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ClinicalTrials.gov 13 recruiting now official registry

Parkinsons Disease (PD) clinical trials

13 of 20 indexed Parkinsons Disease (PD) trials are currently recruiting.

20 US clinical trials · 13 currently recruiting

Parkinsons Disease (PD) is the subject of 20 registered US clinical trials on ClinicalTrials.gov, 13 of them currently open to new participants. 5 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is AbbVie, running 5 of these trials.

The research picture

Parkinsons Disease (PD) has 20 registered US clinical trials, 13 of them open to new participants right now, about 65% of the total.

13
recruiting participants now
65%
of trials open to enrollment
5
in Phase 3–4 (later-stage)
5
top sponsor: AbbVie
Phase 15Phase 23Phase 35

Active & Recent Trials

20 total, page 1 of 1

RECRUITING Phase 2 500 participants

A Study of Buntanetap in Participants With PD

Annovis Bio

NCT07284784

RECRUITING 450 participants

Real-World Study of ABBV-951 Subcutaneous Infusion to Assess Change in Disease Activity in Adult Participants With Parkinson's Disease

AbbVie

NCT06107426

RECRUITING 120 participants

Neuroimaging of Parkinson's

Washington University School of Medicine

NCT07024875

RECRUITING Phase 3 102 participants

A Study to Investigate the Efficacy and Safety of Bemdaneprocel in Adults Who Have Parkinson's Disease

BlueRock Therapeutics

NCT06944522

RECRUITING NA 80 participants

Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations

University of Colorado, Denver

NCT07424365

RECRUITING NA 80 participants

Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients

Boston University Charles River Campus

NCT07455760

RECRUITING NA 75 participants

Effects of Vagal Nerve Stimulation on Leg Muscle Activity and Posture in Parkinson's Disease

University of Minnesota

NCT07226284

RECRUITING NA 64 participants

Transcranial Direct Current Stimulation for Motor Function and Fatigue in PD

Sanford Health

NCT06883266

RECRUITING Phase 2 62 participants

A Phase 2a Multicenter Clinical Trial of TB006 in Participants With Parkinson's Disease

TrueBinding

NCT06773962

RECRUITING Phase 2 60 participants

A Study of NE3107 in Early Parkinson's

BioVie

NCT06757010

RECRUITING NA 30 participants

Electrophysiology-based DBS Programming for PD

University of Florida

NCT07348705

RECRUITING Early Phase 1 22 participants

Open-label Study to Evaluate Brain α-Synuclein Deposition Using PET and [18F]MK-0947 in Parkinson's Disease

Invicro

NCT07348250

RECRUITING Phase 1 12 participants

Enrichment of Glutathione Using Gamma-glutamylcysteine Supplementation in Parkinson's Disease Patients.

Pravat Mandal

NCT07064005

ACTIVE NOT RECRUITING Phase 3 130 participants

Extension Study To Evaluate Safety And Tolerability Of 24-Hour Daily Exposure Of Continuous Subcutaneous Infusion of ABBV-951 In Adult Participants With Parkinson's Disease

AbbVie

NCT04379050

ACTIVE NOT RECRUITING Phase 3 118 participants

Study To Assess Adverse Events and Change in Disease Activity Of 24-hour Continuous Subcutaneous Infusion Of ABBV-951 In Adult Participants With Advanced Parkinson's Disease

AbbVie

NCT04750226

COMPLETED Phase 3 223 participants

Open-Label Safety Study of ADS-5102 in PD Patients With LID

Adamas Pharmaceuticals

NCT02202551

COMPLETED Phase 3 77 participants

Efficacy and Safety Study of ADS-5102 in PD Patients With Levodopa-Induced Dyskinesia

Adamas Pharmaceuticals

NCT02274766

COMPLETED Phase 1 29 participants

A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous Infusions of ABBV-951 in Subjects With Parkinson's Disease

AbbVie

NCT03033498

COMPLETED Phase 1 20 participants

A Study in Subjects With Parkinson's Disease to Evaluate the Safety and Tolerability of Titration and Continuous Subcutaneous Infusion of ABBV-951 in an Outpatient Environment

AbbVie

NCT03374917

COMPLETED Phase 1 16 participants

Evaluation of [18F]MNI-777 PET as a Marker of Tau Pathology in Subjects With Tauopathies Compared to Healthy Subjects

Molecular NeuroImaging

NCT02103894

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 3
Phase 3 5

Top Sponsors

AbbVie 5 trials
Annovis Bio 1 trials
Pravat Mandal 1 trials
BioVie 1 trials
TrueBinding 1 trials
Invicro 1 trials
Sanford Health 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Parkinsons Disease (PD) Trial Landscape

20 indexed Parkinsons Disease (PD) studies · 13 recruiting (65%).

Phase mix: 5 late (III/IV) vs 8 early (I/II).

Top sponsor: AbbVie (5 trials), 9 others listed. 20 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Parkinsons Disease (PD)?

PlainTrial tracks 20 US clinical trials for Parkinsons Disease (PD), of which 13 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Parkinsons Disease (PD)?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.