Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Plexiform Neurofibroma: early-phase trial registry
3 of 8 indexed Plexiform Neurofibroma trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 3 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Plexiform Neurofibroma: 8 US clinical trials tracked, 3 recruiting.
Plexiform Neurofibroma is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Shanghai Fosun Pharmaceutical Industrial Development Co., running 1 of these trials.
Enrollment posture brief
Registry condition plexiform-neurofibroma
OPEN 3 | RECR 38% | LATE 0 | EARLY 4 | RANK #2176 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Acute-graft-versus-host Disease (38% recruiting · 8 trials)
Plexiform Neurofibroma lists 3 open slots (38% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Plexiform Neurofibroma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Plexiform Neurofibroma is recruiting below its size-band peers.
3 of 8 indexed trials (37.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Plexiform Neurofibroma trials is spread across many organizations.
Shanghai Fosun Pharmaceutical Industrial Development Co. accounts for 1 of 8 trials (12.5%). 8 distinct sponsors appear on at least one study for this condition label.
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Typical Plexiform Neurofibroma enrolment sits around 160 participants.
Median target enrolment is 160 among the 8 trials that report a genuine target (sentinel values excluded). 3 of those (37.5%) plan for fewer than 100 participants.
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Plexiform Neurofibroma splits between interventional and observational designs.
5 interventional and 3 observational studies make up this index (62.5% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Neurofibromatosis Type 1 Tumor Early Detection Study
David Miller
NCT06515860
Selumetinib for the Prevention of Plexiform Neurofibroma Growth in NF Type 1
University of Alabama at Birmingham
NCT06188741
A Study of Avutometinib for People With Solid Tumor Cancers
Memorial Sloan Kettering Cancer Center
NCT06104488
Natural History Study of Patients With Neurofibromatosis Type I
National Cancer Institute (NCI)
NCT00924196
Study to Evaluate the Safety, Tolerability, PK Characteristics and Anti-tumor Activity of FCN-159 in Adult and Pediatric Participants With Neurofibromatosis Type 1
Shanghai Fosun Pharmaceutical Industrial Development Co.
NCT04954001
MEK Inhibitor Mirdametinib (PD-0325901) in Patients With Neurofibromatosis Type 1 Associated Plexiform Neurofibromas
SpringWorks Therapeutics
NCT03962543
Whole Body MRI to Identify Atypical Neurofibromas in Patients With NF1
Children's National Research Institute
NCT03820778
PET/MRI in CNS and Extra-CNS Tumors of Patients With Neurofibromatosis-1 (NF1)
UNC Lineberger Comprehensive Cancer Center
NCT01800032
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Plexiform Neurofibroma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Plexiform Neurofibroma trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Plexiform Neurofibroma page
8 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Plexiform Neurofibroma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Shanghai Fosun Pharmaceutical Industrial Development Co. sponsors the most Plexiform Neurofibroma trials on record, review their full trial history before evaluating a specific study. See Shanghai Fosun Pharmaceutical Industrial Development Co.'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Plexiform Neurofibroma condition card totals 8 registered trials; most-linked intervention Whole Body MRI; top US site state District of Columbia. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.