Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04800692 · ClinicalTrials.gov registry record · Phase 1
The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication
A Phase 1 study of Peripheral Artery Disease and Peripheral Vascular Diseases, sponsored by Louis Messina.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT04800692 is a Phase 1 study of Peripheral Artery Disease and Peripheral Vascular Diseases that is actively recruiting participants, run by Louis Messina. The registered enrollment target is 10 participants, below the 127-participant average among 50 other Peripheral Artery Disease trials with a reported enrollment target (92% lower). The trial reports 1 study location across 1 state.
The verdict
NCT04800692, a Phase 1 study of Peripheral Artery Disease and Peripheral Vascular Diseases, is actively recruiting participants, sponsored by Louis Messina.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
This study will focus on people with claudication from peripheral arterial disease. The investigators are researching whether a multicomponent therapeutic can increase the production of Nitric Oxide in the blood and whether that leads to an improvement in pain free walking distance and overall physical activity.
Conditions Studied
Interventions
- DRUG Tetrahydrobiopterin 10 mg/kg
- DRUG Tetrahydrobiopterin 20 mg/kg
- DRUG L-Ascorbate
- DRUG L-Arginine
Study Locations (1)
Massachusetts
- UMASS Memorial Healthcare - University Campus - Worcester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2021-06-15 |
| Est. Completion | 2027-12 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04800692
The ClinicalTrials.gov registry entry for NCT04800692 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 127-participant average among 50 other Peripheral Artery Disease trials with a reported enrollment target (92% lower). The listed sponsor is Louis Messina, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 3 conditions, with Peripheral Artery Disease appearing as the primary indexed condition, and to 4 interventions - of which Tetrahydrobiopterin 10 mg/kg is the first listed.
NCT04800692 reports 1 study location spanning 1 distinct geographic area - top geographies include Massachusetts.
Frequently Asked Questions
What is clinical trial NCT04800692 about?
NCT04800692 is a clinical study titled "The Effects of ATLAS Therapy on Nitric Oxide Bioavailability in Patients With Intermittent Claudication". This study will focus on people with claudication from peripheral arterial disease. The investigators are researching whether a multicomponent therapeutic can increase the production of Nitric Oxide in the blood and whether that leads to an improvement in pain free walking distance and overall physi...
What is the current status of trial NCT04800692?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 10 participants. The study started on 2021-06-15. Estimated completion is 2027-12.
What conditions does trial NCT04800692 study?
This clinical trial studies the following conditions: Peripheral Artery Disease, Peripheral Vascular Diseases, Claudication, Intermittent.
What interventions are being tested in trial NCT04800692?
The interventions under investigation include: Tetrahydrobiopterin 10 mg/kg (DRUG), Tetrahydrobiopterin 20 mg/kg (DRUG), L-Ascorbate (DRUG), L-Arginine (DRUG).
Who is sponsoring clinical trial NCT04800692?
This trial is sponsored by Louis Messina, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04800692 being conducted?
This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Peripheral Artery Disease
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
-
Use of Autologous Concentrated Bone Marrow Aspirate in Preventing Wound Complications in Below Knee Amputation (BKA)
COMPLETED · Phase 1
-
NAD Supplementation and Vascular Health in PAD
COMPLETED · Phase 1
-
Pilot Study of PRT-201 Following Angioplasty in Patients With Peripheral Artery Disease (PAD)
COMPLETED · Phase 1
-
Response to Exercise and Nitric Oxide in PAD
RECRUITING · Phase 2
-
Improving Mobility After Revascularization in Peripheral Artery Disease
RECRUITING · Phase 3
-
The Effects of a Novel, Non-ischemic and Pain-free Exercise Intervention in Peripheral Artery Disease
RECRUITING · NA
Explore more on PlainTrial
Peripheral Artery Disease
All registered trials for this condition
Peripheral Vascular Diseases
All registered trials for this condition
Massachusetts
All trials with a study site in Massachusetts
Recruiting now
Find trials open to new participants near you
Rankings
Top sponsors, conditions, and phases
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.