrials.gov registry entry for NCT03949283 describes a study currently listed as active not recruiting. It is categorized as Phase 3, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 150 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Cordgenics, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 2 conditions, with Recurrent Ovarian Carcinoma appearing as the primary indexed condition, and to 2 interventions — of which Standard Chemotherapy is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT03949283 reports 8 study locations spanning 7 distinct geographic areas — top geographies include West Virginia, California, Florida. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT03949283 about?

NCT03949283 is a clinical study titled "Cancer Stem Cell Assay Directed Chemotherapy in Recurrent Platinum Resistant Ovarian Cancer". The purpose of this clinical study is to confirm the utility of chemosensitivity (ChemoID) tumor testing on cancer stem cells as a predictor of clinical response in recurrent platinum resistant epithelial ovarian cancer (EOC), fallopian tube, or primary peritoneal cancer. Population studied will be...

What is the current status of trial NCT03949283?

This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 150 participants. The study started on 2019-07-26. Estimated completion is 2024-12-30.

What conditions does trial NCT03949283 study?

This clinical trial studies the following conditions: Recurrent Ovarian Carcinoma, Platinum-resistant Ovarian Cancer. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT03949283?

The interventions under investigation include: Standard Chemotherapy (DRUG), ChemoID Assay (DIAGNOSTIC_TEST). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT03949283?

This trial is sponsored by Cordgenics, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT03949283 being conducted?

This trial has 8 study locations across California, Florida, Louisiana, Ohio, Oklahoma. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial