Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07226284 · ClinicalTrials.gov registry record · NA
Effects of Vagal Nerve Stimulation on Leg Muscle Activity and Posture in Parkinson's Disease
A NA study of Parkinsons Disease (PD) and PARKINSON DISEASE (Disorder), sponsored by University of Minnesota.
- Recruiting
- Registry status
- NA
- Development phase
- 75
- Enrollment target
- 1
- Study location
NCT07226284: Recruiting NA study of Parkinsons Disease (PD) and PARKINSON DISEASE (Disorder), sponsored by University of Minnesota.
NCT07226284 is a NA study of Parkinsons Disease (PD) and PARKINSON DISEASE (Disorder) that is actively recruiting participants, run by University of Minnesota. The registered enrollment target is 75 participants, below the 116-participant average among 19 other Parkinsons Disease (PD) trials with a reported enrollment target (35% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07226284, a NA study of Parkinsons Disease (PD) and PARKINSON DISEASE (Disorder), is actively recruiting participants, sponsored by University of Minnesota.
- RECRUITING
- Registry status
- NA
- Development phase
- 75 participants
- Enrollment target
- 1
- Study location
Study Summary
This study is designed to better understand the mechanisms contributing to impaired activation of leg muscles in people with Parkinson's disease (PD) and to test if stimulation of a nerve at the neck can improve muscle activation, walking and balance.
Primary Outcome
Difference between baseline and post-VNS delta-F measure
Conditions Studied
Interventions
- OTHER No intervention
- DEVICE Vagal nerve stimulation
Study Locations (1)
Minnesota
- Movement Disorders Laboratory - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 75 participants |
| Start Date | 2026-02-10 |
| Est. Completion | 2029-01 |
| Phase | NA |
What NCT07226284 shows while recruiting
NCT07226284 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 116-participant average among 19 other Parkinsons Disease (PD) trials with a reported enrollment target (35% lower).
The record links to 2 conditions, with Parkinsons Disease (PD) appearing as the primary indexed condition, and to 2 interventions - of which No intervention is the first listed.
NCT07226284 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT07226284 about?
NCT07226284 is a clinical study titled "Effects of Vagal Nerve Stimulation on Leg Muscle Activity and Posture in Parkinson's Disease". This study is designed to better understand the mechanisms contributing to impaired activation of leg muscles in people with Parkinson's disease (PD) and to test if stimulation of a nerve at the neck can improve muscle activation, walking and balance.
What is the current status of trial NCT07226284?
This trial is currently recruiting. It is a NA study. The enrollment target is 75 participants. The study started on 2026-02-10. Estimated completion is 2029-01.
What conditions does trial NCT07226284 study?
This clinical trial studies the following conditions: Parkinsons Disease (PD), PARKINSON DISEASE (Disorder).
What interventions are being tested in trial NCT07226284?
The interventions under investigation include: No intervention (OTHER), Vagal nerve stimulation (DEVICE).
Who is sponsoring clinical trial NCT07226284?
This trial is sponsored by University of Minnesota, which has 966 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07226284 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Parkinsons Disease (PD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07226284's enrollment target sits among peer trials
75 11th of 19 higher than 9 of 19 other Parkinsons Disease (PD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinsons Disease (PD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Transcranial Direct Current Stimulation for Motor Function and Fatigue in PD
RECRUITING · NA
-
Study to Investigate Vagus Nerve Stimulation to Augment Executive Function in Healthy and Cognitively Impaired Populations
RECRUITING · NA
-
Investigating Subcortical Contributions to Speech Sequencing in Deep Brain Stimulator Recipients
RECRUITING · NA
-
Electrophysiology-based DBS Programming for PD
RECRUITING · NA
-
A Study of NE3107 in Early Parkinson's
RECRUITING · Phase 2
-
Enrichment of Glutathione Using Gamma-glutamylcysteine Supplementation in Parkinson's Disease Patients.
RECRUITING · Phase 1
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01535430 · 75 participants
Assessment of Eloquent Function in Brain Tumor Patients
- NCT01542879 · 75 participants · Phase 1
Development of Radiation Free Whole Body Magnetic Resonance (MR) Imaging Technique for Staging Children With Cancer
- NCT02232191 · 75 participants · Phase 2
Immunologic Response to Pneumococcal Polysaccharide Vaccine in Splenic Injury Patients
- NCT02754544 · 75 participants · NA
Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI