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NCT03033498 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous Infusions of ABBV-951 in Subjects With Parkinson's Disease
A Phase 1 study of Parkinsons Disease (PD), sponsored by AbbVie.
- Completed
- Registry status
- Phase 1
- Development phase
- 29
- Enrollment target
- 7
- Study locations
NCT03033498: Completed Phase 1 study of Parkinsons Disease (PD), sponsored by AbbVie.
NCT03033498 is a Phase 1 study of Parkinsons Disease (PD) that has completed, run by AbbVie. The registered enrollment target is 29 participants, below the 118-participant average among 19 other Parkinsons Disease (PD) trials with a reported enrollment target (75% lower). The trial reports 7 study locations across 7 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT03033498, a Phase 1 study of Parkinsons Disease (PD), has completed, sponsored by AbbVie.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 29 participants
- Enrollment target
- 7
- Study locations
Study Summary
The purpose of the study is to assess the safety, tolerability, and pharmacokinetics of single, ascending doses of ABBV-951 administered as a subcutaneous bolus infusion followed by a continuous subcutaneous infusion in subjects with Parkinson's disease.
Primary Outcome
Maximum observed plasma concentration of levodopa following a single infusion of ABBV-951.
Conditions Studied
Interventions
- DRUG ABBV-951
Study Locations (7)
California
- Glendale Adventist Medical Ctr /ID# 166512 - Glendale
Florida
- Bioclinica Research - Orlando /ID# 169687 - Orlando
Illinois
- Acpru /Id# 154976 - Grayslake
Kentucky
- University of Kentucky Chandler Medical Center /ID# 169086 - Lexington
Maryland
- Parexel Baltimore /ID# 169255 - Baltimore
Michigan
- QUEST Research Institute /ID# 166035 - Farmington Hills
North Carolina
- Carolina Phase I, LLC /ID# 166034 - Raleigh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 29 participants |
| Start Date | 2017-05-17 |
| Est. Completion | 2019-06-08 |
| Phase | Phase 1 |
What the finished NCT03033498 record still lists
NCT03033498 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 29 participants, a relatively small participant target, below the 118-participant average among 19 other Parkinsons Disease (PD) trials with a reported enrollment target (75% lower).
The record links to 1 condition, with Parkinsons Disease (PD) appearing as the primary indexed condition, and to 1 intervention - of which ABBV-951 is the first listed.
NCT03033498 lists 7 locations in 7 states (California, Florida, Illinois).
Frequently Asked Questions
What is clinical trial NCT03033498 about?
NCT03033498 is a clinical study titled "A Study to Evaluate the Safety, Tolerability, and Pharmacokinetics of Subcutaneous Infusions of ABBV-951 in Subjects With Parkinson's Disease". The purpose of the study is to assess the safety, tolerability, and pharmacokinetics of single, ascending doses of ABBV-951 administered as a subcutaneous bolus infusion followed by a continuous subcutaneous infusion in subjects with Parkinson's disease.
What is the current status of trial NCT03033498?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 29 participants. The study started on 2017-05-17. Estimated completion is 2019-06-08.
What conditions does trial NCT03033498 study?
This clinical trial studies the following conditions: Parkinsons Disease (PD).
What interventions are being tested in trial NCT03033498?
The interventions under investigation include: ABBV-951 (DRUG).
Who is sponsoring clinical trial NCT03033498?
This trial is sponsored by AbbVie, which has 526 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT03033498 being conducted?
This trial has 7 study locations across California, Florida, Illinois, Kentucky, Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Parkinsons Disease (PD)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT03033498's enrollment target sits among peer trials
29 16th of 19 higher than 4 of 19 other Parkinsons Disease (PD) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Parkinsons Disease (PD) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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